Structure of PDB 8a3w Chain T Binding Site BS01

Receptor Information
>8a3w Chain T (length=152) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
THYSRKPQVSSKSAKAKVSDLRCHYKNTFETANVINGMPLRKAQQLYRQV
LAKTRCIPFKRYNGKIGRTAQAKEWGQTKGRWPRKSVVAMMSLLKNAEAN
AIEKGLDPNQMVIKHVQVDQAARMRRRTYRAHGRITPYMCSPCHVQLFMS
EK
Ligand information
>8a3w Chain 2 (length=947) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaauugccaacucagaa
cugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugau
gcauccaagugguguauaucgcaaacugauuucugcccagugcucuguca
acgugacgagauucaccgacgcgcggguaaacggcgggcucucuuaaggu
agccaaaugccucgucuuccaauuagagacgcgcaugaauggauuaauga
gauucccucugucccgaguuacuaucuagcgaaacgacagucaagggaac
ggacuugaagggcuaagcggggaaagaagacccuguugaguuugacucca
gucuggcucugugcgguucacuuaucgaaugaagagaccaauggguuuag
cguagucuggcuaugcaccgucuagguuccgugcuguaaacugaaccaac
gggaguuccggagucuuguuucgagacaucugccagauggggaguuuggc
uggggcggcauaucuguuacacgacaacgcagguguccuaaggcgagcuc
agugggaucucacguagaacacaagcguaaaagcuugcuugauuaacgau
uuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgau
gaacaaaucauaccagaggugucagaauaauuaccacagggauaaggcuu
gauccuucgaugucggcucuuccuaaccuagcggcuaaggguuggauugu
ucacccacugacagggaacgugagcuggguuuagaccgucgugagacagg
uugguuuuacccuacuuagcuggaaauugcgagaaaaauccguaagc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<..>>>>>..>>>>>>.
>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<...
.<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<<..
..<<<<......>>>>....>>..>>>>..>>>>><<....>>.......
.<...........<<<<<.......>>>>>.....>.....>>....>>.
>>>>>>>..>..>>.>>>>>>>>.>>>>............<<<<<.....
...>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.
<<<<<<<...<<<.<.>.>>>...<<<<<.....<<<<...........<
.<<<.........>>>.>...............................<
<<<...>>>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<
<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<..
.<<<<<..>>>>>.....<<......>>....>>>>>>>...<<...<<<
<<.......>>>>>..>>.<<<....>>>.>>.........<<<<<..<<
<.......>>>..>>>>>..........>>>>..>>>>>>.....<<.<.
>.>.>.......<<<<<.<<<<<<..<<<<<<.>>>..>>>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>.>>>>>>>..........................
Receptor-Ligand Complex Structure
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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)
H25 K66 G68 R69 K80 R82 W83 R85 K86 Y130 G134 I136 T137 P138 Y139 M140
Binding residue
(residue number reindexed from 1)
H24 K65 G67 R68 K79 R81 W82 R84 K85 Y129 G133 I135 T136 P137 Y138 M139
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4QAX6

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