Structure of PDB 7ajt Chain UK Binding Site BS01

Receptor Information
>7ajt Chain UK (length=242) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRKQSTLKVL
REKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKT
QDSNYVRTLRQIELKKLEKGAKQLMFKSSGNHTIFVDSREKMNEFTPEKF
FNTTSEMVNRSENRLTKDQLANASSIMPKESLDKKKLKKFKQVKQHLQRE
TQLKQVQQRMDAQRELLKKGSKKKIVDSSGKISFKWKKQRKR
Ligand information
>7ajt Chain D2 (length=446) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaug
.<<<....>>>...<<<<<<<<<..>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<<..<<<<<..<<<<<.<<<<.<<
<<<<<<....>>>>>>>>.>>>>.>>>>>.>>>>>.>>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<...
<<<<<<..<<<....<<<<<....>>>>>...>>>..>>>>.>>..>>>>
>.....<<<<<<.....<<<<<<<<<<<<<<........>>>>>>>.>.>
>>>>>......>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ajt Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		R82 L91 M93 E149 K150 S156 M185 E188 K193 K196 R217 K227 G228 K230 K231 I240 K246
Binding residue
(residue number reindexed from 1)		R81 L90 M92 E148 K149 S155 M177 E180 K185 K188 R209 K219 G220 K222 K223 I232 K238
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006412 translation
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ajt, PDBe:7ajt, PDBj:7ajt
PDBsum7ajt
PubMed33326748
UniProtP34247|UTP11_YEAST U3 small nucleolar RNA-associated protein 11 (Gene Name=UTP11)

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