Structure of PDB 4ozt Chain U Binding Site BS01

Receptor Information
>4ozt Chain U (length=195) Species: 121224 (Pediculus humanus corporis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NAVANICQATNSQLYQLVEWAKHIPHFSSLPIEDQVLLLRAGWNELLIAA
FSHRSVEVRDGIVLGAGITVHRNSAHQAGVGTIFDRVLTELVAKMRDMNM
DRTELGSLRSIILFNPEVRGLKSGQEVELLREKVYAALEEYTRVTRPEEP
GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDIPIDTFLMDMLGS
Ligand information
Ligand IDNEQ
InChIInChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChIKeyHDFGOPSGAURCEO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCN1C(=O)C=CC1=O
ACDLabs 10.04O=C1C=CC(=O)N1CC
FormulaC6 H7 N O2
NameN-ETHYLMALEIMIDE
ChEMBLCHEMBL8211
DrugBankDB02967
ZINCZINC000000901367
PDB chain4ozt Chain U Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ozt Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		T277 E367
Binding residue
(residue number reindexed from 1)		T82 E172
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ozt, PDBe:4ozt, PDBj:4ozt
PDBsum4ozt
PubMed25004972
UniProtE0VFQ5

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