Structure of PDB 6ke6 Chain Sd Binding Site BS01

Receptor Information

>6ke6 Chain Sd (length=63) Species: 559292 (Saccharomyces cerevisiae S288C)

TPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDIL
VLMESEREARRLR

Ligand information

>6ke6 Chain SA (length=1310)

agauaguuaucugguugauccugccaguagucauaugcuugucucagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucauu
aaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauuc
uagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauua
gaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcauggc
cuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgaug
guaggauaguggccuaccaugguuucaacggguaacggggaauaaggguu
cgauuccggagagggagccugagaaacggcuaccacauccaaggaaggca
gcaggccaaauuacccaauccuaauucagggagguagugacaauaaauaa
cgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaau
accuuaacgaggaacaauuggagggcaagucuggugccagcagccgcggu
aauuccagcuccaauagcguauauuaaaguuguugcagaagcucguaguu
gaacuggcccgguuggccgguccggauuuccaacggggccuugauuaaua
gggacggucgggggcaucaguauucaauugucagaggugaaauucuugga
uuuauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauu
aaucaagaacgaccauaaacuaugccgacuagggaucgggugguguuuuu
uuaaugacccacucggcaccuuacgagaacuggggggaguauggucgcaa
ggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccu
gcggcucaacacggggaaacucaccagguccagacacaauaaggauugac
auucuugauuuugugggugguggugcauugaugcccuuguucugggccac
gcgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuu
gguaaucuugugaaacuccgucgugcuggggauauucaacgaggaauucc
uaguaagcgcaagucaucagcuugcguugauuacgucccugcccuuugua
cacaccgcccgucgcuaguaccgauugaauggcuuagugaggccucagga
ucugcuuagagaagggggcaacuccaucucagagcggagaauuuggacaa
acuuggucauuuagaggaacuaaaagucguaacaagguuuccguagguga
accugcggaa

...........................<<<<.<<<<<<...<....<<<.
<<...<<....<<....<<..........>>...>>.>>.....<<<...
....<<<..<<..<<....<<<..........<....<<<.<<<.....>
>>.>>.>....>.......<<<<............>>>>.....<<<<<.
..<<<<.<........>...>>>>...>>>>>.........<<<<..<<<
.....>>>.>>>>....>>>...>>>>..>>>.<.<....<<<....<<<
<<<<<.......>>>>>>>>>>>......>.>.....<<...........
....>>..>>>.<<.<<<..........>>>.>>...<<....>>.....
.>>>>>......<<<....<<<.....>>>..>>>.........>.....
<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<........
...>..>>.........<<<<<<.......<<<....>>>..........
........>>>>>>..>>>>>>>>>>..............<.<<...<<<
.<<..<<<<<.<<<<<..<.......>..>>>>>.>>>>>....>>....
<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>.....
.>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.>>>...
>>>...>>.>...............<<...<<<..<<<<<<<<.<<<...
.....>>>>>>>>>>>..>>>..>>.........................
..<<.........>>.....<<<<<<<<<<<<..<<.<<<<<<..<<<.<
<<<.......................<<......<<<<<...........
..........>>>>>......<<<........>>>.....>>.......>
>>>.>>>.....<<<<<<<............<<<..<<<<....>>>>..
>>>............>>>>>>>.......................>>>>>
>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>....
........>>>>>..<<<<.<<.....<<<<<<<.<<<..<.<<......
<<<<<<<...<<.<<<<....>>>>.>>...>>>>>>>......>>.>..
>>>.>>>>>>>....>>.>>>>................<<<<<<<<<...
.>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ke6 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
• Resolution: 3.4 Å
• Binding residue (original residue number in PDB): R18 G20 S21 G23 P47
• Binding residue (residue number reindexed from 1): R14 G16 S17 G19 P43

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0000054 ribosomal subunit export from nucleus
• GO:0006412 translation
• GO:0030490 maturation of SSU-rRNA
• GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ke6, PDBe:6ke6, PDBj:6ke6
• PDBsum: 6ke6
• UniProt: Q3E7X9|RS28A_YEAST Small ribosomal subunit protein eS28A (Gene Name=RPS28A)