Structure of PDB 6rxz Chain UE Binding Site BS01

Receptor Information
>6rxz Chain UE (length=125) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGTVLNQALRTDDSDLLESCLQTLIIQNTINRMDSSLAGTLLSKLAARMH
RRPGRAFGLMRWIQWTLVAHGGALVTQPDLINRLTELSRVLEERSRGLSS
LLALKGKLDMLDAQLKYRKALKMAG
Ligand information
>6rxz Chain C1 (length=1487) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guugucucggucgggccuccucuuggggcgccuaggcggugucuucgggu
cgcgugcagccucccguccucgccugccgacagcgcucuggggaauucag
gaggggaaagcagaugugccccgcggcgagacuggcgcaccgccggacga
gcugcuggggcacgcggguacgcuagccgcacgauaguuaccugguugau
ucugcuagucauaugcuugucucaaauaagccaugcgucuaaguauaagc
aauuacagcgaaacugcgaauggcucauuaaaucaguuaucguuuauuug
auaguaccuuacuauggauaaccgugguaauucuagagcuaauacaugca
aaaucccgacuucggaagggauguauuuauuagagcccuucggggcggug
auucauaauaacuucucgaaucgcacggccuugcgccggcgaugguucau
ucaaauuucugcccuaucaacuuucgacggcuggguauuggccagccgug
gugacaacggguaaggguuagggcucggagaaggagccugagaaacggcu
acuacauccaaggaagggcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauacugauacagggcucuuucgggucuuguaauu
ggaaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagu
cuggugccagcagccgcgguaauuccagcuccaauagcguauauugcucg
uaguugaaccugauuaauagggacagucgggggcgucaguauucaauugu
cagaggugaaauucuuggauuuauugaagacuaacaacugcgaaagcauu
cgccaaggauguuuucauuaaucaggaacgauuagggaucggacggcguu
uauuuuugacccguucggcaccuuacgauaaaucaaaaggaguauggucg
caaggcugaaaaauugacggaagggcaccaccagggguggagccugcgcg
cgcgcuacacugacagagccagcgaguacucccuuggccgagaggcccgg
guaaacucugucgugcugaggaaucccuaguaagcgcaagucaucagcuu
gcguugauuacgucccugcccuuuguacacaccgcccgucgcuacuaccg
auagaggaaguaggucuccguaggugaaccugcggag
<<<<<<.<<.<<<<<....>>>>>.>>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<.....>>>>>.>>>>>>>>.....<<<<<<...<<<<<<<....<<<<.
.<<.....>>..>>>>....>>>>.>>>....>>>>>>............
...............<<<<<<<<<<<<..<.<<<<<.....>>>>>.>..
>>>>>.>>>>>>><<<<.........>>>>....................
.......<<.<<<<<<...<.<<..<...<<<.<<<<<....<<....<<
.......>>...>>.>>......<<<.......<<<..<<..<<....<<
<.............<<..<..<..<<<.....>>>..>.....>>>....
..<<<<<..........>>>>><...<<<<<<..<<<<....>>>>....
.....>>>>>>.....>...<<<<.<<<<.....>>>>>>>>....>>>.
..>>>>..>>>.<<<....<<.....<<<<<<<<.......>>>>>>>>.
>>......>>>...<<<......>>>.>>>.<<.<<<<........>>>>
.>>.<.<<<..>>>.>.>>>>>>.........<<<....<<<<...>>>>
..>>>..>>...>.>....<<<<<<<<<<<<<<....>>>>>>>>>.>>>
>>.....<<..<...........>..>>.........<<<<<<.......
<<<....>>>..................>>>>>>..>>>>>>>>.<.<<.
..<<<.<<.....>>....<<.<<<.<<...<<<<..<<<.<<<<<<...
..<<<......>>>........>>>>>>.>>>.......<<....>>...
>>>>..>>.>>>..>>...>>>...>>.>.....<<..<<<<<<<<.<<<
.......>>>>>>>>>>>..>>.....<....>.................
...............<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>
>>.>>>.....<<<<<<<..............<<.<<<<....>>>>.>>
.....>>>>>>>..........>>>>>>....<<<<<<<.........>>
>>>>>......>>...>>>>>>>............>>>>>..<<<<.<<.
.....>>.>>>>...<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxz Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		Q174 R203 R207 R210
Binding residue
(residue number reindexed from 1)		Q22 R48 R52 R55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxz, PDBe:6rxz, PDBj:6rxz
PDBsum6rxz
PubMed31378463
UniProtG0RYX2

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