Structure of PDB 7pir Chain T Binding Site BS01

Receptor Information

>7pir Chain T (length=53) Species: 272634 (Mycoplasmoides pneumoniae M129)

EVKNDDLELALKKFKRVSLEIRRLAQRHEYHLRKGMRLREKRKIAQKKRR
KFR

Ligand information

>7pir Chain 5 (length=1493)

ucugagaguuugauccuggcucaggauuaacgcuggcggcaugccuaaua
caugcaagucgaucgaaaguaguaauacuuuagaggcgaacgggugagua
acacguauccaaucuaccuuauaaugggggauaacuaguugaaagacuag
cuaauaccgcauaagaacuuugguucgaaucaaaguugaaaggaccugca
aggguucguuauuugaugagggugcgccauaucagcuaguugguggggua
acggccuaccaaggcaaugacguguagcuaugcugagaaguagaauagcc
acaaugggacugagacacggcccauacuccuacgggaggcagcaguaggg
aauuuuucacaaugagcgaaagcuugauggagcaaugccgcgugaacgau
gaaggucuuuaagauuguaaaguucuuuuauuugggaagaaugacuuuag
cagguaauggcuagaguuugacuguaccauuuugaauaagugacgacuaa
cuaugugccagcagucgcgguaauacauaggucgcaagcguuauccggau
uuauugggcguaaagcaagcgcaggcggauugaaaagucugguguuaaag
gcagcugcuuaacaguuguaugcauuggaaacuauuaaucuagagugugg
uagggaguuuuggaauuucauguggagcggugaaaugcguagauauauga
aggaacaccaguggcgaaggcgaaaacuuaggccauuacugacgcuuagg
cuugaaaguguggggagcaaauaggauuagauacccuaguaguccacacc
guaaacgauagauacuagcugucggggcgauccccucgguagugaaguua
acacauuaaguaucucgccuggguaguacauucgcaagaaugaaacucaa
acggaauugacggggacccgcacaagugguggagcauguugcuuaauucg
acgguacacgaaaaaccuuaccuagacuugacauccuuggcaaaguuaug
gaaacauaaugccgagugacagguggugcaugguugucgucagcucgugu
cgugagauguuggguuaagucccgcaacgagcgcaacccuuaucguuagu
uacauugucuagcgagacugcuaaugcaaauuggaggaaggaagggauga
cgucaaaucaucaugccccuuaugucuagggcugcaaacgugcuacaaug
gccaauacaaacagucgccagcuuguaaaagugagcaaaucuguaaaguu
ggucucaguucggauugagggcugcaauucguccucaugaagucggaauc
acuaguaaucgcgaaucagcuaugucgcggugaauacguucucgggucuu
guacacaccgcccgucaaacuaugaaagcugguaauauuuaaaaacgugu
ugcuaaccauuaggaagcgcaugucaaggauagcaccggugauuggaguu
aagucguaacaagguaccccuacgagaacguggggguggauca

.....<<<<..[.(((..>>>>..<<<.<<<<<...<<<<<<........
........<<..<<.<<<<<<....>>>>>>.>>>>.......<<.....
...<.<.<<<..<<........<<.<.<<.....<<<<<<....>>>>>>
......>>.>.....<<<<.............>.>>>....<<<<<<...
.>>>>>>.>>.......>>>>>.>.>.<<.....<<<..<<<<<<<<...
....>>>>>>>>>>>.......>>..<<<<<<<<....>>>...>>>>>.
>>.<<<<<............>>>>>.<<<<....>>>>............
......<<<....<<<<....>>>>..>>>...>.>>>>>...<<<<...
....<<<.....>>>......>>>>...<..<.<<........<<<<<<<
..........>>>>>>>.........>>>....>.....<<<<<(((...
<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>.....
......<<<(......<<<<...<<<.<<<<<<..<<<<<.<<<<.....
<<<<<<<.....>>>>>>>..>>>>.>>>..>>.>>>>>>...<<<.<<<
<...<<<<<<<....<<<<<<<<<..<<........>>.....>>>>>>>
>>...........<<....>>.>>>>>>>..>>>>..>>>...>>>...>
>>>....<<<<<<<.......<<<<.........>>>>....>>>>>>>.
.........<<<<<<..<<<<<<<<<<......>>>>>>>>>>...<<..
.)>>.....>>>>>>.>>>.<<<.......<<<....>>>.....>>>..
..))).]<<.<<.<<<<<<<.....<<<....<<<<<<<<<<......<<
........>>..........<<<<<<.........<<<<<....<<<.<<
....>>.>>>.>>>>>....<<<.<<<..<<<<<<.......<<<<<<<<
<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<.
........>>>>>>>.....<<<<<....>>>>>........>>>>....
.....>>...>>>>>>>>>>....>>>>>>...>>.>>>>>>>>.....<
<<<<<......<<<..<<..<<<<....>>>>..>>....>>>.....>>
>>>>......<....<<<<<<<........>>>>>>>....>.......>
>>.....<<<<<<<..........>>>>>>>...........>>>>>>>>
>..>>....<..<<.<.<<<<.<....<<<<<<..<<<<.....<<<<<<
.<<<..<<....>>.>>>>>>>>>...>.>>>..>>>>>>....>.>>>>
..>.>>...>.....<<<<<<<<<....>>>>>>>>>......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7pir Visualizing translation dynamics at atomic detail inside a bacterial cell.
• Resolution: 12.1 Å
• Binding residue (original residue number in PDB): L28 H32 H35 R37 K38 G39 M40 R43 K45 R46 A49 Q50 K51 R54 K55
• Binding residue (residue number reindexed from 1): L24 H28 H31 R33 K34 G35 M36 R39 K41 R42 A45 Q46 K47 R50 K51

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7pir, PDBe:7pir, PDBj:7pir
• PDBsum: 7pir
• PubMed: 36171285
• UniProt: P57079|RS21_MYCPN Small ribosomal subunit protein bS21 (Gene Name=rpsU)