Structure of PDB 8auv Chain U Binding Site BS01

Receptor Information
>8auv Chain U (length=142) Species: 4097 (Nicotiana tabacum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLVANEEFQHILRVQNTNVDGKQKIMFAMTSIKGIGRRFANIACKKADID
MNKRAGELSAAELDSLMVVVANPRQFKIPDWFLNRQKDYKDGKFSQVTSN
ALDMKLRDDLERLKKIRNHRGLRHYWGLRVRGQHTKTTGRRG
Ligand information
>8auv Chain h (length=1626) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcauguguaaguaugaacaaauucagacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguaucuacuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucuggaagggau
gcauuuauuagauaugcgaugauucaugauaacucgacggaucgcacggc
cgccggcgacgcaucauucaaauuucugcccuaucaacuuucgaugguag
gauaguggccuaccaugguggugacgggugacggagaauuaggguucgau
uccggagagggagccugagaaacggcuaccacauccaaggaaggcagcag
gcgcgcaaauuacccaauccugacacggggagguagugacaauaaauaac
aauaccggcugguaauuggaaugaguacaaucuaaaucccuuaacgagga
uccauuggagggcaagucuggugccagcagccgcgguaauuccagcucca
auagcguauauuuaaguuguugcaguuaaaaagcucguaguuggacuuug
ggaugucccguuacuuugaagaaauuagagugcucaaagcaagccuacgc
ucuguauacauuagcaugggauaacauuauaggauuucgguccuauuucg
ggaucggaguaaugauuaacagggacagucgggggcauucguauuucaua
gucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaagca
uuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucgaag
acgaucagauaccguccuagucucaaccauaaacgaugccgaccagggau
cggcggauguugcuaggacuccgccggcaccuuaugagaaaucaaaguuu
uuggguuccggggggaguauggucgcaaggcugaaacuuaaaggaauuga
cggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacac
ggggaaacuuaccagguccagacauaguaaggauugacagacugagagcu
cuuucuugauucuaugggugguggugcauggccguucuuaguugguggag
cgauuugucugguuaauuccguuaacgaacgagaccucagccugcuaacu
agcuaugcggagguaucccuucgcggccagcuucuuagagggacuacggc
cuuuuaggccgcggaaguuugaggcaauaacaggucugugaugcccuuag
auguucugggccgcacgcgcgcuacacugauguauucaacgaguuuauag
ccuuggccgacaggcccggguaaucuuugaaauuucaucgugauggggau
agaucauugcaauuguuggucuucaacgaggaauuccuaguaagcgcgag
ucaucagcucgcguugacuacgucccugcccuuuguacacaccgcccguc
gcuccuaccgauugaaugauccggugaaauguucggaucgcgcgagaagu
ccauugaaccuuaucauuuagaggaaggagaagucguaacaagguuuccg
uaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>........<.<<<..<<...>>..>>>.>
....<<<<<<................>>>>>>.........<<<<.<<<<
.>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....<<<<<<<
<.......>>>>>>>>>>>......>>>...<<<.<<<<....>>>>...
.>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>
>>.........<<<....<<<.....>>>..>>>..>....>.>.....<
<<<<<<<..>>>>>.>>>......<<..<...........>..>>.....
....<<<<<((....<.<<<<.....<<..))>>.......>>>>>>>>>
>..>>>>>>>>>..........<.<((.....<.<<...<<<.<<.....
<<<..>>>.<<<<<<.<<.......<<...<.......>..<<<....>>
>.....>>......>>.>>..>>>>........<<<<<<<<<<<.....>
>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<<
<...<<<......>>>......>>>>>>>>..>>.......<<....>>.
..>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<
<<<.........>>>>...>>>>>>>>..........<<<.<<.<<<..<
<<<<<<<.<<<.<..>>>>>>>>>>>>..>>>...<<..))>>...>>..
...>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<.......<<........>
>..........<<<<<......<<<<<........<<.<<<........>
>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<..
....>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..
<<<<.<<<<<<<<....>>>>>>>>...>>>>..>>>>.>>.....<<<<
<.....>>>>>........>>>>>....>>>.>>>.....>>>>>>>...
....>>>>>....>.>>>>.>>>.....<<<<.<.......<<.......
<<<.<<<<....>>>>.>>>....>>.......>.>>>>......<....
<<<<<<..........>>>>>>....>.....>>>>>>....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
.<<<<<.<<....<<<<<<<..<<<..<<<<..<...<<<<>>>>...>.
.>>>>..>>>..>>>>>>>...>>.>>>>>..>.>>...>.....<<<<<
<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8auv Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Resolution2.38 Å
Binding residue
(original residue number in PDB)		K25 F28 G35 I36 G37 R39 F40 R55 W82 F83 N85 Q87 K88 Q97 L107 D110 H120 R121 H125 R130 V131 R132 G133 Q134 H135 T136 K137 T138 T139 G140 R141 R142 G143
Binding residue
(residue number reindexed from 1)		K24 F27 G34 I35 G36 R38 F39 R54 W81 F82 N84 Q86 K87 Q96 L106 D109 H119 R120 H124 R129 V130 R131 G132 Q133 H134 T135 K136 T137 T138 G139 R140 R141 G142
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8auv, PDBe:8auv, PDBj:8auv
PDBsum8auv
PubMed37156858
UniProtA0A1S3YM01

[Back to BioLiP]