Structure of PDB 6az1 Chain T Binding Site BS01 |
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| >6az1 Chain 1 (length=1760)
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gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaca
ucagacguaaucugccgcaaaaaucuugcgguccgcaaaauuggauaacu
uggcgaaacgccaagcuaauacaugaaccaaccgggugucuccagagacg
cccagcgaaugaaugacaaaaccaaugccugcaguaacacccagcagugu
ugacucaauucauuccgugcgaaagccggcccggcgucuuuugacgaaca
acugcccuaucagcuggugauggccguguaguggacugccauggcguuga
cgggagcgggggauuaggguucgauuccggagagggagccugagaaauag
cuaccacuucuacggagggcagcaggcgcgcaaauugcccaaugucaaaa
caaaacgaugaggcagcgaaaagaaauagaguuuucaaugggggauauuu
aaacccauccaauaucgaguaacaauuggaggacaagucuggugccagca
cccgcgguaauuccagcuccaaaagcguauauuaaugcuguugcuguuaa
aggguucguaguugaacugugggcuguucccguccauucggaugacccug
cagcccgugaacagaaacaacgggagugggggcguccgugauuuuuuacu
gugacuaaagaagcgugacuaaagcagucaugacugaauuagaaagcaug
ggauaacaaaggagcaguuuuaaaggucuauuggagauuauggagcugug
cgacaagugcuuucccauaggaaugaaggaggguagucgggggagaacgu
acuggggcgucagaggugaaauucuuagaccgcaccaagacgaacuacag
cgaaggcauucuucaaggauaccuuccucaaucaagaaccaaagugugga
gaucgaagaugauuagagaccauuguaguccacacugcaaacgaugacac
ccaugaauuggggauccuuacguaucuuucucagcacguuuucuguuuuc
acgcgaaagcuuugagguuacagucucaggggggaguacguucgcaagag
ugaaacuuaaagaaauugacggaauggcaccacaagacguggagcgugcg
guuuaauuugacucaacacggggaacuuuaccagauccggacaggaugag
gauugacagauugaguguucuuucucgauucccugaaugguggugcaugg
ccgcuuuuggucgguggagugauuuguuugguugauuccgucaacggacg
agauccaagcugcccaguagaauucagaauugcccauaggauaggcauuc
gucgaauucuucucugcgggauuccuuguaaugcacaaggugaaauuuug
ggcaacagcaggucugugaugcuccucaauguucugggcgacacgcgcac
uacaaugucagugagaacaagaaaaacgagucgaaccuacuugaucaaaa
gaguggggaaaccccggaaucacauagacucacuugggaccgaggauugc
aauuauuggucgcgcaacgaggaaugucucguaggcgcagcucaucaaac
ugugccgauuacgucccugccauuuguacacaccgcccgucguuguuucc
gaugauggugcaauacaggugaucggacgaaaguucaccgauauuucuuc
aauagaggaagcaaaagucguaacaagguagcuguaggugaaccugcagc
uggaucauuu |
...<<<<<.{.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<..<....
.<<<..<<..<<...<<.<<.....<<<<<<.>>>>>>...<<.....<<
<<<<.....>>>>>>......>>..........<<<<<<<<<..>>>>>>
>>>.<<<<<<<<<<.....((.{....<..>...................
.......>>>>>>>>...>>....<<<<<.>>>>>...>>.>>..>>>>.
.>>>.<<<....<<<....<<<<<.<<.......>>.>>>>>>>>.....
.>>>..<<<<<<<<....>>>>...>>>>>>>.<<.<<<..........>
>>.>>.<<<<....>>>>...>>>>>>.........<<<....<<<....
......>>>..>>>..>....>>>....<<<..>>>.....<<<<.....
.......>>>.....>.........<<<<<((....<.<<<<.....<<.
.))>>.......>>>>>>>>>>..>>>>>>>>>>.........<<<[[..
...<<<<...<<<..<....<...<<.<<....<......>..>>...>>
...>.........................................<<<<<
<<<.......<<...<.......>..<<<..>>>....>>......>>>>
>..>>>..........<<<.<..<<...<......}.))...>..>>..>
.>>>...................>......<<<<<.<<...<<<<<<<<.
.<<<<.<<<...<<<......>>>......>>>.>>>.>.>>.......<
<....>>.>>>>>>...>>>>>.>>....>>>...>>>>...<<<<<<<<
...<...<<<<.<.....>.>>>>...>>>>>>>>>.........<<<.<
<...<..<.<<<<<..........<.<......>.>..>>>>>.>..>..
..<<..]]>>.....>>.....>>>.>>>.<<<......<<<<....>>>
>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<.<<<<<
<<......<<........>>..........<<<<<......<<<<.....
....<<.<<<........>>>.>>.......>>>>...<<.<<<..<<.<
<<<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>.
...<<<<<.<<<<.....<<<<<<<.<<<<................>>>>
...>>>>>>>.....>>>>....<<<<<<.....>>>>>>.......>>>
>>....>>>.>>>.....>>>>>>>.......>>>>>...>>.>>>>>.>
>.....<<<.<<<.......<.....<<<.>>>..<<<<<<<........
>>>>>>>....>........>>>...>>>......<....<<<..<....
......>..>>>.....>.....>>>>>>....<<<<<<<.........>
>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<<<<<
..<<.<<<.<.<<<<..<<<<<.<........>.>>>>>..>>>>.>.>>
>.>>..>>>>>>>>..>.>>...>.....<<<<<<<<<<..>>>>>>>>>
>......... |
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| PDB | 6az1 Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin. |
| Resolution | 2.7 Å |
Binding residue
(original residue number in PDB) | V2 R3 M4 H5 N7 G8 R9 G10 K11 A12 S13 S14 A15 L16 P17 R20 S30 R31 P47 S48 G51 M52 R55 A61 Q62 G68 R69 K70 I71 L72 R73 K76 H77 D87 F90 L91 R94 Q97 M98 H101 H105 T107 D108 R109 D110 Y113 R114 S120 R121 R124 Y128 V132 K133 Q134 |
Binding residue
(residue number reindexed from 1) | V1 R2 M3 H4 N6 G7 R8 G9 K10 A11 S12 S13 A14 L15 P16 R19 S29 R30 P46 S47 G50 M51 R54 A60 Q61 G67 R68 K69 I70 L71 R72 K75 H76 D86 F89 L90 R93 Q96 M97 H100 H104 T106 D107 R108 D109 Y112 R113 S119 R120 R123 Y127 V131 K132 Q133 |
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| Enzyme Commision number |
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