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Receptor Information

>3ela Chain T (length=191) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDT
ECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLE
TNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTL
YYWKTAKTNTNEFLIDVCFSVQAVIPSRTVNRKSTDSPVEC

Ligand ID

FUC

InChI

InChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6+/m0/s1

InChIKey

SHZGCJCMOBCMKK-SXUWKVJYSA-N

SMILES

Software	SMILES
CACTVS 3.341	C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
ACDLabs 10.04	OC1C(O)C(OC(O)C1O)C
OpenEye OEToolkits 1.5.0	CC1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.5.0	C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O)O)O)O
CACTVS 3.341	C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O

Formula

C6 H12 O5

Name

alpha-L-fucopyranose;
alpha-L-fucose;
6-deoxy-alpha-L-galactopyranose;
L-fucose;
fucose

PDB chain

3ela Chain L Residue 216 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3ela Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity
Resolution	2.2 Å
Binding residue (original residue number in PDB)	R131 F140
Binding residue (residue number reindexed from 1)	R126 F135
Annotation score	4

Enzyme Commision number

	Biological Process
GO:0007596	blood coagulation

	Cellular Component
GO:0016020	membrane

PDB	RCSB:3ela, PDBe:3ela, PDBj:3ela
PDBsum	3ela
PubMed	18640965
UniProt	P13726\|TF_HUMAN Tissue factor (Gene Name=F3)

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Structure of PDB 3ela Chain T Binding Site BS01