Structure of PDB 6rxt Chain UH Binding Site BS01

Receptor Information

>6rxt Chain UH (length=359) Species: 209285 (Thermochaetoides thermophila)

SWSEWQNKAMQADELLQNNDIQSWEELMAEVFKPEWEWPSSRSDYARVDR
RWVVYAINKVFGWEGQNTGRLTCRLPESSVLIYLVDAGHLSTSNVKSAFK
DDVREVDKVEELIGEQLPIILAEVDPTMELLVGYLSGTQLGSSELVSSIK
LLLCSLGLDEHRTRGLGIAFSKLAACPAAETVKSLRRLFKPDEVLVLLNV
LRAELIKDGWTTRYLDIQLIADLMSRCIDAVGLSGWMANFFSQFQAEISV
ALEGVMEAVRLKGVIAEAANYAKRARRALADSAKGKAMTVHMSAELPLGL
KTDNKISTERVRSGGEIVARSSRQIGHFISKRRGIYSIHRISEEMLLGAA
GPTVVQEAR

Ligand information

>6rxt Chain C1 (length=1152)

ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guuggggaagcccuagcggcugaaccucucggucgggccuccucuugggg
cgccuaggcggugucuucgggucgcgugcagccucccguccucgccugcc
gacagcgcucuggggaauucaggaggggaaagcagaugugccccgcggcg
agacuggcgcaccgccggacgagcugcuggggcacgcggguacgcuagcc
gcacgauaguuaccugguugauucugcuagucauaugcuugucucaaaua
cccaaucccgacacggggagguagugacaauaaauacugauacagggcuc
uuucgggucuuguaauuggaaugaguacaauuuaaaucccuuaacgagga
acaauuggagggcaagucuggugccagcagccgcgguaauuccagcucca
auagcguauauugcucguaguugaaccugauuaauagggacagucggggg
cgucaguauucaauugucagaggugaaauucuuggauuuauugaagacua
acaacugcgaaagcauucgccaaggauguuuucauuaaucaggaacguaa
acuauuagggaucggacggcguuuauuuuugacccguucggcaccuuacg
auaggaguauggucgcaaggcugaaaaauugacggaagggcaccaccagg
gguggagccugcgcgcgcgcuacacugacagagccagcgaguacucccuu
ggccgagaggcccggguaaacucugucgugcugaggaaucccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauagaggaaguaggucuccguaggugaaccugcgg
ag

<<<<<<.<.<<<<<<....>>>>>>.>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<..<<...<<<<.....>>>>...>>..>>>>>.>>>>>>>>.....<<<
<<<...<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>
....>>>>>>...........................<<<<.<<<<<<<.
.<.<<<<<.....>>>>>.>..>>>>>..>>>>>><<<<.<.....>.>>
>>...........................<<.<<<<<<...<.<<..<.<
<<...<<<<.....>>>.>>>>..>>...>.>....<<<<<<<<<<<<<<
....>>>>>>>>>.>>>>>.....<<..<...........>..>>.....
....<<<<<<.......<<<....>>>..................>>>>>
>..>>>>>>>>.<.<<...<<<.<<.....>>....<<<<<<.<<...<<
<<..<<<.<<<<<<.<...<<<......>>>......>.>>>>>>.>>>.
......<<....>>...>>>>..>>.>>>.>>>...>>>...>>.>....
.......<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>.....
..............................<<<<<<<<<<<<..<<.<<<
<<<..<<<.<<<..>>>.>>>.....<<<<<<<..............<<.
<<<<....>>>>.>>.....>>>>>>>..........>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>............
>>>>>..<<<<.<<......>>.>>>>...<<<<<<<<<....>>>>>>>
>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6rxt Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
• Resolution: 7.0 Å
• Binding residue (original residue number in PDB): K857 K876 I877 T879 R883 S884 S893 R894 G897 H898 I900 R904
• Binding residue (residue number reindexed from 1): K286 K305 I306 T308 R312 S313 S322 R323 G326 H327 I329 R333

Gene Ontology

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:6rxt, PDBe:6rxt, PDBj:6rxt
• PDBsum: 6rxt
• PubMed: 31378463
• UniProt: P0CT47|Y1780_CHATD Uncharacterized protein CTHT_0071780 (Gene Name=CTHT_0071780)