Structure of PDB 6zqc Chain UB Binding Site BS01

Receptor Information
>6zqc Chain UB (length=507) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQRKKTKAEVMKEVIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSEL
MMTDLDKEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELEQQRL
DRMNGRTHDALLDQVKKLDLDDHPKIVKNIIKAYQPKLEKLGKFTAVLLR
HIIFLSNQNYLKNVQSFKRTQNALISILKSLSEKYNRELSEECRDYINEM
QARYKKNHFDALSNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQ
IKFNSLKRIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVEPLD
FENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMDTEAHPVDQCVSVLL
NVMESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYSDFEKPRNILNK
VEKLTKFTEHIPLALQNHKPVSIPTHAPKYEDRTRSEINKMKAQLKKERK
FTMKEIRKDAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNKY
ERERKLR
Ligand information
>6zqc Chain D3 (length=1327) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccagucauaugcuugucucaaagauu
aagccaugcaugucuaaguauaagcaauuuauacagugaaacugcgaaug
gcucauuaaaucaguuaucguuuauuugauagcaugguauaacuguggua
auucuagagcuaauacaugcuaucucgacccuuuggaagagauuauuuau
uagauucuucggacucuugaugauucauaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggcgcgcaaauuacccaauccuaauucagggagguagugacaauaa
auaacgauacagggcccauucgggucuuguaauuggaaugaguacaaugu
aaauaccuuaacgaggaacaauuggagggcaagucuggugccagcagccg
cgguaauuccagcuccaauagcguauauugcucguaguugaacuuugggc
ccgguuggccggucggauuuccaacggggccuuuuuacuuugaaaaaauu
agaguguucaaagcaggcguauugcucgauauauuagcauggaauaauag
gacguuugguucuauuuuguugguuucuaggaccaucguaauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaacuaugccgacuagggaucgggugguguuuuuuuaaugac
ccacucggcaccuuacgaggaguauggucgcaaggcugaaacuuaaagga
auugacggaagggcaccaccaggaguggagccugcggaaacucaccaggu
ccagacacaauauuugugggugguggugcaugugaugcccuuguucuggc
gcgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuu
gguaaaaacuccgucggggaacgaggaauuccuaguaagcgcaagucauc
agcuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuag
uaccgauugaauggcuuagugaggccucaggaucugcuuagagaaggggg
caacuccaucucagagcggaaauuuggacaaacuuggucauuuagaggaa
cuaaguuuccguaggugaaccugcgga
...........................<<.<<<<<<...<.<........
..<<<.<<<..<<....<<....<<..........>>...>>.>>.....
.<<..<.....<<<..<<..<<....<<<.......<<....<<.<<<..
...>>>.>>.....>>.....<<<<<..<<....>>..>>>>>...<<<<
<<...<<....>>....<<......>>>>>>>>.........<<<<.<<<
<.....>>>>>>>>....>>>...>>>>..>>>.<<<....<<......<
<<<<<<.......>>>>>>>..>>......>>>...<<<<<<<<....>>
>>...>>>>>>>.<<.<<<<........>>>>.>>.<.<<<..>>>.>..
.>>>>>>.........<<<....<<<.....>>>..>>>.......>.>.
....<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<....
.......>..>>.........<<<<<<.......<<<....>>>......
............>>>>>>..>>>>>>>>.<.<<...<<<.<<....<<<<
<<.<<<<<............>>>>>.>>>>>>..<<<<<.<<......<.
...<<.......>>..<<.....>>.....>......>>.>>..>>>...
.<<<...<<<<<<...............>>>>>>..>>>..>>....<<<
<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.
>>>>>>..>>.......<<....>>...>>>>..>.>>>>.>>>...>>>
...>>.>..........<<...<<<..<<<<<<<<.<<<........>>>
>>>>>>>>..>>>..>>..................<<.........>>..
...<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<<........<<<<<.
<....<<<<<...>>>>>......<<<.<<..>>..>>>...>.>>>>>>
>>>.>>>.....<<<<<<<............<<<..<<<<....>>>>..
>>>.....>>>>>>>............>>>>>>....<<<<<<<<.....
..>>>>>>>>......>>...>>>>>>>............>>>>>..<<<
<.<<....<<<<<<<<.<<<..<.<<..<...<<<<<<<...<<.<.<..
....>.>.>>...>>>>>>>..>..>>.>..>>>.>>>>>>>>...>>.>
>>>....<<<<<<<<....>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6zqc 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		V210 A216 K745 K749 H778 A779 A782 H783 N786
Binding residue
(residue number reindexed from 1)		V10 A16 K446 K450 H479 A480 A483 H484 N487
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0030692 Noc4p-Nop14p complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqc, PDBe:6zqc, PDBj:6zqc
PDBsum6zqc
PubMed32943521
UniProtQ99207|NOP14_YEAST Nucleolar complex protein 14 (Gene Name=NOP14)

[Back to BioLiP]