Structure of PDB 6w6p Chain T Binding Site BS01

Receptor Information
>6w6p Chain T (length=112) Species: 474186 (Enterococcus faecalis OG1RF) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFTPNKSAGIIE
KVLMSAVANAENNFDLDVESLVVSEAFVNEGPTMKRFRPRAKGSASPINK
RTSHITVVVTEK
Ligand information
>6w6p Chain A (length=2739) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaagugaauaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacuaacaccgauaugcuuuggggagcuguaaguaagcuauga
uccagagauuuccgaaugggggaacccaauaucuuuuauaggauauuacu
uuucagugaauacauagcugauuagagguagacgcagagaacugaaacau
cuuaguaccugcaggaagagaaagaaaauucgauucccugaguagcggcg
agcgaaacgggaagagcccaaaccaacaagcuugcuuguugggguuguag
gacuccgauaugguagucuguuaguauaguugaaggauuuggaaaauucc
gcuaaagagggugaaagccccguagacgaaaugcugacaacaccuaggag
gauccugaguacggcggaacacgagaaauuccgucggaauccgcggggac
caucccgcaaggcuaaauacucccuagugaccgauagugaaccaguaccg
ugagggaaaggugaaaagcaccccggaaggggagugaaauagauccugaa
accgugugccuacaacaagucaaagcucguuaaugagugauggcgugccu
uuuguagaaugaaccggcgaguuacgauugcaugcgagguuaagucgaag
agacggagccgcagcgaaagcgagucugaauagggcgaaugaguauguag
ucguagacccgaaaccaugugaucuacccauguccagguugaaggugcgg
uaaaacgcacuggaggaccgaacccacguacguugaaaagugcggggaug
agguguggguagcggagaaauuccaaacgaacuuggagauagcugguucu
cuccgaaauagcuuuagggcuagccucggaauugagaaugauggagguag
agcacuguuuggacuaguucagauaaacuccgaaugccauucauuuauau
ccgggagucagacugcgagugauaagauccguagucgaaagggaaacagc
ccagaccaccagcuaaggucccaaaauauauguuaaguggaaaaggaugu
gggguugcacagacaacuaucgagugacccugcgccgaaaauguaccggg
gcuaaacauauuaccgaagcuguggacuacaccauuagguguagugguag
gagagcguucuaagggcguugaaggucgaucgugaggacggcuggagcgc
uuagaagugagaaugccgguaugaguagcgaaagacaggugagaauccug
uccaccguaugacuaagguuuccuggggaaggcucguccgcccaggguua
gucgggaccuaagccgaggccgauaggcguaggcgauggacaacagguug
auauuccuguaccaguuguuuguuugagcaauggagggacgcaguaggcu
aaggaaugcaugcgauuggaagugcauguccaagcaaugagucuugagua
gaguuaaaugcuuuacucuuuaaggacaaguugugacggggagcgaaaua
guagcgaaguuccugacgucacacugccaagaaaagcuucuagugagaaa
acaacugcccguaccguaaaccgacacagguagucgaggagaguauccua
aggugagcgagcgaacucucguuaaggaacucggcaaaaugaccccguaa
cuucgggagaaggggugcugacuucggucagccgcagugaauaggcccaa
gcgacuguuuaucaaaaacacaggucucugcaaaaucguaagaugaagua
uaggggcugacgccugcccggugcuggaagguuaagaggauggguuagcu
ucggcgaagcucagaauugaagccccaguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgacccgcacga
aaggcguaacgauuugggcacugucucaacgagagacucggugaaauuuu
aguaccugugaagaugcagguuacccgcgacaggacggaaagaccccaug
gagcuuuacuguaguuugauauugaguguuuaacccucuaacccgcacca
cuaaucguggugggagacagugucagaugggcaguuugacuggggcgguc
gccuccuaaaagguaacggaggcgcccaaagguucccucagaaugguugg
aaaucauucgaagaguguaaaggcagaagggagcuugacugcgagaccua
caagucgagcagggacgaaagucgggcuuagugauccggugguuccgcau
ggaagggccaucgcucaacggauaaaagcuacccuggggauaacaggcuu
aucucccccaagaguccacaucgacggggagguuuggcaccucgaugucg
gcucgucgcauccuggggcuguagucggucccaaggguugggcuguucgc
ccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucgg
ucccuauccgucgcgggcguuggaaauuugagaggagcuguccuuaguac
gagaggaccgggauggacuuaccgcugguguaccaguuguucugccaagg
gcauugcuggguagcuauguagggaagggauaaacgcugaaagcaucuaa
gugugaagcccaccucaagaugagauuucccauuucuuuaagaaaguaag
accccugagagaugaucagguagauagguuggaaguggaaggcuagugau
aguuggagcggaccaauacuaaucggucgaggacuuaac
<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
..<<<<<.........>>>>>..>>.>>....<<<<<......<<....>
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<...<.<<<.<<.<<<<<<<<<.<<<...<<<.<......>.>>>
((......<<<.....))>>>...>>>...>>>>>>>>>>>>>>>.>>>>
..>>>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<
<<<>>>>>..)))......]].>>>>>>>.]]...............<<.
...>>....]].........<<<<....>>>>..................
>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<
........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<<....
.>>>...>>>...<<....>>..<<<<.....>>>>......>>>>>>>>
>>>>>..<<.<..<<<<.<<.....<<<<<<<<<..<<<....<<<<<<.
.....>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>...
.>>>>>>>>>...<<<.....>>>......>>.>>>...>..>.>>..<<
<<<<....<<<<<....>>>>><<<<<<<<..<..<<<<<<<<<.....<
<<...<<<<<<<<....>>>>>>>>..>>.>.....>>>>.>>>>>..>>
>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>
>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<
<<<<<<<........<...>....>>>>>>>>>.>>...........)))
.....>>>>>>.>>>...>>>>>>><<<<<<<......>>>>>>>....>
>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>
>>>>>>..>.....>>>>>><......<<....<<<<<<.......>>>>
>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....
((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<...
.....>>>>>))<<<<<<<.........<...<<<<....<<<<..<<<.
.<<<<<...........{...........<<..<<<<<..<<<<.<<<<<
<<<<.....>>>>>>>>>.....>>>>..>>>>>...>>...<<......
...>>....>>>>>...>>>...>>>>.........>>>>..>.......
>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>.
.>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<....
<<..>>.....>>>>><<<<<<....>>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<<....>>>......
.>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<<<<..<<.
...>>...>>>>>...>>..>>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<<.....>>>>>>.....>..
..>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<<<<<<<.<<<.<<<.>>>.>>>....<<.<<<<<
<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>>>
<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<....
...>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<...
...>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>
>>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.
<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<
<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>
>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>..
..]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<......
.........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.}..>>>
>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<...........>
>>>>...>>>>.>>>>.......>>>>>>>..<<<......>>>.....<
<<<<<<<<.......>>>>>....<<<<<<<<..<<.....<<<<....>
>>>....>>...>>>>>.>>>...>>>>....>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6w6p Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T11 K13 R16 R20 K21 N46 K47 K54 A61 N62 N65 N66 N82 E83 R89 R91 P92 R93 A94 K95 G96 S97 S99 P100 I101 N102 H107
Binding residue
(residue number reindexed from 1)		T8 K10 R13 R17 K18 N43 K44 K51 A58 N59 N62 N63 N79 E80 R86 R88 P89 R90 A91 K92 G93 S94 S96 P97 I98 N99 H104
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6w6p, PDBe:6w6p, PDBj:6w6p
PDBsum6w6p
PubMed33004869
UniProtA0A1B4XKT6

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