Structure of PDB 6gmh Chain U Binding Site BS01

Receptor Information
>6gmh Chain U (length=110) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG
GGGGGGGGGG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gmh Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		X528 X529
Binding residue
(residue number reindexed from 1)		X109 X110
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding
Biological Process
GO:0001711 endodermal cell fate commitment
GO:0006368 transcription elongation by RNA polymerase II
GO:0016055 Wnt signaling pathway
GO:0019827 stem cell population maintenance
GO:0031124 mRNA 3'-end processing
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0016593 Cdc73/Paf1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gmh, PDBe:6gmh, PDBj:6gmh
PDBsum6gmh
PubMed30135578
UniProtQ8WVC0|LEO1_HUMAN RNA polymerase-associated protein LEO1 (Gene Name=LEO1)

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