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Receptor Information

>6rxt Chain UD (length=772) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MDIHRCRFVRYPASAINAVAFTHSALPVVSSSKKYLQKNIQVRLAIGRAN
GDIEIWNPLNGGWYQEVIIPGGKDRSVDGLVWVTDPDEEMADGKIIHGKS
RLFSIGYTTTITEWDLEKARAKKHASGQHGEIWCFGVQPLPAAQNRKLVA
GTVDGNLVLYSIEDGDLKFQKTLTRTPSKKTKFVSIAFQSHNIVIVGCSN
STICAYDVRTGTMLRQMTLGTDLTGGSKNIIVWAVKCLPNGDIVSGDSTG
QVCIWDGKTYTQAQRIQSHTQDVLCLSVSADGSKIISGGMDRRTAVYEPM
AGQSGRWSKVFHRRYHQHDVKAMASFEGKGMSVVVSGGSDASPIVLPLRA
LGKEFHRTLPHLPQHPTVLSAPKARYILSWWENEIRIWHLLNSAQQFLPL
NLRKNRKFLAQVLIKGASHITSASISEDGTLLAASTPTDVKVFHLDPLYI
KKVNMTGTGLGATRVQISPDKRWICWAEEGSKVMISRVHATESADGISYT
VSVPHKLHRLRRQIPKHILLGGLGSYDRNVSQIAFSADSRMLSVADLAGY
IDTWVLRGPAGERWARNPKAAMIPKLSAAPVVLSFSPTPRDDGDYDLLVV
TTLKQLLIFNPLRGMLSEWSRRNTYPKLPEPFRDTRDQVKGIVWQGQRAW
FYGVASLFMFDLSQDFSKRKRGAHESGAGSKIEKHSLVPQRIRAASAPDG
TKWEDIEMVDGSELQRLREENRAKWWHTYQFRPIMGIVPIEGIPPLEVAL
IERPLSEDDLPERYFAEGEWER

>6rxt Chain C1 (length=1152) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guuggggaagcccuagcggcugaaccucucggucgggccuccucuugggg
cgccuaggcggugucuucgggucgcgugcagccucccguccucgccugcc
gacagcgcucuggggaauucaggaggggaaagcagaugugccccgcggcg
agacuggcgcaccgccggacgagcugcuggggcacgcggguacgcuagcc
gcacgauaguuaccugguugauucugcuagucauaugcuugucucaaaua
cccaaucccgacacggggagguagugacaauaaauacugauacagggcuc
uuucgggucuuguaauuggaaugaguacaauuuaaaucccuuaacgagga
acaauuggagggcaagucuggugccagcagccgcgguaauuccagcucca
auagcguauauugcucguaguugaaccugauuaauagggacagucggggg
cgucaguauucaauugucagaggugaaauucuuggauuuauugaagacua
acaacugcgaaagcauucgccaaggauguuuucauuaaucaggaacguaa
acuauuagggaucggacggcguuuauuuuugacccguucggcaccuuacg
auaggaguauggucgcaaggcugaaaaauugacggaagggcaccaccagg
gguggagccugcgcgcgcgcuacacugacagagccagcgaguacucccuu
ggccgagaggcccggguaaacucugucgugcugaggaaucccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauagaggaaguaggucuccguaggugaaccugcgg
ag

<<<<<<.<.<<<<<<....>>>>>>.>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<..<<...<<<<.....>>>>...>>..>>>>>.>>>>>>>>.....<<<
<<<...<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>
....>>>>>>...........................<<<<.<<<<<<<.
.<.<<<<<.....>>>>>.>..>>>>>..>>>>>><<<<.<.....>.>>
>>...........................<<.<<<<<<...<.<<..<.<
<<...<<<<.....>>>.>>>>..>>...>.>....<<<<<<<<<<<<<<
....>>>>>>>>>.>>>>>.....<<..<...........>..>>.....
....<<<<<<.......<<<....>>>..................>>>>>
>..>>>>>>>>.<.<<...<<<.<<.....>>....<<<<<<.<<...<<
<<..<<<.<<<<<<.<...<<<......>>>......>.>>>>>>.>>>.
......<<....>>...>>>>..>>.>>>.>>>...>>>...>>.>....
.......<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>.....
..............................<<<<<<<<<<<<..<<.<<<
<<<..<<<.<<<..>>>.>>>.....<<<<<<<..............<<.
<<<<....>>>>.>>.....>>>>>>>..........>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>............
>>>>>..<<<<.<<......>>.>>>>...<<<<<<<<<....>>>>>>>
>>

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6rxt Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution	7.0 Å
Binding residue (original residue number in PDB)	K186 K188 S233 K234 N235 H318 R319 R320 F361 H362 R363 T364 D684 T685 R686 R734 S745 H750 Y830 Q831 R833 R884
Binding residue (residue number reindexed from 1)	K180 K182 S227 K228 N229 H312 R313 R314 F355 H356 R357 T358 D634 T635 R636 R669 S680 H685 Y729 Q730 R732 R772

Enzyme Commision number

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

	Cellular Component
GO:0030686	90S preribosome
GO:0032040	small-subunit processome
GO:0034455	t-UTP complex

PDB	RCSB:6rxt, PDBe:6rxt, PDBj:6rxt
PDBsum	6rxt
PubMed	31378463
UniProt	G0SCT7

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Structure of PDB 6rxt Chain UD Binding Site BS01