Structure of PDB 5zwn Chain U Binding Site BS01

Receptor Information
>5zwn Chain U (length=583) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALRGLDTQFLQDNTALVQAYRGLDWSDISSLTQMVDVIEQTVVKYGNPND
SIKLALETILWQILRKYPLLFGFWKRFATIEYQLFGLKKSIAVLATSVKW
FPTSLELWCDYLNVLCVNNPNETDFIRNNFEIAKDLIGKQFLSHPFWDKF
IEFEVGQKNWHNVQRIYEYIIEVPLHQYARFFTSYKKFLNEKNLKTTRNI
DIVLRKTQTTVNEIWQFESKIKQPFFNLGQVLNDDLENWSRYLYHENTWM
MYIKWLTKKNISDEVVVDIYQKANTFLPLDFKTLRYDFLRFLKRKYRSNN
TLFNNIFNETVSRYLKIWPNDILLMTEYLCMLKRHSFKNSLDQSPKEILE
KQTSFTKILETSITNYINNQIDAKVHLQTLINDKNLSIVVVELIKTTWLV
LKNNMQTRKYFNLYQKNILIKNSVPFWLTYYKFEKSNVNFTKLNKFIREL
GVEIYLPTTVMNDILTDYKTFYLTHSNIVTYESSIIDSNTFDPILYPELK
MSNPKYDPVLNTTANVDWHKKTEWKEAGHIGITTERPQISNSIIECNSGT
LIQKPISLPNFRNLEKINQVKINDLYTEEFLKE
Ligand information
>5zwn Chain P (length=480) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggaaaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuaguucauugaa
gucauugaugcaaacuccuuggucacacacacggcgcggaaggcguguuu
gcugacguuuccauucccuuguuucaaucauugguuaaucccuuuggguu
aaacugauuuuuggggcccuuuguuucuucugccuggagaaguuugacac
caaauucaaauugguguuaggggagcuggggccuuucaaaagagcuuugu
agaggcauucuuuuugacuacuuuucgcgugccauuuuaguuuuugacga
uucgaaugaacuaguuuaugaugaaguugagauuauuuggucgauuguag
uuugaagauguagucucaacuuugcucaaauuuuggaaggucuugguagg
aacggguggaucuuauaauuuuugauuuau
...........<<<<.<<<<<<<<.....>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<<..>>>>>.>>>.
......>>>>>.>>>>>>>>.................>>>>>>>>>>>>>
><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<.<.<<<...>>>.>
.>>>>>>>..>>>>>>>((.......<<<<<....))>>>>>...<<<<<
<<<.......>>>>>>>>.>>>>><<<<<<<<<<<<<<<<<..<<...<<
.<<<<<..<<<<<..<<<<<<..<<.....<<<<...<<<<<<..<<<..
<<<<.<<<<<<<>>>>>>>..>>>>>>>.>>>>>>..>>>>.>>..>>>>
>>.>>>>>....>>>>>.>>...>>.....>>>>>>>>>>>>>>>>>.>>
>>>>..>>>.>>>>................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zwn Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.4 Å
Binding residue
(original residue number in PDB)		I596 Q597
Binding residue
(residue number reindexed from 1)		I552 Q553
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030627 pre-mRNA 5'-splice site binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0071004 U2-type prespliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwn, PDBe:5zwn, PDBj:5zwn
PDBsum5zwn
PubMed29794219
UniProtP39682|PRP39_YEAST Pre-mRNA-processing factor 39 (Gene Name=PRP39)

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