Structure of PDB 8i7j Chain U Binding Site BS01

Receptor Information
>8i7j Chain U (length=106) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QEVVIHKIRINLTSTKVKQLENVSANIIKNAETFKLVKKGPVRLPTKVLK
ISTRKTPNGEGSKTWDTYEMRIHKRYIDLEAPAHIVKRITQITIEPGVDV
EVIIAA
Ligand information
>8i7j Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccggucgguuuuucaaccggaucuuuccuucuggcuaaccuguacuccu
ugugggugcaggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcgaaagcucgaauauauuagcauggaauaauggaauaggacg
uuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggga
cggucgggggcaucaguauucaauugucagaggugaaauucuuggauuua
uugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaauc
aagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuua
accauaaacuaugccgacuagggaucgggugguguuuuucuuaugaccca
cucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaugg
ucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagug
gagccugcggcuuaauuugacucaacacggggaaacucaccagguccaga
cacaauaaggauugacagauugagagcucuuucuugauuuuguggguggu
ggugcauggccguucuuaguugguggagugauuugucugcuuaauugcga
uaacgaacgagaccuuaaccuacuaaauaggguugcuggcacuugccggu
ugacucuucuuagagggacuaucgguuucaagccgauggaaguuugaggc
aauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuac
acugacggagccagcgaguacaaccuuggccgagaggucuggguaaucuu
gugaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagug
aggccucaggauuugcuuagagaagggggcaacuccaucucagagcgaag
aaucuggucaaacuuggucauuuagaggaacuaaaagucguaacaagguu
uccguaggugaaccugcggaaggaucauua
...<<<<<...((((>>>>><<<..<<<<<<...<.<..........<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<................<<.....<<.
<<.......>>.>>......>>........<<<................>
>><...<<<<<<.............................<......>.
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<.....<<<<<<<.......>>>>>>>.>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>................>>>>>>.........<<<....<<<.
....>>>..>>>.......>.>.....<<<..<<<<............>>
>>...>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>.
>>>.........<<<((.....<.<<...<<<.<<....<....<<<<<<
..............>>>>>>....>....<....................
.....................>...<<<<<.<<.......<<...<....
...>..<<<....>>>....>>......>>.>>..>>>.........<<<
......<.................>.......>>>.....>>....<<<<
<<.<<...<<<<..<<<.<<<<<<.....<<.......>>.........>
>>>>>.>>>.......<<....>>...>>>>...>>>>>.>>>...>>>.
..>>.>....<<<<<<..<.....<<<<.........>>>>....>>>>>
>>..........<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>
>>>>>..>>>...<<..))>>...>>.....>>>.>>>.<<<......<<
<......>>>....>>>..))))..<<<<<.<<<<<<<..<<..<<<<<.
.<<<.<<<<<<......<<........>>..........<<<<<......
<<<<<........<<.<<<........>>>.>>......>>>>>...<<.
<<<......<<<<<....<<<.<.<<......>>...<<<......>>>.
...>.>>>....<<<<<.<<..<<<<..<<<<<<<<<<<<....>>>>>>
.>>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>.
...>>>.>>........>>>>>.......>>>>>...>>.>>>>.>>>..
...<<<<<<<......<<.....<<<.<<<<....>>>>.>>>....>>.
......>>>>>>>......<.....<<<<<..........>>>>>.....
>.....>>>>>......<<<<<<<.......>>>>>>>.......>>...
>>>>>>>>>>.>>....<..<<......<<.<<....<<<<<<<<.<<<.
.<<<<..<.....<<<...<....................>...>>>...
..>..>>>>..>>>.>>>>>>>>...>>.>>.......>>...>.....<
<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i7j Yeast eukaryotic initiation factor 4B remodels the mRNA entry site on the small ribosomal subunit
Resolution4.6 Å
Binding residue
(original residue number in PDB)		K21 R23 V31 E35 K53 G54 V56 R57 L58 P59 T60 K61 V62 K64 S66 K69 P71 N72 G73 E74 G75 S76 K77 W79 T81 K88 R89 Y90
Binding residue
(residue number reindexed from 1)		K7 R9 V17 E21 K39 G40 V42 R43 L44 P45 T46 K47 V48 K50 S52 K55 P57 N58 G59 E60 G61 S62 K63 W65 T67 K74 R75 Y76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i7j, PDBe:8i7j, PDBj:8i7j
PDBsum8i7j
PubMed
UniProtQ6CIM1

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