Structure of PDB 6wdr Chain T Binding Site BS01

Receptor Information
>6wdr Chain T (length=143) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAE
GWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSIN
RKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE
Ligand information
>6wdr Chain 2 (length=1647) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguug
gccggucggauuuccaacggggccuuuccuucuggcuaaccuugaguccu
uguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcguauugcucgaauauauuagcauggaauaauagaauaggac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcauaacuacugcgaaagcauuugccaaggacguuuucau
uaaucuaaccauaaacuaugccgacuagggaucgggugguguuuuuuuaa
ugacccacucggcaccuuacgagaaaucaaagucuuuggguucugggggg
aguauggucgcaaggaugaaacuuaaaggaauugacggaagggcaccacc
aggaguggagccugcggcuuaauuugacucaacacggggaaacucaccag
guccagacacaauaaggauugacagauugagagcucuuucuugauuuugu
gggugguggugcauggccguucuuaguugguggagugauuugucugcuua
auugcgauaacgaacgagaccuuaaccuacuaaauaguggugcuagcauu
ugcugguuauccacuucuuagagggacuaucgguuucaagccgauggaag
uuugaggcaauaacaggucugugaugcccuuagacguucugggccgcacg
cgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuug
guaaucuugugaaacuccgucgugcuggggauagagcauuguaauuauug
cucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguugau
uacgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaaug
gcuuagugaggccucaggaucugcuuagagaagggggcaacuccaucuca
gagcggagaauuuggacaaacuuggucauuuagaggaacuaaaaguc
..<<<<<...((((>>>>><<<<.<<<<.....<.<...<.......<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<..<<..<<....<<<..................<.....<<.
<<.......>>.>>......>.........<<<<<..<......>..>>>
>><...<<<<<<......(((.(((.........................
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>..........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<.<.......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.........)).........>>>>.>>>>>....>>>>>
>>>.........<<.<<................<<....<<<<<<.<<<<
<............>>>>>.>>>>>>.....<<<<<.....<..<<<<...
....>>>>..>.....>>>>>....<<<<<.<<.......<<...<....
...>..<<<.....>>>....>>......>>.>>..>>>.........<<
<..<<<<.<<......))).)))..>>.>>>>.>>>.....>>....<<<
<<<.<<...<<<<........<<....>>...>>>>...>>>>>.>>>..
....................((.((.<<<..<<<<<<<<.<<<.<....>
.>>>>>>>>>>>..>>>...((..>>))...)).....))...>>.<<<.
.......<......>......>>>..)))).....<..<<<<<<......
...<<<..<<..............<<........>>..........<<<<
<......<.<<............<............>..........>>.
.>..................<....<<<.<<<<......>>...<<<...
...>>>...>>.>>>....<<<<..<<..<<<<..<<<<<...<<<....
..>>>.....>>>>>..>>>>.>>....<<<<<<.....>>>>>>.....
...>>>>....>.........................>>>>>........
....>>.....<<<<<<<......<<.....<<..<<<<....>>>>..>
>....>>.......>>>>>>>...........<<<<<<..........>>
>>>>..........>>>.......<<<<...............>>>>...
.........>>>>>>.>.................<<<<.....<<<<<<<
<<<.<<<..<.<<..<...<<<<<<<.<<....<<<....>>>....>>.
>>>>>>>...>..>>.>..>>>.>>>>>>>>>>....>>>>......
Receptor-Ligand Complex Structure
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PDB6wdr An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
P2 G3 R7 Q12 V37 S41 N43 E44 P47 Q48 R57 H64 R68 K69 G72 V73 G74 K75 K78 G82 R86 G87 V88 R89 P90 S97 S99 R102 Q106 K119 R122 E126 Q129 R130 D133 R134
Binding residue
(residue number reindexed from 1)
P1 G2 R6 Q11 V36 S40 N42 E43 P46 Q47 R56 H63 R67 K68 G71 V72 G73 K74 K77 G81 R85 G86 V87 R88 P89 S96 S98 R101 Q105 K118 R121 E125 Q128 R129 D132 R133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000054 ribosomal subunit export from nucleus
GO:0006412 translation
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6wdr, PDBe:6wdr, PDBj:6wdr
PDBsum6wdr
PubMed33219089
UniProtP07280|RS19A_YEAST Small ribosomal subunit protein eS19A (Gene Name=RPS19A)

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