Structure of PDB 8uqm Chain U Binding Site BS01

Receptor Information
>8uqm Chain U (length=82) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGT
RLDLDRIAHWVGQGATISDRVAALIKEVNKAA
Ligand information
>8uqm Chain D (length=1524) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacg
aguggcggacgggugaguaaugucugggaaacugccugauggagggggau
aacuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagag
ggggaccuucgggccucuugccaucggaugugcccagaugggauuagcua
guaggugggguaacggcucaccuaggcgacgaucccuagcuggucugaga
ggaugaccagccacacuggaacugagacacgguccagacuccuacgggag
gcagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugc
cgcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagg
aagggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaag
caccggcuaacuccggccagcagcccgguaauacggagggugcaagcguu
aaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucaga
ugugaaauccccgggcucaaccugggaacugcaucugauacuggcaagcu
ugagucucguagagggggguagaauuccagguguagcggugaaaugcgua
gagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacug
acgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggua
guccacgccguaaacgaugucgacuuggagguugugcccuugaggcgugg
cuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaag
guuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaugu
gguuuaauucgauaacgcgaagaaccuuaccuggucuugacauccacgga
aguuuucagagaugagaaugugccuucgggaaccgugagacaggugcugc
auggcugucgucagcucguguugugaaauguuggguuaagucccgcaacg
agcgcaacccuuauccuuuguugccagcgguccggccgggaacucaaagg
agacugccagugauaaacuggaggaagguggggaugacgucaagucauca
ugcccuuacgaccagggcuacacacgugcuacaauggcgcauacaaagag
aagcgaccucgcgagagcaagcggaccucauaaagugcgucguaguccgg
auuggagucugcaacucgacuccaugaagucggaaucgcuaguaaucgug
gaucagaaugccacggugaauacguucccgggccuuguacacaccgccgu
acaccaugggaguggguugcaaaagaaguagguagcuuaaccuucgggag
ggcgcuuaccacuuugugauucaugacuggggugaagucgaacaagguaa
ccguaggggccugcgguuggauca
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<..<<<<<<<<<......>>>>>>.>>>>>.
.>>>>>......<<.......<<<<<<<..<<...<<<<<<<.<.<<...
..<<<<<......>>>>>......>>.>.....<<<....>>>....<<<
<<<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<.
.<<<<<<<.........>>>>>>>>>>......>>>..<<<<<<<<....
>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>
...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>
>>>..<<<<......<<<<....>>>>.....>>>>..<<.<<<<<....
..<.<<<<<<<<.......>>>>>>>>.>........>>>>>....>>.<
<<<<(((...<<<<<.......)))........>>>>>>>>>>..>>>>>
>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<
<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>.
..<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>>...
...>>>>>>>>...........<<....>>.>>>>>>>..>>>>.>>>>.
..>>>...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...
>>>>>>>>..........<<<<<<.<<<<<<<<<<<<<.....>>>>>>>
>>>>>>..<<..))>>.....>>>>>>.>>>.<<<......<<<<....>
>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<
<<<......<<......>>..........<<<<<<<......<<<<<<<.
.<<<<<<<....>>>>>>>...<......>..>>>>>.>>.<<<.<....
<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>
>>>.....<<<<.<<<<<<<...<<..<<<.....>>>>>....>>>>>>
>.....<<<<<.....>>>>>........>>>>.........>>>...>>
>.>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<
..<<...<<<....>>>...>>....>>>.....>>>>>>>......<..
..<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<
<.........>>>>>>>......>>...>>>>>>>>>>.>>......<<.
.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<<<<..<<<..>>>.>
>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>....>>........<<
<<<<<<<..>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB8uqm Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Resolution5.3 Å
Binding residue
(original residue number in PDB)		M1 R5 L6 R8 H9 G10 A11 K12 K13 R14 F16 Y17 D23 R25 R28 G30 R31 R35 F38 I42 E47 R51 Q63 G64 S68 R70
Binding residue
(residue number reindexed from 1)		M1 R5 L6 R8 H9 G10 A11 K12 K13 R14 F16 Y17 D23 R25 R28 G30 R31 R35 F38 I42 E47 R51 Q63 G64 S68 R70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uqm, PDBe:8uqm, PDBj:8uqm
PDBsum8uqm
PubMed39117885
UniProtC3SYP2

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