Structure of PDB 4v9f Chain T Binding Site BS01

Receptor Information
>4v9f Chain T (length=119) Species: 272569 (Haloarcula marismortui ATCC 43049) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKQPDKQRKSQRRAPLHERHKQVRATLSADLREEYGQRNVRVNAGDTVEV
LRGDFAGEEGEVINVDLDKAVIHVEDVTLEKTDGEEVPRPLDTSNVRVTD
LDLEDEKREARLESEDDSA
Ligand information
>4v9f Chain 0 (length=2808) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acuaugccagcugguggauugcucggcucaggcgcugaugaaggacgugc
caagcugcgauaagcuguggggagccgcacggaggcgaagaaccacagau
uuccgaaugagaaucucucuaacaauugcuucgcgcaaugaggaaccccg
agaacugaaacaucucaguaucgggaggaacagaaaacgcaacgugaugu
cguuaguaaccgcgagugaacgcgauacagcccaaaccgaagcccucacg
ggcaauguggugucagggcuaccucucaucagccgaccgucuucacgaag
ucucuuggaauagagcgugauacagggugacaaccccguacugaagacca
guacgcugugcgguagugccagaguagcggggguuggauaucccucgcga
auaacgcaggcaucgacugcgaaggcuaaacacaaccugagaccgauagu
gaacaaguagugugaacgaacgcugcaaaguacccucagaagggaggcga
aauagagcaugaaaucaguuggcgaucgagcgacagggcauacaaggucc
cuugacgaaugaccgagacgcgagucuccaguaagacucacgggaagccg
auguucugucguacguuuugaaaaacgagccagggagugugucuguaugg
caagucuaaccggaguauccggggaggcacagggaaaccgacauggccgc
agggcuuugcccgagggccgccgucuucaagggcggggagccauguggac
acgacccgaauccggacgaucuacgcauggacaagaugaagcgugccgaa
aggcacguggaagucuguuagaguugguguccuacaauacccucucguga
ucuauguguaggggugaaaggcccaucgaguccggcaacagcugguucca
aucgaaacaugucgaagcaugaccuccgccgagguagucugugagguaga
gcgaccgauugguguccuccugucaaacuccaaacuuacagacgcuguuu
gacgcggggauuccggugcgcgggguaagccuguguaccaggaggggaac
aacccagagauagguuaagguccccaaguguggauuaaguguaauccucu
gaagguggucucgagcccuagacagccgggaggugagcuuagaagcagcu
acccucuaagaaaagcguaacagcuuaccggccgagguuugaggcgccca
aaaugaucgggacucaaauccaccaccgagaccuguccguaccacucaua
cugguaaucgaguagauuggcgcucuaauuggauggaagcaggggcgaga
gcuccuguggaccgauuagugacgaaaauccuggccauaguagcagcgau
agucgggugagaaccccgacggccuaauggauaaggguuccucagcacug
cugaucagcugaggguuagccgguccuaagucucaccgcaacucgacuga
gacgaaaugggaaacagguuaauauuccugugccaucaugcagugaaagu
ugacgcccuggggucgaucacgccgggcauucgcccggucgaaccgucca
acuccguggaagccguaauggcaggaagcggacgaacggcggcauaggga
aacgugauucaaccuggggcccaugaaaagacgagcaugauguccguacc
gagaaccgacacagguguccauggcggcgaaagccaaggccugucgggag
caaccaacguuagggaauucggcaaguuagucccguaccuucggaagaag
ggaugccugcuccggaacggagcaggucgcagugacucggaagcucggac
ugucuaguaacaacauaggugaccgcaaauccgcaaggacucguacgguc
acugaauccugcccagugcagguaucugaacaccucguacaagaggacga
aggaccugucaacggcggggguuaugacccucuuaagguagcguaguacc
uugccgcaucaguagcggcuugcaugaauggauuaaccagagcuucacug
ucccaacguugggcccggugaacuguacauuccagugcggagucuggaga
cacccagggggaagcgaagacccuauggagcuuuacugcaggcugucgcu
gagacguggucgccgaucggugacugcgacucucacuccgggaggaggac
accgauagccgggcaguuugacuggggcgguacgcgcucgaaaagauauc
gagcgcgcccuauggucaucucagccgggacagagacccggcgaagagug
caagagcaaaagaugacuugacaguguucuucccaacgaggaacgcugac
gcgaaagcguggucuagcgaaccaauuagccugcuugaugcgggcaauug
augacagaaaagcuacccuagggauaacagagucgucacucgcaagagca
cauaucgaccgaguggcuugcuaccucgaugucgguucccuccauccugc
ccgugcagaagcgggcaagggugagguuguucgccuauuaaaggaggucg
ugagcuggguuuagaccgucgugagacaggucggcugcuaucuacugggu
guguaauggugucugacaagaacgaccguauaguacgagaggaacuacgg
uugguggccacugguguaccgguuguucgagagagcacgugccggguagc
cacgccacacgggguaagagcugaacgcaucuaagcucgaaacccacuug
gaaaagagacaccgccgaggucccgcguacaagacgcggucgauagacuc
ggggugugcgcgucgagguaacgagacguuaagcccacgagcacuaacag
accaaagc
....<<<<<<<<<<<.....((..((<<<<<<.[<<......<<<<<<.(
(..((.>>>.....<<<<<<...<<<))..)).>>>......>>>>>>..
.>>>....<<<...>>>.......<<<<<.....>>>>>.>>...<<<<<
<.....<......>......>>>>>.>.........<<.....>>...<<
<<<.....<<.....>>....>>>>>...<<<...<<<...<<<<....>
>>>.....>>>....<<<<<<<<......<<<<.....<<<<<<<.....
.<<<<......>>>>.((......<<<.....))>>>....>>>>>>>..
....>>>>...>>>>>>.>>......<<<<<<<........>>>>>>>..
....<<<<<.<<<<<<>>>>>..>>>......]..>>>>>>.))......
.........<<....>>....))..........<<<.....>>>......
.............>>>>>>>>>>>.......<<<<<<<<<<....<.<<<
<.<<<.........<<<<<....>>>>>.........>>>.>>>>...>.
>>>>>>>>>>...<<<........>>>.<<<<<<...<<<<<<<<<<<<<
<..<<<...<<<<<...>>>>>...>>>...<<....>>....<<<<<..
.<<<<...>>>>...>>>>><<<<<<....>>>>>>...>>>>>>>>>>>
>>>.<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<<...
.>>>>>>>.....>>>....<<<..<<.<<........>>>>.>>>....
>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<
<<<....<<<<<....>>>>><.<<<<<<...<<<.<<<<<<<<<...<<
<.....<<..<<......>>..>>...>>.>...>>>>>>>>>>>>....
...>>>>>>..>..<<<<<<.<<<.....>>>.>>>>>>....<<<....
..>>>...<<<<<<<...<<<(((.....<<<<<<.....<<........
...<<<.<<<<<<<<<<.......<<<<<.<<<..<<<<.......>>>>
..>>>.......<<<<......>>>>.>>>>>...>>>>>>>>>>>>>..
........)))>>....>>>>>>.>>>...>>>>>>><<<<<<<......
.>>>>>..>>....>>>>>><...<<<<<<<<......<<<<<<<<....
>>>>>>>>...>>>>>>>>....>.....>>>>>><<.....<.......
.<<<<<<.......>>>>>><<<<<...<<<<..<<...<<<<<<...<<
.....>>.>>>>>>....((<<<<<<...<<<<<<.<<.....>>..>>>
>>>.....>>>..<<<<<........>>>>>))<<<<<<<<.......<<
<...<<<<<<<<...<<<<<<<<<<<<<.(((>>>>>>><...<<<<<..
..<<<<<....<<<<...>>>>.....>>>>>.....>>>>>....>...
...>>>>>>...>>>>>>>>.........>>>..>>>>>>>>.>>>..>>
.....<<......>>.>>>>..<<<.......>>>.>>>>>...<<<<..
...<<<<<<<<.<<.........<.....<<<<<...............>
>>>><<<<<<<<<.....>>>>>>>>>............<<<<<<<<<..
<<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>
>>>.<<<<<.<<<..<<<<<<<..<<<.....<<<<......>>>>....
.>>>>>>>>..>>>>><<<<<<....>>>>>>........<.........
..<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..>.
.>>.>>>>>>>>.>>>>.>....>>.((.<<<<<<......))>>>>>>.
<<<<<<<..(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<..
<<<.<<<<<<<<<<<..>>>>>>>>>>>.>>>...<<<<....>>>>...
..>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<...........
>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.
..(((>>....>>>>>>>...<<<<<<<<<.........>>>>>>>>>.<
<<....>>>.>>))).......<<<<<.<<<<<.>>>>>>>>>>>>>>>>
..........>>>>..]]>>>>.......<<<<.<.<<<<<<...<<...
....>>...>>>>>>...>>>>.>.......<<<<<..<<<<<..<<<<<
<<<<......>>>>>>..>>>..<<<<.....>>>>......>>>>>...
...>>>.>>....<<<<<<<....>>>.>>>>....]]..))).>>>>>>
>.....<<<<<<<...<<<<..<<<<<<<<...............>>>>>
>>><<<<<...<<<<...<<<<<<<<<<))).>>>>>...>>>>>...>>
>>.>>>>>..<<<....<<<<<...........>>>>>....>>>.>>>>
.......>>>>>>>....<<<<<<<<<.......>>>>>....<<<.<<<
<<<<<....<<<<<..........>>>>>...>>>>.>>>>..>>>...>
>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v9f Revisiting the Haloarcula marismortui 50S ribosomal subunit model.
Resolution2.404 Å
Binding residue
(original residue number in PDB)
S1 K2 Q3 P4 D5 K6 Q7 R8 K9 Q11 R12 L16 H17 H20 K21 R24 T26 R32 R38 N39 R41 N43 A44 R52 G53 D54 V65 L67 L79 K81 T82 D83 V87 R89 P90 S94 N95 R97 D105 K107 R111
Binding residue
(residue number reindexed from 1)
S1 K2 Q3 P4 D5 K6 Q7 R8 K9 Q11 R12 L16 H17 H20 K21 R24 T26 R32 R38 N39 R41 N43 A44 R52 G53 D54 V65 L67 L79 K81 T82 D83 V87 R89 P90 S94 N95 R97 D105 K107 R111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v9f, PDBe:4v9f, PDBj:4v9f
PDBsum4v9f
PubMed23695244
UniProtP10972|RL24_HALMA Large ribosomal subunit protein uL24 (Gene Name=rpl24)

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