Structure of PDB 7oid Chain T Binding Site BS01

Receptor Information
>7oid Chain T (length=159) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRG
MSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAEST
SGRGQCLKRIRGIMEKVYCHYFVKLVEGPPPPPEPPKTAVAHAKEYIQQL
RSRTIVHTL
Ligand information
>7oid Chain A (length=1472) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagcaaccuuagcc
aaaccauuuacaaauaaaguauaggcgauagaaauugauggcgcaauaga
uauaguaccgcaagggaaagaugaaaaauuauaaccaagcauaauauagc
aaggacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuu
ugcaaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaag
aacagcuaagagcacacccgucuauguagcaaaauagugggaagauuuau
agguagaggcgacaaaccuaccgagccuggugauagcugguuguccaaga
uagaaucuuaguucaacuuuaaauuugcccacagaaccaaauccccuugu
aaauuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaa
aaccuuguagagagaguaaaaaauuuaacacccauaguaggccuaaaagc
agccaccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacau
auaacugaacuccucacacccaauuggaccaaucuaucacccuauagaag
aacuaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccu
gcgucagauacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
acacauguuuaacggccgcgguuaaccgugcaaagguagcauaaucacuu
guuccuuaaauagggaccuguaugaauggcuccacgaggguucagcuguc
ucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggcauaa
cacagcaagacgagaagacccuauggagcuuuaauuuauuaaugcaaaca
guaaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccucaauu
gauccaauaacuugaccaacggaacaaguuacccuagggauaacagcgca
auccuauucuagaguccauaucaacaauaggguuuacgaccucgauguug
gaucaggacaucccgauggugcagccgcuauuaaagguucguuuguucaa
cgauuaaaguccuacgugaucugaguucagaccggaguaauccaggucgg
uuucuaucuacuuuauuccucccuguacgaaaggacaagagaaauaaggc
cuacuucacaaagcgccuucccccguaaaugauaucaucucaacuuagau
acccacacccaagaacaggguu
<<<.......<<<<....................................
<......>.......<.....<<.....>>....>....>>.>>......
.......<<....>>......................>>>..........
.<<<.......>>>...<.<........>.>.<<<<<<.........<<<
.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<
<<..<<<...>>>...<<<<.<<<<........>>>>>>>>....>>>.>
>>>>...<<.......>>......>.>>>>......>.>>..<<<<<<..
..<<<<....>>>><<<.<<<<<<<<<<.....<<......>>.....>>
>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>...<<<....
..>>>....<<<.<<<...<..............<....<<<........
.>>>....>.......<<<......>>>......................
.....>...>>>>>>........>>>>>>...<<<<<......>>>>>..
.......>>>>>>.......<<..<<<....>>><<<<..<<<<......
..<<<<<...>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>.....>>>>..<
<<<...<<<<<<<<.<<.........<......<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.<<<..<<<
<<....>>>..>>>>><<<<<....>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>....>>.>>>>.....>..>
>.>>>>>>>>>>>>.>>...........<<<<<........>>>>>....
...<<..<<<.<<......<<<<.<<<<<<..<<<<..<<<<<<<<....
......>>>>>>>>.>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
....<<<....>>>............>>>>..>>>>>>.......<<<..
<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.......<<<
<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>
>>>.....>>>>>..>...>>>>.>....<<<<<<<....>>>.>>>>..
..>>..>>>.>>..<<<.<<<.................>>>.>>><<<<<
...<<<....>>>.>>>>>......<<<................>>>...
......<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB7oid A distinct assembly pathway of the human 39S late pre-mitoribosome.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		I47 S48 K50 W51 K54 K81 Y82 S83 K84 D85 K86 W88 R95 D110 K111 K112 R149 G150 R157 M167 K169 V170 H173 F175 S205 R206 T207 H210
Binding residue
(residue number reindexed from 1)		I1 S2 K4 W5 K8 K35 Y36 S37 K38 D39 K40 W42 R49 D64 K65 K66 R103 G104 R111 M114 K116 V117 H120 F122 S152 R153 T154 H157
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oid, PDBe:7oid, PDBj:7oid
PDBsum7oid
PubMed34315873
UniProtQ9NWU5|RM22_HUMAN Large ribosomal subunit protein uL22m (Gene Name=MRPL22)

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