Structure of PDB 7oyd Chain T Binding Site BS01

Receptor Information
>7oyd Chain T (length=158) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKG
MPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKS
RDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELL
EPIPYEFM
Ligand information
>7oyd Chain 5 (length=3358) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggaaau
guggcguacggaagacccacccggcgccggggggcccaaguccuucugau
cgaggccgcccguggacggugugaggccgguagcggcccccggcgcgccg
ggcccgggucuucccggagucggguugcuugggaaugcagcccaaagcgg
gugguaaacuccaucuaaggcuaaauaccggcacgagaccgauagucaac
aaguaccguaagggaaaguugaaaagaacuuugaagagagaguucaagag
ggcgugaaaccguuaagagguaaacgggugggguccgcgcaguccgcccg
gaggaucaacccggcggcggccggccgugccggggggcggaucuggaccg
ccccccggccggcgaccggccgccgccgggcgcauuuccaccgggcggug
cgccgcgaccggcuccgggacggcugggaaggcccggcggggaagguggc
ccggccggguguuacagcccgcccccggcagcagcgacucgccgaauccc
ggggccgagggagcgagacccgugccgccgcgcucuccccccuggggggg
ccgggccaccccucccacggcgcgaccgcggggcggacuguccagugcgc
cccgggcgggucgcgccgucgggcccggggggccacgcgcgagcgcacgg
ggucggcggcgaugucggcuacccacccgacccgucuugaaacacggacc
aaggagucuaacacgugcgcgagucgggggcuacgaaagccgccguggcg
caaugaaggugaaggccgggccgaggugggaucccgaggccucuccaguc
cgccgagggcgcaccaccggcccgucucgcccgccgcgccggggaggugg
agcacgagcgcacguguuaggacccgaaagauggugaacuaugccugggc
agggcgaagccagaggaaacucugguggagguccguagcgguccugacgu
gcgaaucggucguccgaccuggguauaggggcgaaagacuaaucgaacca
ucuaguagcugguucccuccaaaguuucccucaggauagcuggcgcucuc
gcaguuuuauccgguaaagcgaaugauuagagguaccuauucucaaacuu
uaaauggguaagaagcccggcucgcugguguggagccgggcguggaaugc
gagugccuagugggccacuuuugguaagcagaacuggcgcugcgggauga
accgaacgccggguuaaggcgcccgaugccgacgcucaucagaccccaga
aaagguguugguugauauagacagcaggaugguggccauggaagucggaa
uccgcuaaggaguguguaacaacucaccugccgaaucaacuagcccugaa
aauggauggcgcuggagcgucgggcccauacccggccgucgcuggcaguc
ggcagagcgagaaagagagugggcggacgcuacgccgcgacgaguaggag
ggccgcugcggugagccuugaagccuagggcgcgggcccggguggagccg
ccgcaggugcagaucuuggugguaguagcaaauauucaaacgagaacuuu
gaaggccgaaguggagaaggguuccaugugaacagcaguugaacaugggu
cagucgguccugagagaugggcgagcgccguuccgaagggacgcucagcc
gaucgaaagggagucggguucagauccccgaauccggagcggagaugggc
guccagugcgguaacgcgaccgaucccggagaagccggcgggagccccgg
ggagaguucucuuuucuuugugaagggcagggcgcccuggaauggguucg
ccccgagagaggggcccgugccuuggaaagcgucgcggcguccggugagc
ucucgcuggcccuugaaaauccgggggagaggguguaaaucucgcgccgg
gccguacccauauccgcagcaggucuccaaggugaacagccucuggcaug
uuggaacaauguagguaagggaagucggcaagccggauccguaacuucgg
gauaaggauuggcucuaagggccgacuuagaacuggugcggaccagggga
auccgacuguuuaauuaaaacaaagcaucgcgaaggcccgcggcgggugu
ugacgcgaugugauuucugcccagugcucugagucaaagugaagaaauuc
aaugaagcgcggguaaacggcgggaguaaugacucucuuaagguagccaa
augccucgucaucuaauuagugacgcgcaugaauggaugaacgagauucc
cacugucccuaccuacuauccagcgaaaccacagccaagggaacgggcuu
ggcggaaucagcggggaaagaagacccuguugagcuugacucuagucugg
cacggugaauucacugacccggugaggcgggggggccucgcuucuggcgc
caagcgcccgcgggcgcgacccgcuccggggacagugccagguggggagu
uugacuggggcgguacaccugucaaacgguaacgcagguguccuaaggcg
agcucagggaggacagaaaccucccguggagcagaagggcaaaagcucgc
uugaucuugauuuucaguacgaauacagaccgugaaagcggggccucacg
auccuucugaccuuuuggguuuuaagcaggaggugucagaaaaguuacca
cagggauaacuggcuuguggcggccaagcguucauagcgacgucgcuuuu
ugauccuucgaugucggcucuuccuaucauugugaagcagaauucaccaa
gcguuggauuguucacccacuaauagggaacgugagcuggguuuagaccg
ucgugagacagguuaguuuuacccuacugaugauguguuguugccauggu
aauccugcucaguacgagaggaaccgcagguucagacauuugguguaugu
gcuuggcugaggagccaauggggcgaagcuaccaucugugggauuaugac
ugaacgccucuaagucagaaucccgcccaggcggaacgauagcgccggag
ccucgguuggccucggauagccggccggugcggagagcccuucgucccgg
gaaacgggccggaaaggggccgcgcccgucacgcaccgcacguucguggg
gaaccuggcgcuaaaccauucguagacgaccugcuucugggucgggguuu
cguacguagcagagcagcugcgaucuauugaaagucagcccucgacacaa
ggguuugu
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.>>>>...((......<<<.....))>>>...>.>>>>>>>...>.>>>>
>>...>>>>>>>>>.......<<<<<<<........>>>>>>>.....((
(((..<<<<<<)))))..]]].............................
.....<<....>>...............<<<<....>>>>..........
........................<<<<<<<<..<<<.<<...<<<<<<<
<.<<<....<<<<<<<<<<<<<<<<<<.<<<<<<<<<<<<.<<..>>>>>
>>>>>>>>>>>>>...>>>>>>>>>>>>>>......>>>.>>>>>>>>..
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<<<..>>>>>.......>>>..>>..>>>.........>>>>>>...>>>
>>>>>>>.....<<.......>>......<<<<<<.<<<<<<..>>>>>>
...<.<<..<<<.<<<<<<<<<<<<<<.<<<<<<<.<<<<..>>>>.>>>
>>>..>..>>>>>>>>>>>.>>>...>>>>>.>.......>>>>>>....
.>>>.>>>>>...>>>>>...>>>>>>>>..<<<<........>>>><<<
<<<....<<<<<<<<<<<<<..<<<...<<<<.....>>>>.....>>>.
..<<....>>...<<<<.>>>>..<<<<<...<<<..<<.....(((.[[
..>>..>>>....>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>>>
.>>....>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<.
.<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<...
.....>>>>.>>>....>>>>>>>>>...<<.......>>......>>>>
>>...>..>.>>..<<<<<<....<.<<<....>>>.><<.<<<<<<<..
<<<.<<<<<<<<<...<<<....<<<..<.<<<..>>>.>..>>>..>.>
>...>>>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>>>>
>>>>>>>..>>..<<<<.<<<<<.....>>>>>.>>>>....<<<.....
.>>>...<<<<<<<...<<<(((.......<<<<<......<........
..<<<.<<<<<<<<<<.......<<<<<.<<....<<.........>>..
..>>.........<<......>>...>>>>>...>>>>>>>>>>>>>...
.......))).>....>>>>>..>>>...>>>>>>><<<<<<.<<<....
................]].)))...........>>>>>>>>>....>>>>
>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...>>>>
>>>>>>........>>>>>><<.....<<.....<<<<<<.......>>>
>>>.<<<.....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>..
..((<<<<<<...<<....<<<....>>>..........<<...>>....
..>>....>>>..<<<<<........>>>>>))<<<<.<<<<<..<<<<.
.>>>>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<<<.<<<<
<<<<<<..{{{..>>>>>>....<<<<<.<<<<.<<<<.....<<<....
.>>>.....>>>>>>>>..>>>>>.....<<<<<..>>>>>>>>>...>>
>>>>>>>>>>.........>>>>>>>..>..........>>.>>>.>>>>
.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>...
.<<<<.....<<<<<<<.<<.........<.....<<<<<..........
.....>>>>><<.<<<<<<......>>>>>>.>>............<<<<
<<<<<..<<<.........>>>..<<<<<<<....<<<<.....>>>>..
....>>>>>>>...<<..<<<..<<<<<<...<<.....<<<<....>>>
>.....>>..>>>>..>>>>><<<<<<....>>>>>>........<....
.......<<<<<.......>>>>>.....>.....>>....>>.>>>>>>
>..>..>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>
>>....[[[[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<
<<<.<<<<..>>>>...<<<<<.....<<<<..<<..>>...........
...<<<<<<..>>>>>>..>>>>..>>>>>....>>>>>>>>>..>>>>>
...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<
<<<...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>
>...<<<..<<<<.......>>>>..>>>.<<<....>>>.>>)))]...
...((((((..(((..>>>>>>.)))))))))..........]]]]..}}
]]]].......<<.<.<.<<<<<<...<<.......>>...>>>>>>...
>>.>.>.......<<<<<.<<<<<<..<.<.<<<<<......>>>>>...
>.>.<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<
<<....>>>.>>>>....}}..}}}.]]]]].....<<<<<<.<..<<<.
.<.<<<<<.................>>>>>.><<<<....<<<<....<<
.<<<<<<.}}}..>>>>..>>.>>...>>>>...>>>><<<<....<<<<
<...........>>>>>....>>>>.>>>...>.>>>>>>.<<<<<<<..
<<<<....<<<........<<<<..>>>>.......>>>...<<<..<<<
<......<<<.......>>>....>>>>..>>>..............>>>
>..>.>>>>>>.<<<<<.<.............>....<<.<<<<<<<.<<
.....<<<<....<<<..>>>...>>>>....>>....>>>>.>>>.>>.
.>>>>>..
Receptor-Ligand Complex Structure
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PDB7oyd A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
T2 N3 T4 K5 G6 K7 R8 R9 G10 R12 Y13 M14 S16 R17 F19 H22 G23 D41 K43 G46 T47 Q49 K50 G51 H54 Y57 H58 G59 K60 T61 T68 Q69 H70 N77 K78 V80 K81 L85 K87 R88 I89 R92 K100 S101 R102 S104 F105 R108 V109 K110 D113 W125 V126 L128 K129 R130 P132 F140 R142
Binding residue
(residue number reindexed from 1)
T1 N2 T3 K4 G5 K6 R7 R8 G9 R11 Y12 M13 S15 R16 F18 H21 G22 D40 K42 G45 T46 Q48 K49 G50 H53 Y56 H57 G58 K59 T60 T67 Q68 H69 N76 K77 V79 K80 L84 K86 R87 I88 R91 K99 S100 R101 S103 F104 R107 V108 K109 D112 W124 V125 L127 K128 R129 P131 F139 R141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7oyd, PDBe:7oyd, PDBj:7oyd
PDBsum7oyd
PubMed36653451
UniProtG1SHQ2|RL21_RABIT Large ribosomal subunit protein eL21 (Gene Name=RPL21)

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