Structure of PDB 7cow Chain T Binding Site BS01

Receptor Information
>7cow Chain T (length=75) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSI
KRLVTTGVLKQTKGVGASGSFRLAK
Ligand information
>7cow Chain I (length=353) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgctgcgaaaaaaaaaacgcatcccggtgccgaggccgctcaattggtcg
tagacagctctagcaccgcttaaacgcacgtacgcgctgtctaccgcgtt
ttaaccgccactagaagcgcttactagtctccaggcacgtgtgagaccgg
cacatgaaaaaaaaaatgcatgctcgagtatgaaaaaaaaaatcgcatcc
cggtgccgaggccgctcaattggtcgtagacagctctagcaccgcttaaa
cgcacgtacgcgctgtctaccgcgttttaaccgccactagaagcgcttac
tagtctccaggcacgtgtgagaccggcacatgaaaaaaaaaacgcagcgg
tac
Receptor-Ligand Complex Structure
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PDB7cow Engineering nucleosomes for generating diverse chromatin assemblies.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		R42 R47 N63 K69 V87 A89
Binding residue
(residue number reindexed from 1)		R20 R25 N41 K47 V65 A67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003680 minor groove of adenine-thymine-rich DNA binding
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031490 chromatin DNA binding
GO:0031491 nucleosome binding
GO:0031492 nucleosomal DNA binding
Biological Process
GO:0006334 nucleosome assembly
GO:0030261 chromosome condensation
GO:0031507 heterochromatin formation
GO:0045910 negative regulation of DNA recombination
GO:2000679 positive regulation of transcription regulatory region DNA binding
Cellular Component
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0000791 euchromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005794 Golgi apparatus
GO:0015629 actin cytoskeleton
GO:0016604 nuclear body
GO:0017053 transcription repressor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cow, PDBe:7cow, PDBj:7cow
PDBsum7cow
PubMed33590100
UniProtP07305|H10_HUMAN Histone H1.0 (Gene Name=H1-0)

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