Structure of PDB 6wdr Chain U Binding Site BS01

Receptor Information
>6wdr Chain U (length=103) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTR
KTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVV
ASN
Ligand information
>6wdr Chain 2 (length=1647) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguug
gccggucggauuuccaacggggccuuuccuucuggcuaaccuugaguccu
uguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcguauugcucgaauauauuagcauggaauaauagaauaggac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcauaacuacugcgaaagcauuugccaaggacguuuucau
uaaucuaaccauaaacuaugccgacuagggaucgggugguguuuuuuuaa
ugacccacucggcaccuuacgagaaaucaaagucuuuggguucugggggg
aguauggucgcaaggaugaaacuuaaaggaauugacggaagggcaccacc
aggaguggagccugcggcuuaauuugacucaacacggggaaacucaccag
guccagacacaauaaggauugacagauugagagcucuuucuugauuuugu
gggugguggugcauggccguucuuaguugguggagugauuugucugcuua
auugcgauaacgaacgagaccuuaaccuacuaaauaguggugcuagcauu
ugcugguuauccacuucuuagagggacuaucgguuucaagccgauggaag
uuugaggcaauaacaggucugugaugcccuuagacguucugggccgcacg
cgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuug
guaaucuugugaaacuccgucgugcuggggauagagcauuguaauuauug
cucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguugau
uacgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaaug
gcuuagugaggccucaggaucugcuuagagaagggggcaacuccaucuca
gagcggagaauuuggacaaacuuggucauuuagaggaacuaaaaguc
..<<<<<...((((>>>>><<<<.<<<<.....<.<...<.......<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<..<<..<<....<<<..................<.....<<.
<<.......>>.>>......>.........<<<<<..<......>..>>>
>><...<<<<<<......(((.(((.........................
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>..........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<.<.......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.........)).........>>>>.>>>>>....>>>>>
>>>.........<<.<<................<<....<<<<<<.<<<<
<............>>>>>.>>>>>>.....<<<<<.....<..<<<<...
....>>>>..>.....>>>>>....<<<<<.<<.......<<...<....
...>..<<<.....>>>....>>......>>.>>..>>>.........<<
<..<<<<.<<......))).)))..>>.>>>>.>>>.....>>....<<<
<<<.<<...<<<<........<<....>>...>>>>...>>>>>.>>>..
....................((.((.<<<..<<<<<<<<.<<<.<....>
.>>>>>>>>>>>..>>>...((..>>))...)).....))...>>.<<<.
.......<......>......>>>..)))).....<..<<<<<<......
...<<<..<<..............<<........>>..........<<<<
<......<.<<............<............>..........>>.
.>..................<....<<<.<<<<......>>...<<<...
...>>>...>>.>>>....<<<<..<<..<<<<..<<<<<...<<<....
..>>>.....>>>>>..>>>>.>>....<<<<<<.....>>>>>>.....
...>>>>....>.........................>>>>>........
....>>.....<<<<<<<......<<.....<<..<<<<....>>>>..>
>....>>.......>>>>>>>...........<<<<<<..........>>
>>>>..........>>>.......<<<<...............>>>>...
.........>>>>>>.>.................<<<<.....<<<<<<<
<<<.<<<..<.<<..<...<<<<<<<.<<....<<<....>>>....>>.
>>>>>>>...>..>>.>..>>>.>>>>>>>>>>....>>>>......
Receptor-Ligand Complex Structure
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PDB6wdr An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R23 K53 G54 R57 L58 P59 T67 R68 K69 T70 P71 G73 E74 S76 W79 R85 H87 K88 Y90
Binding residue
(residue number reindexed from 1)		R5 K35 G36 R39 L40 P41 T49 R50 K51 T52 P53 G55 E56 S58 W61 R67 H69 K70 Y72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wdr, PDBe:6wdr, PDBj:6wdr
PDBsum6wdr
PubMed33219089
UniProtP38701|RS20_YEAST Small ribosomal subunit protein uS10 (Gene Name=RPS20)

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