Structure of PDB 8uua Chain U Binding Site BS01

Receptor Information
>8uua Chain U (length=110) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSAKAVAKTVRIAPRKARIVIDLIRGKQVGEAIAILKYTPRSASPIIEKV
LKSAIANAEHNYDLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRT
SHITVVVSEV
Ligand information
>8uua Chain A (length=2894) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuagcgaauucagauaaacuccgaaugcc
auguacuuauacucgggagucagacugcgagugauaagauccguagucga
aagggaaacagcccagaccaccaguuaagguccccaaauauauguuaagu
ggaaaaggaugugggguugcuuagacaaccaggauguuggcuuagaagca
gccaccauugaaagagugcguaauagcucacuggucgagugaccccgcgc
cgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaaccuag
guucgugguaggagagcguucuaagggcggugaagucagaccggaaggac
ugguggagcgcuuagaagugagaaugccgguaugaguagcgaaagaaggg
ugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcucgucc
gcucaggguuagucgggaccuaagccgaggccgauaggcguaggcgaugg
acaacagguagagauuccuguaccagugcuaauuguuuaaccgauggggu
gacacagaaggauagggaaucgcacgaauggaaaugugcguccaagcagu
gagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugugaug
gggaagcggaaguuccugauuucacgcugucaagaaaagccucuaggaag
aguaguacugcccguaccgcaaaccgacacagguagaugaggagagaauc
cuaaggugagcgagagaacucucguuaaggaacucggcaaaaugaccccg
uaacuucgggagaaggggugcucuauuagggugcaagcccgagagagccg
cagugaauaggcccaggcgacuguuuagcaaaaacacaggucucugcaaa
accguaaggugacguauaggggcugacgccugcccggugcuggaagguua
agaggagugcuuagcuucggcgaagguacgaauugaagccccaguaaacg
gcggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaa
guuccgacccgcacgaaaggcgcaacgaucugggcacugucucaacgaga
gacucggugaaauuauaguaccugugaagaugcagguuacccgcgacagg
acggaaagaccccguggagcuuuacugcaaccugauauggaauguuugua
ccgcuuguacaggauagguaggagccgaagagacgugugcgcuagcauac
gaggaggcaauggugggauacuacccuggcuguaugaccauucuaacccg
ccacgcuaagcgcguggggagacagugucaggugggcaguuugacugggg
cggucgccuccuaaagaguaacggaggcgcccaaagguucccucagaaug
gauggaaaucauucgcagaguguaaaggcacaagggagcuugacugcgag
acugacaagucgagcagggacgaaagucgggcuuagugauccggugguuc
cgcauggaagggccaucgcucaacggauaaaagcuaccccggggauaaca
ggcuuaucucccccaagaguccacaucgacggggagguuuggcaccucga
ugucggcucgucgcauccuggggcuguagucggucccaaggguugggcug
uucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacag
uucggucccuauccgucgcgggcgcaggaaauuugagaggagcuguccuu
aguacgagaggaccgggauggacacaccgcugguguaccaguuguuccgc
caggagcaucgcuggguagcuauguguggcagggauaaacgcugaaagca
ucuaagcgugaagccccccucaagaugagauuucccauuucuucggaaag
uaagaucccugaaagaugaucagguagauagguuuggaguggaaguguag
cgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<........>>>>>>>>..>>.>.....>>
>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<<<<<<.......<<<<<.<<...<<<<.......>
>>>...>>.........<<......>>...>>>>>...>>>>>>>>>>.>
>...........))).....>>>>>>.>>>...>>>>>>><<<<<<<..>
>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>
>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<
.......>>>>>><<<<....<<<<<.<<<..<<<<<<...<<.....>>
.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>
...<<<<<........>>>>>))<<<<<<<<.<<......<<...<<<<<
...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<<<<<
..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>...>
>...........>>>>>...>>>...>>>>........>>>>>..>>..>
>.>>>>>>>>>>>>.>>>.....<<......>>>>>>>.<<<<.....>>
>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.
....<..>......>>>>><<<<<....<<<<....>>>>...>>>>>..
..........<<<<<<<<<..<<<.........>>>..<<<<<<<.....
<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..<<<<.
.<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>>>..>>>
>><<<<<<.......>>>>>>........<...........<<<<<<...
..>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>>>>>>
>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.((
(.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.<<<<<
<.<<<.<.........<<<<<..<<<.......<<<<<<<....>>>>>>
>....>>>............>>>>>>.>>>.>>>>>>.>>>>>....<<.
<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<....
.>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<
<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<
<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.(
(..>>>>..))>>>>>>>.............>>>>..]]>>>>.......
<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.....
..<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<..
...>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>
>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.
..............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.)
))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<.......
....>>>>>...>>>>.>>>>.......>>>>>>>..<<<<....>>>>.
...<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<.
...>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uua Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
V11 R16 R20 K21 R23 P45 R46 S47 K54 S58 A61 N62 H65 N66 D82 E83 R89 R91 P92 R93 A94 Q95 G96 R97 A98 A100 N102 K103 H107
Binding residue
(residue number reindexed from 1)
V6 R11 R15 K16 R18 P40 R41 S42 K49 S53 A56 N57 H60 N61 D77 E78 R84 R86 P87 R88 A89 Q90 G91 R92 A93 A95 N97 K98 H102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8uua, PDBe:8uua, PDBj:8uua
PDBsum8uua
PubMed38407413
UniProtA0A0U5ANW2

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