Structure of PDB 8csq Chain T Binding Site BS01

Receptor Information
>8csq Chain T (length=164) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFN
IPQIQYKNPWVQIMMFKNMTPSPFLRFYLDSGEQVLVDVETKSNKEIMEH
IRKILGKNEETLREEEEEKKQLSHPANFGPRKYCLRECICEVEGQVPCPS
LVPLPKEMRGKYKA
Ligand information
>8csq Chain A (length=802) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaaaaauagacuacgaaaguggcuuuaacauau
cugaacacacaauagcuaagacccaaacugggauuagauaccccacuaug
cuuagcaacaguuaaaucaacaaaacugcucgccagaacacuacgagcca
cagcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggag
ccuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucag
ccuauauaccgccaucuuaacccugaugaaggcuacaaaguacguuaggu
caagguguagcccaugagguggcaagaaaugggcuacauuuucuacccca
gaaaauuuagcaguaaacugagaggcuuaguugaacagggcccugaagcg
cgucgucacccuccucaaguauacuucaaaggacauuuaacuaaaacccc
uacgcauuuauauagaggagacaagucguaaaguguacuggaaagugcac
uu
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<..<.<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>>........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<..............<<....>>.>>>>>>.....>
>>>...>>>>.....<<<<<...<<...<<<<.........>>>>...>>
>>>>>.<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<..
..>>>>.....>>..>>>>>>.....<<<<<<<<...<<<.<<<<<.<<<
<<<<<<<<......<<................>>.<<<<<<<.......<
<.<<<..<<<<<<<.<...<<<<<.....>>>.......>>..>.>.>>>
...>>>>>>>>....>>>>>>>..>>>.>>>>>>>.>...<<<<.....>
>>>..>>>>>.....<<<<<<<...>>>>>>>.....>>>...>>>>>>>
>..<<.....<<<<<<..<<<<<......<<<...<<<.....>>>..>>
>.......>>>>>.>>>>>>......>>..<<<<<<<<<....>>>>>>>
>>
Receptor-Ligand Complex Structure
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PDB8csq Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.54 Å
Binding residue
(original residue number in PDB)
P2 M3 K4 G5 R6 R11 T36 H37 K68 P131 Y134 C135 P150 S151 R160 G161 K162
Binding residue
(residue number reindexed from 1)
P1 M2 K3 G4 R5 R10 T35 H36 K67 P130 Y133 C134 P149 S150 R159 G160 K161
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8csq, PDBe:8csq, PDBj:8csq
PDBsum8csq
PubMed36482135
UniProtP82663|RT25_HUMAN Small ribosomal subunit protein mS25 (Gene Name=MRPS25)

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