Structure of PDB 7unw Chain U Binding Site BS01

Receptor Information
>7unw Chain U (length=110) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEVAAKLSGARISAQKARLVADQIRGKKVGEALNLLAFSSKKAAEIMKKV
LESAVANAEHNEGADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRS
CHITVKVADK
Ligand information
>7unw Chain A (length=2884) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggucaagugaagaagcgcauacgguggaugccuuggcagucagaggcgau
gaaagacgugguagccugcgaaaagcuucggggagucggcaaacagacuu
ugauccggagaucucugaaugggggaacccaccuaggauaaccuagguau
cuuguacugaauccauaggugcaagaggcgaaccaggggaacugaaacau
cuaaguacccugaggaaaagaaaucaaccgagauucccuuaguaguggcg
agcgaacggggauuagcccuuaagcuucauugauuuuagcggaacgcucu
ggaaagugcggccauagugggugauagccccguacgcgaaaggaucuuug
aagugaaaucgaguaggacggagcacgagaaacuuugucugaacaugggg
ggaccauccuccaaggcuaaauacuacugacugaccgauagugaaccagu
accgugagggaaaggcgaaaagaaccccggagaggggagugaaauagaac
cugaaaccguaugcguacaagcagugggagccuacuuguuaggugacugc
guaccuuuuguauaaugggucagcgacuuauauucaguggcaagcuuaac
cguauaggguaggcguagcgaaagcgagucuuaauagggcguuuagucgc
uggguauagacccgaaaccgggcgaucuauccaugagcagguugaagguu
agguaacacugacuggaggaccgaacccacucccguugaaaagguagggg
augacuuguggaucggagugaaaggcuaaucaagcucggagauagcuggu
ucuccucgaaagcuauuuagguagcgccucauguaucacucuggggggua
gagcacuguuucggcuagggggucaucccgacuuaccaaaccgaugcaaa
cuccgaauacccagaagugccgagcaugggagacacacggcgggugcuaa
cguccgucgugaaaagggaaacaacccagaccgccagcuaaggucccaaa
guugugguuaagugguaaacgaugugggaaggcuuagacagcuaggaggu
uggcuuagaagcagccacccuuuaaagaaagcguaauagcucacuagucg
agucggccugcgcggaagauguaacggggcucaaaccacacaccgaagcu
gcgggugucacggugacgcgguagaggagcguucuguaagccugugaagg
ugaguugagaagcuugcuggagguaucagaagugcgaaugcugacaugag
uaacgacaaugggugugaaaaacacccacgccgaaagaccaaggguuccu
gcgcaacguuaaucgacgcaggguuagucgguuccuaaggcgaggcugaa
aagcguagucgaugggaaacagguuaauauuccuguacuucugguuacug
cgauggagggacggagaaggcuaggccagcuuggcguugguuguccaagu
uuaaggugguaggcugaaaucuuagguaaauccgggguuucaaggccgag
agcugaugacgagucgucuagaugacgaagugguugaugccaugcuucca
agaaaagcuucuaagcuucagguaaccaggaaccguaccccaaaccgaca
cagguggucggguagagaauaccaaggcgcuugagagaacucgggugaag
gaacuaggcaaaauggcaccguaacuucgggagaaggugcgccggcuagg
gugaaggauuuacuccguaagcucuggcuggucgaagauaccaggccgcu
gcgacuguuuauuaaaaacacagcacucugcaaacacgaaaguggacgua
uagggugugacgccugcccggugccggaagguuaauugaugggguuagcg
caagcgaagcucuugaucgaagccccgguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcacga
auggcguaacgauggcggcgcugucuccacccgagacucagugaaauuga
aaucgcugugaagaugcaguguauccgcggcuagacggaaagaccccgug
aaccuuuacuguagcuuugcacuggacuuugagccugcuuguguaggaua
ggugggaggcuuugaagcguggacgccaguucgcguggagccauccuuga
aauaccacccuggcaugcuugagguucuaacucugguccguaauccggau
cgaggacaguguauggugggcaguuugacuggggcggucuccuccuaaag
aguaacggaggaguacgaaggugcgcucagaccggucggaaaucggucgc
agaguauaaaggcaaaagcgcgcuugacugcgagacagacacgucgagca
gguacgaaaguaggucuuagugauccggugguucuguauggaagggccau
cgcucaacggauaaaagguacuccggggauaacaggcugauaccgcccaa
gaguucauaucgacggcgguguuuggcaccucgaugucggcucaucacau
ccuggggcugaagccggucccaaggguauggcuguucgccauuuaaagug
guacgcgagcuggguuuagaacgucgugagacaguucggucccuaucugc
cguggacguuugagauuugagaggggcugcuccuaguacgagaggaccgg
aguggacgaaccucugguguuccgguugucacgccaguggcauugccggg
uagcuauguucggaaaagauaaccgcugaaagcaucuaagcgggaaacuu
gccucaagaugagaucucacugggaacuugauuccccugaagggccgucg
aagacuacgacguugauaggcuggguguguaagcguugugaggcguugag
cuaaccaguacuaauugcccgugaggcuugacca
<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<.[[.(((.>>>.....<<<<<<<..<<<)))..]].>>>..
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>...<<<<<.....<<....
.>>....>>>>>...(((.....<<<<<<..<<<<<..<<<...<<<.<.
.....>.>>>((......<<<.....))>>>...>>>....>>>>>..>>
>>>>...........<<<<<<<<.........>>>>>>>>......<<<<
<..<<<<>>>>>..)))......]].>>>>>>>.]]..............
.<<....>>....]].........<<<<.....>>>>.............
.....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>
...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<
<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>
>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<
<<......>>>>>>.....>>>...<<<.<<.<<........>>.>>>>>
....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>.
.<<<<<<....<<<<<....>>>>>.<<<<<<<<..<<<<<<<<<.....
<<<...<<<.<<<<...<<................>>...>>>>.>>>..
>>.>.....>>>>>>.>>>....>>>>>>>.>...<<<<<<<<<<.....
.>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((...
..<<<<<<...........<<..<<<<<..<<........<<<<<.<<..
.<<<<.......>>>>...>>........<<........>>..>>>>>..
..>>..>>>>>.>>...........)))......>>>>>>.>>>...>>>
>>>><<<<<<<.>>>>>>>....>>>>>><.<<<<<...<<<......<<
<<<<<<....>>>>>>>>...>>>..>>>>>..>.....>>>>>><....
..<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<<<<...<<<...<<<...
.>>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<<<<
<...<<<<....<<<<..<<<..<<<<<<<<<<<...((((...>>>>>>
<<..<<<....<<<<<<<<<<<..<<.....>>.>>>>>>>..>>>>...
.>>>...>><..<<<<<<..>>>>>>...>>>>>>...>>>...>>>.>.
.......>>>>...>>....>>>>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<
...............<<<<<.....<..>......>>>>><<<<<<<<<<
<<...<<<.....>>>....>>>>>>>>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<<....>>>......
.>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<.......<<<<<<.<<.
...>>..>>>>>>.......>>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<<.....>>>>>>.....>..
..>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<.<.<............
<<<<...<<............<<<....>>>.........>>........
.....>>>>...>.>.>>>>>>>>>>>...<<<.<<<<<<.....>>>>>
>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<.....
......>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>..
...<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>
>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>
>>.............>>>>..]]>>>>.......<<<<.<.<<<<<<...
<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..
<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>
>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>
>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>
>>>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>.
..>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>
.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<<<<<<<<
.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>
>...>>>>>.>>>...>>>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7unw Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
Resolution2.6 Å
Binding residue
(original residue number in PDB)		K6 L7 S8 S13 Q15 K16 R18 R25 K41 K42 K49 A56 N57 H60 N61 N77 E78 R80 K83 R84 M86 P87 R88 A89 K90 G91 R92 A93 D94 V97 K98 H102
Binding residue
(residue number reindexed from 1)		K6 L7 S8 S13 Q15 K16 R18 R25 K41 K42 K49 A56 N57 H60 N61 N77 E78 R80 K83 R84 M86 P87 R88 A89 K90 G91 R92 A93 D94 V97 K98 H102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7unw, PDBe:7unw, PDBj:7unw
PDBsum7unw
PubMed
UniProtA0A1T1HVZ5

[Back to BioLiP]