Structure of PDB 5wyj Chain SZ Binding Site BS01

Receptor Information

>5wyj Chain SZ (length=101) Species: 559292 (Saccharomyces cerevisiae S288C)

SDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAE
KDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVE
K

Ligand information

>5wyj Chain SA (length=1115)

guugauccugcagucauaugcuugucucaaagccaugcaauggcucauua
aaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacugug
guaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagagau
guauuuauuagauucauaauaacuuuucgaaucgcauggccuugugcugg
cgaugguucauucaaauuucugcccuaucaacuuucgaugguaggauagu
ggccuaccaugguuucaacggguaacggggaauaaggguucgauuccgga
gagggagccugagaaacggcuaccacauccaaggaagggcaggcgcuuac
ccaauccuaauucagggagguagugacaauaaauaacgauacagggccca
uucgggucuuguaauuggaaugaguacaauguaaauaccuuaacgaggaa
caauuggagucuggucagcagccgcgcagcuccaauagcguauauuaagc
ucguaguugaacuuuaauagggacggucgggggcaucaguauucaauugu
cagaggugaaauucuuggauuuauugaagacuaacuacugcgaaagcauu
ugccaaggacguuuucauuaaucaagaacgaauagggaucgggugguguu
uuuuuaaugacccacucggcaccuuacgagaaaucggaguauggucgcaa
ugacggaagggcaccaccaggaguggagccugcggcacucaacacgaaac
ucaccagguccagacacaauaaggauugacagauugagagcucuuucuug
auuuugugggugguggugcauggccguacaggucugugaugcccuuagac
guucugggccacgcgcgcuacacugacggagccagcgagccuuggccgag
aggucuugguaaaaacuccgucgugcaacgaggaauuccuaguaagcgca
agucaucagcuugcguugauuacgucccugcccuuuguacacaccgcccg
ucgcuaguaccgauugaauggcuuagugaggccucaggaucugcgcggag
aauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaaguca
uuaaagaaauuuaau

...............<<<<<<..........<<<.<<<.....<<.....
...<<<..<<..<<....<<<..................<<....<<.<<
<.....>>>.>>.....>>.........<<<<<..<......>..>>>>>
..<.<<<<<<......>>>>>>.>.......<<<<..<<<.....>>>.>
>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<.....
..>>>>>>>>>>>......>>>...<<<.<<<......>>>....>>>.>
>.<<.<<<..........>>>.>>.<.<<....>>.>.>>>>>>...<<<
<....<<<.....>>>..>>>>..............<<.<<<...<<<<.
...>>>>...>>>..>>......<<..<...........>..>>......
...<<<<<<.<<<.............>>>>>>>>>..>>>>>>.....<.
<<...<<<.<<..>>....<<<<<<.<<...<<<<..<<<.<<<<<<.<.
..<<<......>>>......>.>>>>>>.>>>.......<<....>>...
>>>>...>>>>>.>>>...>>>...>>.>....<<<..<<<<<<<<.<<<
........>>>>>>>>>>>..>>>..........................
..<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<................
...<<<<<.<....<<<<<.<......<<.<<<........>>>.>>...
..>>>>>>...<<.<<<.....<<<<..>.>>>.......>>>>>.....
>.>>>>>....>>>>.>>>.....<<<<<<<........<<..<<<<...
.>>>>..>>......>>>>>>>............>>>>>>....<<<<<<
<<.......>>>>>>>>......>>...>>>>>>>>>>..........<<
.<..<<<<.<<....<<<<<<<<.<<<..<.<<.................
.....>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>.........<
<<<<<....>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5wyj Molecular architecture of the 90S small subunit pre-ribosome.
• Resolution: 8.7 Å
• Binding residue (original residue number in PDB): N34 K37 G59 R61 F64
• Binding residue (residue number reindexed from 1): N33 K36 G58 R60 F63

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5wyj, PDBe:5wyj, PDBj:5wyj
• PDBsum: 5wyj
• PubMed: 28244370
• UniProt: P0CX31|RS24A_YEAST Small ribosomal subunit protein eS24A (Gene Name=RPS24A)