Structure of PDB 8om2 Chain U Binding Site BS01

Receptor Information
>8om2 Chain U (length=237) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIQTNAVNVLQRTSAYLKSGLLKETPAWYNVVASIPPSTKFTREPRFKN
PSNGHIIGKLVDVTEQPHANNKGLYKTRPNSSDKRVGVKRLYRPPKLTYV
EDRLRSLFYKQHPWELSRPKILVENEIGDENYDWSHMLQIGRPLDGESVI
QRTMYLIKTKQYGDMVEAYDHARYEFYALRMQEETEQQVALEEAEMFGSL
FGVSAIEHGIQKEQEVLDVWEKKVVEETELMAARTSN
Ligand information
>8om2 Chain r (length=1486) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacac
augcgaaucauacguuuauuauugauaagauaauaaauaugugguguaaa
cgugaguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacu
uaauauauaaaaaggauauauaauauauuuaucuauagucaagccaauaa
ugguuuagguaguagguuuauuaagaguuaaaccuagccaacgauccaua
aucgauaaugaaaguuagaacgaucacguugacucugaaauauagucaau
aucuauaagauacagcagugaggaauauuggacaaugaucgaaagauuga
uccaguuacuuauuaggaugauauauaaauauauauauauaaauugauua
aaaauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauu
uuuauauggauauauuuuaauaguccugacuaauauuugugccagcaguc
gcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauccg
uagaaugaauuauauauuauaauuuagaguuaauaaaauuaauuaaagaa
uuauaauaguaaagaugaaauaaauaauuauaagacuaauauaugugaaa
auauuaauuaaauauuaacugacauugagggauuaaaacuagaguagcga
aacggauucgauacccguguaguucuaguaguaaacuaugaauacaauua
uuuauauauauauauauaaauaauaaaugaaaaugaaaguauuccaccug
aagaguacguuagcaauaaugaaacucaaaacaauagacgguuacagacu
uaagcaguggagcauguuauuuaauucgauaauccacgacuaaccuuacc
auauuuugaauauuauaauaauuaaauuauuauauuacaggcguuacauu
guugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaacgaac
aaaacuccauauauauaauuuuaauuauauauaauuuuauauuauuuauu
aauauaaagaaaggaauuaagacaaucauaaugauccuuauaauaugggu
aauagacgugcuauaauaaaaugauaauaaaauuauauaaaauauauuua
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gaauugcuaguaauacguaaauuaguauguuacggugaauauucuaacug
uuucgcacuaaucacucaucacgcguugaaacauauuauuaucuuauuau
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aaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaacc
ugcggugggcuuauaaauaucuuaaauauucuuaca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<<<<<<<<<<<.....>>>>>>>>>>..>>>>>.....
<<<........<<<<<.<<.........<<<<<<<<.<<<<.......>>
>>...........<<<<<<<<.>>>>>>>>.>>>>>>>>....>>>>>>>
<<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>..
<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>><
<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>..
>>>..>>.>>>>>>.<<<<..<<<<<<........>>>>>>..<<.....
.>>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..
..>>>>>>><<..>>>>>....<<<<<(((.....<<<<.....<<.)))
>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<<.
..<.<<.<<<<<<<...>>>>>>>...<<<<<<<<...<<<<<<<<<<..
<<<<<<<...................>>>>>>>..>>.......<<....
>>.>>>>>>>>.>>>>>>>>...>>>...>>>>....<<<<<<...<<..
.<<<<.........>>>>...>>>>>>>>..........<<<<<<.<<<<
<<<<<<<<<..>>>>>>>>>>>>>..<<..))>>....>>>>>>.>>>.<
<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<<...
.<.<<<<<..<<<<<<<<<<............................<<
<<<<<.....<<.<<<<<<<<<<.>>>>>>>>>>.>>.<<<.<<..<<<<
<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>>>>>>
.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.....>
>>>>>>>>....>>>...>>>>>>>...>>>>>>>>>>...>>>>>>>..
.>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<<<....
..>>>>>>..>>....>>>......>>>>>>......<<<<<........
>>>>>..........<....<<<<<<<........>>>>>>>....>...
..>>>>>.....<<.<<<<<.........>>>>>>>.....>.....>>>
>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<<
..<<<.<<<<<...<<<<<<<..>>>>>>>...>>>>>>>>..>>>..>>
>>>>>>>>>>..>>>>>>>>..>.>>>..>.....<<<<<<<<<....>>
>>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8om2 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Resolution2.57 Å
Binding residue
(original residue number in PDB)
M1 K2 R44 T77 R78 S81 R90 K96 R103 L107 H208
Binding residue
(residue number reindexed from 1)
M1 K2 R44 T77 R78 S81 R90 K96 R103 L107 H208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8om2, PDBe:8om2, PDBj:8om2
PDBsum8om2
PubMed38199006
UniProtP40496|RT25_YEAST Small ribosomal subunit protein mS23 (Gene Name=RSM25)

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