Structure of PDB 5nrl Chain T Binding Site BS01

Receptor Information
>5nrl Chain T (length=462) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFPDTKLPR
SSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINFER
KLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDRARDL
DLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLDDE
KYLLTPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDF
EHSYCRGSLRSEAKGIYCPFCSRWFKTSSVFESHLVGKIHKKNESKRRNF
VYSEYKLHRYLKYLNDEFSRTRSFVERKLAFTANERMAEMDILTQKYEAP
AYDSTEKEGAEQVDMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFN
EERHIYHLRCLGIEPSSVFKGITKIKEAQELWKNMQELELEEEDEEGNVM
SKKVYDELKKQG
Ligand information
>5nrl Chain 2 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugaaguguaguaucuguucuuuucaguguaacaacugaaau
gaccuaggcucauacacauuuuuuggcaggacgggaagaggagacgucgc
gacccucgcacgagucguucuugacuuggucgcuugauguuucuucuucc
cguuc
Receptor-Ligand Complex Structure
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PDB5nrl Structure of a pre-catalytic spliceosome.
Resolution7.2 Å
Binding residue
(original residue number in PDB)		Y409 W410 R419 R434
Binding residue
(residue number reindexed from 1)		Y367 W368 R377 R392
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nrl, PDBe:5nrl, PDBj:5nrl
PDBsum5nrl
PubMed28530653
UniProtP19736|PRP9_YEAST Pre-mRNA-splicing factor PRP9 (Gene Name=PRP9)

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