Structure of PDB 8bsj Chain Se Binding Site BS01

Receptor Information
>8bsj Chain Se (length=80) Species: 5741 (Giardia intestinalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNVDLLYPDPVEEQRKHKLKRLVQGPNSYFLEIKCAGCQDIVVVYSHANT
PVFCPGCTSQISIPTGGKCAFTSQVERYRQ
Ligand information
>8bsj Chain St (length=1454) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cauccggucgauccugccggagcgcgacgcucuccccaaggacgaagcca
ugcaugcccgcucacccgggacgcggcggacggcucaggacaacgguugc
accccccgcggcggucccugcuagccggacaccgcuggcaacccggcgcc
aagacgugcgcgcacgggcgcgcgccccgcgggcgagcagcgugacgcag
cgacggcccgcccgggcuuccggggcaucacccggucggcgcggucgcgg
cgcgccgagggcccgacgccuggcggagaaucaggguucgacuccggaga
gcgggccugcgagacggcccgcacauccaaggacggcagcaggcgcggaa
cuugcccaaugcgcggcgcgcgaggcagcgacggggagcgcgcgagcgag
gcgggcccacagcccccgccgcgcagccgagggcaaggucugugccagca
gccgcgguaauuccagcucggcgagcgucgcgcggcgcugcugcaguuga
aacgcccguaguuggccccccgccgccacgaggaaacgggagcgcuccag
gcaggcccguuggccccgccgcgugggaccgcgcagcgggcgcggcgcgc
cgccgccgcagccccgaggagagcgggcgggggcaccgguaccggccggg
gacgggugaaacaggaugaucccgccgagaccgccggccgcgcaggcgcc
ugccaagaccgccucugucaaucaagggcgaaggccgggggcuagaaggc
gaucagacaccaccguauucccggccguaaacggugccgccccgcggccg
gcgcgcgcgucccgccggccgcccagggaaaccgggaggcuccgggcucu
ggggggaguauggccgcaaggcugaaacuugaaggcauugacggaggggu
accaccagacguggagucugcggcucaaucugacucaacgcgcgcaccuc
accaggcccggacgcgcggaggaccgacagccgggcgcgcuuucgcgauc
gcgcgggugguggugcauggccgcucccagcccguggcgcgagccgucug
cuccauugcgacaacgagcgagaccccggccgcgggcgccgcgggacggc
ccgcggcagcgggaggacggcggggcgauagcaggucugugaugcccuca
gacgcccugggccgcacgcgcgcuacacuggcggggccagccggcgcccg
ccaggacgcgcggagcccccgccguggccgggaccgcgggcuggaacgcc
cccgcgcaccaggaaugucuuguaggcgcccgcccccaccgcgcgccgga
cgcgucccugccccuuguacacaccgcccgucgcuccuaccgacugggcg
cggcggcgagcgccccggacgcgcgaagggccgcgagcccccgcgccugg
aggaaggagaagucguaacaagguauccguaggugaaccugcggauggau
ccuu
...<<<<<.[..(((>>>>>.<<<<<<<<<..<<<<..........<<<.
<<<..<<<.<<...........>>>>>......<<........<<<..<<
..<<...<<<<..............<<.....<<<<<......>>>>>..
....>>........<.<.<<<<...[.[...<.....>..>>>>.>>...
.......>>>>..>>>>..>>>.<<<....<<<..<<<<<<<<.......
>>>>>>>>>>>......>>>...<<<<<<<<....>>>>...>>>>.>>.
<<<<<<..........>>>>>>.<.<<....>>.>...>>>>>>......
...<<<....<<<<...>>>>..>>>.......>>>>............<
<<<<<.........>>>>>>.....<<<<<<<......[........((.
.>>))..........].>>>>>..>>>>>>>>>..........<<<((..
...<<<<...<<<.......<<<.<<<<<<.......<<..<<.......
>>...........>>......>>>>>..>.>>>..<<<<<<.....].].
.>>>..>>>..........<<<<<<<.....<<<<..<<..<<<<<.<<<
..<.<......>.>.....>>>.>>>>.>.>>......<<<....>>>..
>>>>....>>>>.>>>...>>>...>>>>...<<<<<<<<...<...<<.
<.........>.>>...>>>>>>>>>.........<<<.<<..<<<<<<<
<<<.........>>>>>>>>>>...<<..))>>....>>.....>>>.>>
>.<<<......<<<<....>>>>....>>>..)))..]<<<<<.<<<<<<
<..<<.<<<<<<..<<<.<<<<........<<........>>........
.<<<<<.<....<<<<<<......<<<.<<<.......>>>.>>>....>
>>>>>...<<.<<<..<<.<<<<<<....<<.<<<<<<....>>>....<
........>....>>>.>>....<<<<..<<<<<<...>>>>>>.....<
<<<<....>>>>>........>>>>....>>>.>>>.....>>>>>>>..
...>.>>>>>......>>>>.>>>.....<<<<<<<.......<<<.<<.
...>>.>>>.......>>>>>>>...........<<.<<<<......>>>
>.>>..........>>>>>>....<<<<<.<<.......>>.>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<<<<
<<<.<<<..<<<.<<<...........>>>.>>>..>>>.>>>>>>>>..
.>>.>>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8bsj Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Resolution6.49 Å
Binding residue
(original residue number in PDB)		R58 H60 K61 L62 K63 N70 S71 Y72 F73 Y88 H90 N92 T108 G109 G110 K111
Binding residue
(residue number reindexed from 1)		R15 H17 K18 L19 K20 N27 S28 Y29 F30 Y45 H47 N49 T65 G66 G67 K68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:8bsj, PDBe:8bsj, PDBj:8bsj
PDBsum8bsj
PubMed36912103
UniProtA0A644F5K9

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