Structure of PDB 5ll6 Chain U Binding Site BS01

Receptor Information

>5ll6 Chain U (length=184) Species: 4932 (Saccharomyces cerevisiae)

PQAKILSQAPTELELQVAQAFVELENSSPELKAELRPLQFKSIREIDVAG
GKKALAIFVPVPSLAGFHKVQTKLTRELEKKFQDRHVIFLAERRILPKPS
RTSRQVQKRPRSRTLTAVHDKILEDLVFPTEIVGKRVRYLVGGNKIQKVL
LDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPS

Ligand information

>5ll6 Chain 2 (length=1325)

uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccggucggauuuccaacggggccuuuccuucuggcuaaccuugagucc
uuguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguu
caaagcaggcguauugcucgaauauauuagcauggaauaauagaauagga
cguuugguucuauuuuguugguuucuaggaccaucguaaugauuaauagg
gacggucgggggcaucaguauucaauugucagaggugaaauucuuggauu
uauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaa
ucaagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucu
uaaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugacc
cacucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguau
ggucgcaaggcugaaacuuaaaggaauugacggaagguugguggagugau
uugucugauaacgcccuuuguacacaccgcccgucgcuaguaccgauuga
auggcuuagugaggccucaggaucugcuuagagaucucagagcggagaau
uuggacaaacuuggucauuuagaggaacuaaaagucguaacaagguuucc
guaggugaaccugcggaaggaucau

...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[..................<<....<<
.<<<.....>>>.>>.....>>.........<<<<<..<<....>>..>>
>>>[...((((((......<<<<<<<.<<<....>>>.............
.)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}
}}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.......
...>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<
.....>>>..>>>...............<<<<<<<<..<<......>>..
>>>>>.>>>......<<..<...........>..>>.........<<<<<
((......<<<<.....<<..))>>.......>>>>.>>>>>..))))))
]]]].........[[[<<.......{{...[[[.[[....<<<<<<.<<<
<<............>>>>>.>>>>>>....<<<<<...............
..................>>>>>...<<<<<.<<.......<<...<...
....>..<<<.....>>>....>>......>>.>>..>>>.........[
....(((((((......>>>>>>>..)))))))...].....]]....<<
<<<<.<<...<<<<..<<<.<<<<<<.<...<<<......>>>......>
.>>>>>>.>>>.......<<....>>...>>>>...>>>>>.>>>...]]
]...}}......<<<<<<<...<...<<<<.........>>>>...>>>>
>>>>..........<<<.<<.<<<..<<<<<<<<.<<<........>>>>
>>>>>>>..>>>...<<..>>>>...>>.....>>>.]]].<<<......
<<<<....>>>>....>>>..]]]]..<<<<<.<<<<...<<<<......
>>........>>..>>>>>>>.>>....<..<<.<..<<<<.<<....<<
<<<<<<.<<<..<.<<..<...<<<<<<<..........>>>>>>>...>
..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<
<<<<<....>>>>>>>>>.......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5ll6 Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): P63 E95 R96 R97 I98 P100 K101 R104 R107 Q108 Q110 K111 R112 P113 R114 R116 T117 L118 T177
• Binding residue (residue number reindexed from 1): P60 E92 R93 R94 I95 P97 K98 R101 R104 Q105 Q107 K108 R109 P110 R111 R113 T114 L115 T174

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006364 rRNA processing
• GO:0006412 translation
• GO:0042254 ribosome biogenesis
• GO:0042274 ribosomal small subunit biogenesis

Cellular Component

• GO:0005634 nucleus
• GO:0005654 nucleoplasm
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:0030686 90S preribosome
• GO:0032040 small-subunit processome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5ll6, PDBe:5ll6, PDBj:5ll6
• PDBsum: 5ll6
• PubMed: 28368393
• UniProt: P26786|RS7A_YEAST Small ribosomal subunit protein eS7A (Gene Name=RPS7A)