Structure of PDB 6l56 Chain U Binding Site BS01

Receptor Information
>6l56 Chain U (length=169) Species: 220873 (Tegillarca granosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTQPRQNFHVESEAGINKQINMELYASYVYQSMYMYFDRDDVALPSFAKY
FKHNSEEEREHAEKLMKYQNKRGGRIVLQDIQKPDLDEWGSPLEAMQTTL
ALEKSVNQALLDLHKIADKHGDAQMMDFLEGEYLKEQVDAIEEISDHITN
LKRVGTGLGEYMYDKETMS
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain6l56 Chain U Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6l56 Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa.
Resolution1.85301 Å
Binding residue
(original residue number in PDB)		E25 E60 H63
Binding residue
(residue number reindexed from 1)		E23 E58 H61
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6l56, PDBe:6l56, PDBj:6l56
PDBsum6l56
PubMed35359603
UniProtD3JCC5

[Back to BioLiP]