Structure of PDB 6gc7 Chain T Binding Site BS01

Receptor Information
>6gc7 Chain T (length=93) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKL
FEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNL
Ligand information
>6gc7 Chain A (length=1901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccgguggugaaaggccaaucaa
accgggagauagcugguucuccccgaaagcuauuuagguagcgccucgug
aauucaucuccggggguagagcaccaaacugcgaauaccggagaauguua
ucacgggagacacacggcgggugcuaacguccgucgugaagagggaaaca
acccagaccgccagcuaaggucccaaagucaugguuaagugggaaacgcg
gaagauguaacggggcuaaaccaugcaccgaagcugcggcagcgacgcuu
augcguuguuggguaggggagcguucuguaagccugcgaaggugugcugu
gaggcaugcuggagguaucagaagugcgaaugcugacauaaguaacgaua
aagcgggugaaaagcccgcucgccggaagaccaaggguuccuguccaacg
uuaaucggggcagggugagucgaccccuaaggcgaggccgaaaggcguag
ucgaugggaaacagguuaauauuccuguacuugguguuacugcgaagggg
ggacggagaaggcuauguuggccgggcgacgguugucccgguuuaagcgu
guaggcugguuuuccaggcaaauccggaaaaucaaggcugaggcgugaug
acgaggcacuacggugcugaagcaacaaaugcccugcuuccaggaaaagc
cucuaagcaucagguaacaucaaaucguaccccaaaccgacacagguggu
cagguagagaauaccaaggcgcuugagagaacucgggugaaggaacuagg
caaaauggugccggcacgcugauauguaggugaggucccucgcggaugga
gcugaaaucagucgaagauaccagcuggcgccaggcugucuccacccgag
acucagugaaauugaacucgcugugaagaugcaguguacccgcggcaaga
cggaaaucccuaucugccgugggcgcuggagaacugaggggggcugcucc
uaguacgagaggaccggaguggacgcaucacugguguucggguugucaug
ccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaagc
aucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaagg
guccugaaggaacguugaagacgacgacguugauaggccggguguguaag
cgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaacc
u
<<<<<<<<......<<<<<<<<<<<....<.<<.<<<<<<<<<<<<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<......>..<<<<<<.....<<....
.>>....>>>>>>..<<<..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>.>..>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<......>>>>>..>>>......>>.>>>>>>>.>>.....
..........<<....>>....>>.........<<<.......>>>....
.........>....>>>>>>>>>>>.......<<<<..<<<<<......>
>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.<<.....>>.......
>>>>>>......>.>>..<<<<<<....<<<<<....>>>>>..<<<<<<
<...<<<<<<<<<......<<.......>>.......>>>>>>.>>>...
>>>>>>>.....<<<<<<<<<<......>>>>>>>>>>....<<<.....
.>>>...<<<<.<<<...<<<(((.....<<<<<<...........<..>
...........))).....>>>>>>.>>>...>>>>>>><<<.<..<...
...>..>.>>>....>>>>>><<<<<<<...<<<......<<<<<<<<..
..>>>>>>>>...>>>..>>>>>.>>.....>>>>>><......<<....
.<<<<<<.......>>>>>><<<<....<<.<<.<<...<<<<<<...<<
.....>>.>>>>>>....((<<<.<<<...<<....<<<....>>>....
>>...>>>...<<<<........>>>>.))<<<<<<<<<<<<<...<<<<
....<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<<
...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>>>...>
><..<<<<<....>>>>>...>>>>>>...>>>...>>>>.........>
>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>>.>
>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<........
.......<<<<..>>>><<<<<......<<<...<<<<.....>>>>...
>>>....>>>>>............<<<<..>>>>.....>>.>>>>>>>>
.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<
.<.......>..>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<
...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<)
)).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<......
.....>>>>>....>>>.>>>>.......>>>>>>>..<<<<<.....>>
>>>.....<<..<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>.....>>.....>>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gc7 Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		M1 I2 R3 K9 H15 E18 K40 N59 T60 L61 V62 K64 K66 K68 H70 Q72 R73 R76 R77 S78 K81 K82 Y84
Binding residue
(residue number reindexed from 1)		M1 I2 R3 K9 H15 E18 K40 N59 T60 L61 V62 K64 K66 K68 H70 Q72 R73 R76 R77 S78 K81 K82 Y84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gc7, PDBe:6gc7, PDBj:6gc7
PDBsum6gc7
PubMed29883607
UniProtP0ADZ0|RL23_ECOLI Large ribosomal subunit protein uL23 (Gene Name=rplW)

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