Structure of PDB 7r81 Chain T2 Binding Site BS01

Receptor Information
>7r81 Chain T2 (length=141) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNHILRLLNTNVDGKQKVVYSLTKIKGVGRRYSNLVCKKADVDLSKRAGE
LTSEELERIVTIMQNPTAYKIPAWFLNRQRDIVDGKDSQILANGVDSKLR
DDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVGVS
Ligand information
>7r81 Chain A2 (length=1769) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauucugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguuuaagcaauuaaaccgcgaaacugcgaauggcucau
uaaaucaguuauaguuuauuugauaguaccuuacuacauggauaaccgug
guaauucuagagcuaauacaugcuaaaaaccccgacuucagggguguauu
uauuagauuaaaaaccaaugcccuucggggcuaacuggugauucauaaua
acuucucgaaucgcauggccuugcgcuggcgaugguucauucaaauuucu
gcccuaucaacuuucgacggcugggucuuggccagccauggugacaacgg
guaacggaggguuagggcucgaccccggagaaggagccugagaaacggcu
acuacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacg
gggagguagugacaauaaauacugauacagggcucuuuugggucuuguaa
uuggaaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaa
gucuggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugagguuaaaaagcucguaguugaaccuugggcucggcccgucgg
uccugggucgggccuuuccuggagaaccgcaugcccuucacugggugugu
cggggaaccaggacuuuuaccgugaacaaaucagaucgcucaaagaaggc
cuaugcucgaauguacuagcauggaauaauagaauaggacgugugguucu
auuuuguugguuucuaggaccgccguaaugauuaauagggacagucgggg
gcaucaguauucaauugucagaggugaaauucuuggauuuauugaagacu
aacuacugcgaaagcauuugccaaggauguuuucauuaaucaggaacgaa
aguuaggggaucgaagacgaucagauaccgucguagucuuaaccauaaac
uaugccgauuagggaucggacgguguuauuuuuugacccguucggcaccu
uacgauaaaucaaaauguuugggcuccugggggaguauggucgcaaggcu
gaaacuuaaagaaauugacggaagggcaccaccagggguggagccugcgg
cuuaauuugacucaacacggggaaacucaccagguccagacacgaugagg
auugacagauugagagcucuuucuugauuucgugggugguggugcauggc
cguucuuaguugguggagugauuugucugcuuaauugcgauaacgaacga
gaccuuaaccugcuaaauagcccguauugcuuuggcaguacgcuggcuuc
uuagagggacuaucggcucaagccgauggaaguuugaggcaauaacaggu
cugugaugcccuuagauguucugggccgcacgcgcgcuacacugacacag
ccagcgaguacucccuuggccggaagguccggguaaucuuguuaaacugu
gucgugcuggggauagagcauugcaauuauugcucuucaacgaggaaucc
cuaguaagcgcaagucaucagcuugcguugauuacgucccugcccuuugu
acacaccgcccgucgcuacuaccgauugaauggcucagugaggcuuccgg
acuggcccagggaggucggcaacgaccacccagggccggaaagcuaucca
aacucggucauuuagaggaaguaaaagucguaacaaggucuccguuggug
aaccagcggagggaucauu
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<<...<<.........>>..>>>.>>......<<...
.....<<<..<<..<<....<<<...............<<.....<..<<
<.....>>>..>......>>........<<<<<.......>>>>><...<
<<<<<......[.......<<<<....>>>>..............>>>>>
>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>
>.<<<....<<<......<<<<<<.......>>>>>>..>>>......>>
>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>
.>>.<.<<<..>>>.>...>>>>>>.........<<<....<<<<...>>
>>..>>>..>....>.>....<<<<.<<<<<<..........>>>>>>..
>>>>.....<<..<...........>..>>.........<<<<<((....
..<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>..
.......<<<((.....<.<<...<<<.<<....<<<<<<<<<<<<....
...>>>>>>>>>>>>..<<<..............................
.........>>>....<<<<<<<<.......<<..<<.......>>.<<<
....>>>....>>......>>>>>..>>>.........<<<.<<<<<<<<
<...........].>>>>>>>>>>>>.....>>....<<<<<<.<<...<
<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..>>
.......<<....>>...>>>>...>>>>>.>>>...>>>...>>.>...
.<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.......
...<<<.<<.<<<..<<<<<<<<.<<<<.....>>>>>>>>>>>>..>>>
...<<..))>>...>>.....>>>.>>>.<<<......<<<<....>>>>
....>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<..<<<.
.......<<........>>..........<<<<<<.....<<<<<.....
...<<.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<
<<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>..
..<<<<<.<<..<<<<..<<<<..<<<..........>>>....>>>>..
>>>>.>>....<<<<<<....>>>>>>.......>>>>>....>>>.>>>
.....>>>>>>>.....>>>.>>>......>>>..>>>.....<<<<<<<
......<<.....<<<.<<<<....>>>>.>>>....>>.......>>>>
>>>......<....<<<<<<..........>>>>>>....>.....>>>>
>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>
.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<.<..<..
.<<<<<<<.<<<.<<<<<....>>>>>.>>>.>>>>>>>...>..>.>>.
.>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<.
.>>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r81 Structure of the translating Neurospora ribosome arrested by cycloheximide
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Q26 K27 Y30 K36 G37 V38 G39 R40 R41 Y42 R57 W84 F85 N87 R88 Q89 H122 R123 H127 R132 V133 R134 G135 Q136 H137 T138 K139 T140 T141 G142 R143 R144 G145 R146 V148
Binding residue
(residue number reindexed from 1)		Q16 K17 Y20 K26 G27 V28 G29 R30 R31 Y32 R47 W74 F75 N77 R78 Q79 H112 R113 H117 R122 V123 R124 G125 Q126 H127 T128 K129 T130 T131 G132 R133 R134 G135 R136 V138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7r81, PDBe:7r81, PDBj:7r81
PDBsum7r81
PubMed34815343
UniProtQ7RXX0

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