Structure of PDB 8ro2 Chain T Binding Site BS01

Receptor Information
>8ro2 Chain T (length=360) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYTMPKPQW
HPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSA
VYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQA
AEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASG
SPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWD
WRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYR
EDDTATEETH
Ligand information
>8ro2 Chain 5 (length=92) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuucucuucagaucgcauaaaucuuucgccuuuuacuaaagauuuccgu
ggagaggaacaccaauuuuuugagccuugccuuggcaaggcu
<<<<<<<<<<<........<<<<<<<<.<.......>.>>>>>>>>...>
>>>>>>>>>>............<<<<<<<<....>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
Y277 K279
Binding residue
(residue number reindexed from 1)
Y137 K139
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtO43660|PLRG1_HUMAN Pleiotropic regulator 1 (Gene Name=PLRG1)

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