Structure of PDB 4tvx Chain T Binding Site BS01

Receptor Information
>4tvx Chain T (length=219) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD
TSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS
HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS
CPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEP
MITLPRQFASREWYVIKGG
Ligand information
>4tvx Chain X (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaaccgacgguauuguucagauccuggcuugccaacaggaguuccccg
cgcagcgggg
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Receptor-Ligand Complex Structure
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PDB4tvx Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		G17 Q18 P19 T20 R25 S34 G38 L39 G41 A42 I46 R48 H86 T87 V88 L89 R108 Y142 P144 Y145 G147 R148 R149 R197 R206 F208
Binding residue
(residue number reindexed from 1)		G17 Q18 P19 T20 R25 S34 G38 L39 G41 A42 I46 R48 H86 T87 V88 L89 R108 Y142 P144 Y145 G147 R148 R149 R197 R206 F208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tvx, PDBe:4tvx, PDBj:4tvx
PDBsum4tvx
PubMed25103409
UniProtQ46898|CAS5_ECOLI CRISPR system Cascade subunit CasD (Gene Name=casD)

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