Structure of PDB 8a3w Chain U Binding Site BS01

Receptor Information
>8a3w Chain U (length=114) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAVRAKVGSRSYVRQKQLAKGKKVFKIDCSIPADVLGNFEQFFQDNTKLN
GRKGKLSDKVRLSMNDNVLTISTTMAYRKKYFKYLTKKFLKKKDLRDWIR
ILATGKGTYQLKYF
Ligand information
>8a3w Chain 2 (length=947) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaauugccaacucagaa
cugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugau
gcauccaagugguguauaucgcaaacugauuucugcccagugcucuguca
acgugacgagauucaccgacgcgcggguaaacggcgggcucucuuaaggu
agccaaaugccucgucuuccaauuagagacgcgcaugaauggauuaauga
gauucccucugucccgaguuacuaucuagcgaaacgacagucaagggaac
ggacuugaagggcuaagcggggaaagaagacccuguugaguuugacucca
gucuggcucugugcgguucacuuaucgaaugaagagaccaauggguuuag
cguagucuggcuaugcaccgucuagguuccgugcuguaaacugaaccaac
gggaguuccggagucuuguuucgagacaucugccagauggggaguuuggc
uggggcggcauaucuguuacacgacaacgcagguguccuaaggcgagcuc
agugggaucucacguagaacacaagcguaaaagcuugcuugauuaacgau
uuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgau
gaacaaaucauaccagaggugucagaauaauuaccacagggauaaggcuu
gauccuucgaugucggcucuuccuaaccuagcggcuaaggguuggauugu
ucacccacugacagggaacgugagcuggguuuagaccgucgugagacagg
uugguuuuacccuacuuagcuggaaauugcgagaaaaauccguaagc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<..>>>>>..>>>>>>.
>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<...
.<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<<..
..<<<<......>>>>....>>..>>>>..>>>>><<....>>.......
.<...........<<<<<.......>>>>>.....>.....>>....>>.
>>>>>>>..>..>>.>>>>>>>>.>>>>............<<<<<.....
...>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.
<<<<<<<...<<<.<.>.>>>...<<<<<.....<<<<...........<
.<<<.........>>>.>...............................<
<<<...>>>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<
<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<..
.<<<<<..>>>>>.....<<......>>....>>>>>>>...<<...<<<
<<.......>>>>>..>>.<<<....>>>.>>.........<<<<<..<<
<.......>>>..>>>>>..........>>>>..>>>>>>.....<<.<.
>.>.>.......<<<<<.<<<<<<..<<<<<<.>>>..>>>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>.>>>>>>>..........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)
V2 A3 R5 K7 V8
Binding residue
(residue number reindexed from 1)
V1 A2 R4 K6 V7
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4Q0X2

[Back to BioLiP]