Structure of PDB 7uvz Chain U Binding Site BS01
Receptor Information
>7uvz Chain U (length=97) Species:
480119
(Acinetobacter baumannii AB0057) [
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ANFVLNAQARAEDKQGKGASRRLRRESLVPAIIYGGNAEPVAVTLELREL
VKALESNVFFEEVVEIKVGDKVENVKIQALQRHPAKNTPMHADFKRA
Ligand information
>7uvz Chain B (length=115) [
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gcuggcgaccauagcaagagugaaccaccugaucccuucccgaacucaga
agugaaaccucuuagcgcugaugguagugugggauuacccaugugagagu
aagucaucgccagcu
<<<<<<<<.....<<<<<<<.....<<<<<<...............>>>.
.>>>....>>>>>.>><<<.......<<<<<<<....>>>>>>>......
.>>>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
7uvz
Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome.
Resolution
2.21 Å
Binding residue
(original residue number in PDB)
R11 Q16 K18 S21 R22 R23 R25 R26 I33 Y35 Q79 Q82 H92
Binding residue
(residue number reindexed from 1)
R10 Q15 K17 S20 R21 R22 R24 R25 I32 Y34 Q78 Q81 H91
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0008097
5S rRNA binding
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:7uvz
,
PDBe:7uvz
,
PDBj:7uvz
PDBsum
7uvz
PubMed
37192172
UniProt
B7I7B6
|RL25_ACIB5 Large ribosomal subunit protein bL25 (Gene Name=rplY)
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