Structure of PDB 7oyb Chain T2 Binding Site BS01

Receptor Information
>7oyb Chain T2 (length=137) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDENWFYI
RAASTVRHLYLRGGVGVGSMTKIYGGRKRNGVCPSHFSVGSKNVARKVLQ
ALEGLKMVEKDPNGGRRLTPQGTRDLDRIAGQVAAAS
Ligand information
>7oyb Chain 22 (length=1502) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguaauauaugcuugucucaaagauuaagcca
ugcaagucuaagugcacacgagugaaacugcgaauggcucauuaaaucag
uuaugguuccuuugaucacuuggauaacuguggcaauuccagagcuaaua
caugcgccgcgugcauuuaucaguggugacucuagauaacgccgaucgcg
cgcgcggcgacgguucauucgaaugucugcccuaucaacuuucgauggua
gguccgucgccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccauuuccgacacggagagguagugacgaaaaauaa
caauuuggaaugagugcaucccaaacccaugggcgaggacccauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaugc
uaacguugcugcaguuaaaaagcucguaguuggaucucuuuacuuugaaa
aaauuagaguguucaaggcagggccccccauugaauaccccagcuaggaa
uaauggaauaggaccccggggccaugaucgagagggacggccgggggcau
ucguauugcgccgcuagaggugaaauucuuggaccggcgcaagacggacc
ggagcgaaagcguuugccaagaacguuuucauuaaucaagaacgaaaguc
ggagguucgaagacgaucagauaccgucguaguuccgaccguaaacgaug
ccgacccgcgauccggcggcguuugacccgccgggcagcguugcgggaaa
ccacgagucucugggcuccggggggaguaugguugcaaagcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcuuaauuu
gacucaacacggggaaccucacccggcccggacaauugacagauucucga
uucugugggugguggugcauggccguucguaguugguggagcgauuuguc
ugguugauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcg
gccggucggcguaacuucuuagagggacaaguggcguucagccacgcgag
acugagcaauaacaggucugugaugcccuuagauguccggggcugcacgc
gcgccacaaugggcggaucaacguguccugcgccgacaggcgcggguaac
ccguugaaccccgcccgugauggggaccgauugaaacuauuucccgagaa
cgaggaauucccaguaagcgcaggucaucagcuugcguugauuaaguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugagcggcucagug
agguccucggaucggcgccgagaagacgaucgaacucggucguuuagagg
aaguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucau
ua
...<<<<<.[.((((>>>>><<.<<<<<<<...<.<<..<......<<<.
<<<..<<....<<.............>>.>>......<<........<<<
.<<<..<<....<..<....<<.....<<.<<<.....>>>.>>......
>>..............<<<<<...<......>..>>>>>......<<<..
<....>.>>>..>...>...>>>>>.>>>.<<<....<<<.....<<<<<
<<.......>>>>>>>.>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>
>>>.........<<<....<<<.....>>>..>>>..>...>>.>.....
<<...>>......<<.<<<.........>>>.>>.........<.<<<((
......<<<......<<..))>>........>>>.>>>.>..>>>>>>>.
>>.........<.<((.....<.<<...<<<.<<.....<<<<<<.<...
....<<...<.......>...<<...>>.......>>......>.>>>..
>>>..........<<<..>>>......>>....<<<<<<..<...<<<<.
.<<..<<<<<<<<...<<<......>>>......>>>>>>>.>.>>....
...<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.........>>>>...>>>>>>>>..........<
<<.<<.<<<..<<<<<<<<.<<<.>>>>>>>>>>>..>>>....<<..))
>>....>>.....>>>.>.>.<<<......<<<......>>>....>>>.
.)))).]<<<<<.<<<<<<<..<<..<<<<<....<<............<
<........>>..........<<.<<...........<<.....>>....
........<.<..<<<..<<.<<<<<<....<<<.<<<<<....>>>...
<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<..<<<
<<..>>>.>>..>>>>..>>>>..>.....<<<<<.....>>>>>.....
...>>>....>>>.>>>.....>>>>>.>>......>>.>>.........
>.>.......<<<<<<........<.<<<<<<<<....>>>>>>>>....
>.........>>>>>>............<<..........>>........
......>>>>>.....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<.<<...<<<<..>>>>...>>.>>>>..>>>.>>>>>>>>...>>
.>>>>...>.>>.........<<<<<<<<<<..>>>>>>>>>>.......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oyb A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K8 Q13 V35 V38 K39 L40 K42 K44 E45 L46 P48 C49 I56 S60 R63 R68 V71 G72 V73 G74 S75 K78 I79 G81 G82 R83 R85 G87 V88 C89 P90 S91 H92 F93 K98 N99 R102 Q106 K116 P118 G120 R123 R130 D133
Binding residue
(residue number reindexed from 1)		K2 Q7 V29 V32 K33 L34 K36 K38 E39 L40 P42 C43 I50 S54 R57 R62 V65 G66 V67 G68 S69 K72 I73 G75 G76 R77 R79 G81 V82 C83 P84 S85 H86 F87 K92 N93 R96 Q100 K110 P112 G114 R117 R124 D127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
GO:0030218 erythrocyte differentiation
GO:0035284 brain segmentation
GO:0042541 hemoglobin biosynthetic process
GO:0043009 chordate embryonic development
GO:0045088 regulation of innate immune response
GO:0045646 regulation of erythrocyte differentiation
GO:0048821 erythrocyte development
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oyb, PDBe:7oyb, PDBj:7oyb
PDBsum7oyb
PubMed36653451
UniProtA0A0R4IJ49

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