Structure of PDB 6zqc Chain UQ Binding Site BS01

Receptor Information
>6zqc Chain UQ (length=832) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYKLSVVSGGKPALNNLSSVTGNKNIARLSQDQRNYIIPFNNQIKVYSVE
TRQCVKTLKFANNSLLSGIFLQEEENNESIVKILLGDITVPQQAHLITVF
TNNGHVIVLNYKGKLVESPKHFKISLADEKLANVFHSEGNYRILTTFKDN
SLQSYRLYALTFDDAKKQFEVAHQAEWHNVILSNISSNGKLLAHMCKDVS
TKDHEHKSISVVSLFDDSVNLSFPLGSILSSQTQSLSYNTRYVSSMAIDN
MGQQLAVGFASGVISIVSLADLQIRLLKWHIDSVLSLSFSHDGSYLLSGG
WEKVMSLWQLETNSQQFLPRLNGIIIDCQVLGPQGNYYSLILQMTENNSN
SDYQFLLLNASDLTSKLSINGPLPVFNSTIKHIQQPISAMNTKNSNSITS
LNHSKKKQSRKLIKSRRQDFTTNVEINPINKNLYFPHISAVQIFDFYKNE
QVNYQYLTSGVNNSMGKVRFELNLQDPIITDLKFTKDGQWMITYEIEYPP
NDLLSSKDLTHILKFWTKNDNETNWNLKTKVINPHGISVPITKILPSPRS
VNNSQGCLTADNNGGLKFWSFDSHESNWCLKKISLPNFNHFSNSVSLAWS
QDGSLIFHGFDDKLQILDFDTFKKFESLENTKTVSEFTLDSEIQTVKLIN
DTNLIVATRTTLNAINLLRGQVINSFDLYPFVNGVYKNGHMDRLITCDER
TGNIALVINQQLTDVPTINYKSRIIIFDSDLSTKLGNFTHHEYISWIGWN
YDTDFIFLDIESTLGVVGTNSDIFAEQLHKLNDEDEEDIALEFINGEKKD
KLVNMNSFTSMFDNIQNVQMDTFFDRVMKVLT
Ligand information
>6zqc Chain D2 (length=446) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaug
.<<<....>>>...<<<<<<<<<..>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<...<<<<<..<<<<<<<<<<.<<
<<<<<<....>>>>>>>>.>>>>>>>>>>.>>>>>..>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<..<
<<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>
>.....<<<<<<...<<<<<<<<<<<<<<<<........>>>>>>>.>.>
>>>>>>>....>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqc 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		N166 S167 I197 H220 K223 L252 Y254 N255 Y258 V259 F275 V279 K294 W295 I297 E318 Q332 F333 P335 R336 M406 R426 R433 G482 N535 S554 P556 F607
Binding residue
(residue number reindexed from 1)		N150 S151 I181 H204 K207 L236 Y238 N239 Y242 V243 F259 V263 K278 W279 I281 E302 Q316 F317 P319 R320 M390 R410 R417 G466 N519 S538 P540 F591
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:2000234 positive regulation of rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005777 peroxisome
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0033553 rDNA heterochromatin
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqc, PDBe:6zqc, PDBj:6zqc
PDBsum6zqc
PubMed32943521
UniProtQ02931|UTP17_YEAST NET1-associated nuclear protein 1 (Gene Name=NAN1)

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