Structure of PDB 3h1c Chain T Binding Site BS01

Receptor Information
>3h1c Chain T (length=543) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAK
PGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRP
LFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGA
ARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQM
LGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAE
ARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIE
KNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQAL
VTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREI
GHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALM
DAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDG
ISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAP
Ligand information
>3h1c Chain U (length=21) Species: 83333 (Escherichia coli K-12) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAAGGHTATHHASAAPARPQP
Receptor-Ligand Complex Structure
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PDB3h1c Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly
Resolution3.57 Å
Binding residue
(original residue number in PDB)		E320 D322 M323 I324 R325 G326 L327 V329 R330 T331 G332 V333 G528 A540
Binding residue
(residue number reindexed from 1)		E319 D321 M322 I323 R324 G325 L326 V328 R329 T330 G331 V332 G527 A539
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3h1c, PDBe:3h1c, PDBj:3h1c
PDBsum3h1c
PubMed19327365
UniProtP05055|PNP_ECOLI Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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