Structure of PDB 6rxv Chain UD Binding Site BS01

Receptor Information
>6rxv Chain UD (length=772) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDIHRCRFVRYPASAINAVAFTHSALPVVSSSKKYLQKNIQVRLAIGRAN
GDIEIWNPLNGGWYQEVIIPGGKDRSVDGLVWVTDPDEEMADGKIIHGKS
RLFSIGYTTTITEWDLEKARAKKHASGQHGEIWCFGVQPLPAAQNRKLVA
GTVDGNLVLYSIEDGDLKFQKTLTRTPSKKTKFVSIAFQSHNIVIVGCSN
STICAYDVRTGTMLRQMTLGTDLTGGSKNIIVWAVKCLPNGDIVSGDSTG
QVCIWDGKTYTQAQRIQSHTQDVLCLSVSADGSKIISGGMDRRTAVYEPM
AGQSGRWSKVFHRRYHQHDVKAMASFEGKGMSVVVSGGSDASPIVLPLRA
LGKEFHRTLPHLPQHPTVLSAPKARYILSWWENEIRIWHLLNSAQQFLPL
NLRKNRKFLAQVLIKGASHITSASISEDGTLLAASTPTDVKVFHLDPLYI
KKVNMTGTGLGATRVQISPDKRWICWAEEGSKVMISRVHATESADGISYT
VSVPHKLHRLRRQIPKHILLGGLGSYDRNVSQIAFSADSRMLSVADLAGY
IDTWVLRGPAGERWARNPKAAMIPKLSAAPVVLSFSPTPRDDGDYDLLVV
TTLKQLLIFNPLRGMLSEWSRRNTYPKLPEPFRDTRDQVKGIVWQGQRAW
FYGVASLFMFDLSQDFSKRKRGAHESGAGSKIEKHSLVPQRIRAASAPDG
TKWEDIEMVDGSELQRLREENRAKWWHTYQFRPIMGIVPIEGIPPLEVAL
IERPLSEDDLPERYFAEGEWER
Ligand information
>6rxv Chain C1 (length=1575) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guuggggaagcccuagcggcugaaccucucggucgggccuccucuugggg
cgccuaggcggugucuucgggucgcgugcagccucccguccucgccugcc
gacagcgcucuggggaauucaggaggggaaagcagaugugccccgcggcg
agacuggcgcaccgccggacgagcugcuggggcacgcggguacgcuagcc
gcacgauaguuaccugguugauucugcuagucauaugcuugucucaaaua
agccaugcgucuaaguauaagcaauuauacagcgaaacugcgaauggcuc
auuaaaucaguuaucguuuauuugauaguaccuuacuacauggauaaccg
ugguaauucuagagcuaauacaugcugaaaaucccgacuucggaagggau
guauuuauuagauuaaaaaccaaugcccuucggggcggugauucauaaua
acuucucgaaucgcacggccuuggccggcgaugguucauucaaauuucug
cccuaucaacuuucgacggcuggguauuggccagccguggugacaacggg
uaaggguuagggcucggagaaggagccugagaaacggcuacuacauccaa
ggaagggcaggcgcgcaaauuacccaaucccgacacggggagguagugac
aauaaauacugauacagggcucuuucgggucuuguaauuggaaugaguac
aauuuaaaucccuuaacgaggaacaauuggagggcaagucuggugccagc
agccgcgguaauuccagcuccaauagcguauauugcucguaguugaaccu
gggccuagcccgccgguccgccucaccgcgugcacuggcugggcugggcc
ugauuaauagggacagucgggggcgucaguauucaauugucagaggugaa
auucuuggauuuauugaagacuaacaacugcgaaagcauucgccaaggau
guuuucauuaaucaggaacguaaacuauuagggaucggacggcguuuauu
uuugacccguucggcaccuuacgauaggaguauggucgcaaggcugaaaa
auugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
ggucuccguaggugaaccugcggag
<<<<<<.<<<<<<<<....>>>>>>>>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<..<<...<<<<.....>>>>...>>..>>>>>.>>>>>>>>.....<<<
<<<...<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>
....>>>>>>...........................<<<<<<<<<<<<.
.<.<<<<<.....>>>>>.>..>>>>>.>>>>>>><<<<.........>>
>>...........................<<.<<<<<<...<.<<.....
.<<<.<<<<<....<<....<<.........>>...>>.>>......<<<
.......<<<..<<..<<....<<<...............<<.....<..
<<.......>>..>......>>........<<<<<..........>>>>>
<...<<<<<<..............<<<<....>>>>.........>>>>>
>.....>...<<<<.<<<<....>>>>>>>>....>>>...>>>>..>>>
.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>
...<<<<....>>>>.>>>.<<.<<<<........>>>>.>>.<.<<<..
>>>.>.>>>>>>.........<<<...<<<<.....>>>.>>>>...>..
.>.>....<<<<<<<<<<<<<<....>>>>>>>>>.>>>>>.....<<..
<...........>..>>.........<<<<<<.......<<<....>>>.
.................>>>>>>..>>>>>>>>.<.<<...<<<.<<...
<<<<<<<<<<<<<<<<<.<<<......>>>...>>>>>>.>>>>>>>>>>
>..>>....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<.....
.>>>......>.>>>>>>.>>>.......<<....>>...>>>>..>>.>
>>.>>>...>>>...>>.>...........<<..<<<<<<<<.<<<....
...>>>>>>>>>>>..>>................................
...<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>..<<<<.<<......>>.>>>>
...<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxv Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		R5 K186 S233 K234 N235 H318 R319 R320 F361 H362 R363 T364 D684 T685 R686 R734 S745 H750 Y830 Q831 R833 R884
Binding residue
(residue number reindexed from 1)		R5 K180 S227 K228 N229 H312 R313 R314 F355 H356 R357 T358 D634 T635 R636 R669 S680 H685 Y729 Q730 R732 R772
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034455 t-UTP complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxv, PDBe:6rxv, PDBj:6rxv
PDBsum6rxv
PubMed31378463
UniProtG0SCT7

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