Structure of PDB 7oyb Chain U2 Binding Site BS01

Receptor Information
>7oyb Chain U2 (length=97) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RIRITLTSRNVKSLEKVCADLIRGAKEKSLKVKGPVRMPTKTLRITTRKT
PCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVT
Ligand information
>7oyb Chain 22 (length=1502) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguaauauaugcuugucucaaagauuaagcca
ugcaagucuaagugcacacgagugaaacugcgaauggcucauuaaaucag
uuaugguuccuuugaucacuuggauaacuguggcaauuccagagcuaaua
caugcgccgcgugcauuuaucaguggugacucuagauaacgccgaucgcg
cgcgcggcgacgguucauucgaaugucugcccuaucaacuuucgauggua
gguccgucgccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccauuuccgacacggagagguagugacgaaaaauaa
caauuuggaaugagugcaucccaaacccaugggcgaggacccauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaugc
uaacguugcugcaguuaaaaagcucguaguuggaucucuuuacuuugaaa
aaauuagaguguucaaggcagggccccccauugaauaccccagcuaggaa
uaauggaauaggaccccggggccaugaucgagagggacggccgggggcau
ucguauugcgccgcuagaggugaaauucuuggaccggcgcaagacggacc
ggagcgaaagcguuugccaagaacguuuucauuaaucaagaacgaaaguc
ggagguucgaagacgaucagauaccgucguaguuccgaccguaaacgaug
ccgacccgcgauccggcggcguuugacccgccgggcagcguugcgggaaa
ccacgagucucugggcuccggggggaguaugguugcaaagcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcuuaauuu
gacucaacacggggaaccucacccggcccggacaauugacagauucucga
uucugugggugguggugcauggccguucguaguugguggagcgauuuguc
ugguugauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcg
gccggucggcguaacuucuuagagggacaaguggcguucagccacgcgag
acugagcaauaacaggucugugaugcccuuagauguccggggcugcacgc
gcgccacaaugggcggaucaacguguccugcgccgacaggcgcggguaac
ccguugaaccccgcccgugauggggaccgauugaaacuauuucccgagaa
cgaggaauucccaguaagcgcaggucaucagcuugcguugauuaaguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugagcggcucagug
agguccucggaucggcgccgagaagacgaucgaacucggucguuuagagg
aaguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucau
ua
...<<<<<.[.((((>>>>><<.<<<<<<<...<.<<..<......<<<.
<<<..<<....<<.............>>.>>......<<........<<<
.<<<..<<....<..<....<<.....<<.<<<.....>>>.>>......
>>..............<<<<<...<......>..>>>>>......<<<..
<....>.>>>..>...>...>>>>>.>>>.<<<....<<<.....<<<<<
<<.......>>>>>>>.>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>
>>>.........<<<....<<<.....>>>..>>>..>...>>.>.....
<<...>>......<<.<<<.........>>>.>>.........<.<<<((
......<<<......<<..))>>........>>>.>>>.>..>>>>>>>.
>>.........<.<((.....<.<<...<<<.<<.....<<<<<<.<...
....<<...<.......>...<<...>>.......>>......>.>>>..
>>>..........<<<..>>>......>>....<<<<<<..<...<<<<.
.<<..<<<<<<<<...<<<......>>>......>>>>>>>.>.>>....
...<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.........>>>>...>>>>>>>>..........<
<<.<<.<<<..<<<<<<<<.<<<.>>>>>>>>>>>..>>>....<<..))
>>....>>.....>>>.>.>.<<<......<<<......>>>....>>>.
.)))).]<<<<<.<<<<<<<..<<..<<<<<....<<............<
<........>>..........<<.<<...........<<.....>>....
........<.<..<<<..<<.<<<<<<....<<<.<<<<<....>>>...
<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<..<<<
<<..>>>.>>..>>>>..>>>>..>.....<<<<<.....>>>>>.....
...>>>....>>>.>>>.....>>>>>.>>......>>.>>.........
>.>.......<<<<<<........<.<<<<<<<<....>>>>>>>>....
>.........>>>>>>............<<..........>>........
......>>>>>.....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<.<<...<<<<..>>>>...>>.>>>>..>>>.>>>>>>>>...>>
.>>>>...>.>>.........<<<<<<<<<<..>>>>>>>>>>.......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oyb A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R21 V29 G52 P53 V54 R55 M56 P57 T58 K59 R62 T64 R66 K67 T68 P69 C70 G71 E72 G73 S74 K75 T76 W77 R79 R83 H85 K86 L88
Binding residue
(residue number reindexed from 1)		R3 V11 G34 P35 V36 R37 M38 P39 T40 K41 R44 T46 R48 K49 T50 P51 C52 G53 E54 G55 S56 K57 T58 W59 R61 R65 H67 K68 L70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oyb, PDBe:7oyb, PDBj:7oyb
PDBsum7oyb
PubMed36653451
UniProtQ6P6E7

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