Structure of PDB 7mqa Chain SY Binding Site BS01

Receptor Information
>7mqa Chain SY (length=237) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEY
LKALRKKALEKNPDEFYYKMTRVTPEQLKLMRTQDVKYIEMKRVAEAKKI
ERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVF
NRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIA
QKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRKR
Ligand information
>7mqa Chain L1 (length=1636) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accugguugauccugccaguagcauaugcuugucucaaagauuaagccau
gcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucauu
aaaucaguuaugguuccuuuggucgcucgcuccuuacuuggauaacugug
guaauucuagagcuaauacaugccgacgggcgcugacccccggggggaug
cgugcauuuaucagaucaaaaccaacccgccccucgggcgggcgccggcg
gcuuuggugacucuagauaaccucgggccgaucgcacgccccccguggcg
gcgacgacccauucgaacgucugcccuaucaacuuucgaugguagucgcc
gugccuaccauggugaccacgggugacggggaaucaggguucgauuccgg
agagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcg
caaauuacccacucccgacccggggagguagugacgaaaaauaacaauac
aggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauccuuu
aacgaggauccauuggagggcaagucuggugccagcagccgcgguagcuc
caauagcguauauuaaacugcaguuaaaaagcucguaguuggaucuuggg
agcgggcgggcgguccagccaccgcccguccccgccccuugccucucggc
gccggcccgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcc
ccgccuggauaccgcagcuaggaauaauggggaccgcgguucuaggaacu
gaggccaugauuaagagggacggccgggggcauucguauugcgccgcuag
aggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugc
caagaauguuuucauuaaucaagaacgaaagucggagguucgaagacgau
cagauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcggc
ggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuu
ggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugacg
gaagggcaccaccaggaguggagccugcggcacccggcccggacacggac
aggauugacagauugauagcucuuucucgauuccguggguuggugcaugg
ccguucguugguggagcgauuugguuaauuccgauaacgaacgagacucu
ggcaugcuagagggacaaguggcguucagccacccgagauugagcaauaa
caggucugugaugcccguccggggcacgcgcgcuacacugacuggcucag
cguguguacgccggcaggcgcgaaccccauucgugauggggaucggggau
uauuccccaugaacgaggaauucccaguaagugcgggucauaagcuugcg
uugauuaagucccugcccuuucacaccgcccgucgcuacuaccgauugga
ugguuuagugaggcccucggaucggccccgccggggucggcccacggccc
uggcggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaa
aguuccguaggugaaccugcggaaggaucauuaacg
..<<<<<.......>>>>>.<<.<<<<<<...<.<<.........<<<.<
<<..<<....<<....<<..........>>...>>.>>......<<....
....<<<.<....<<....<<<................<<.....<<.<<
.......>>.>>......>>.........<<<<...<<<<..>>>>...>
>>><<..<<<<<.....<<..<...<<..<<<<<..>>.>>>....>>.>
..>>...........>>>>>......>>...<<<<.<<<<......>>>>
>>>>....>>>...>>..>.>>>.<<<....<<<....<<<<<<<.....
....>>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.
>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>...
......<<<....<<<.....>>>..>>>......>>.>.....<<<<<<
<<<.<<<....>>>.>.>>>>.>>>>......<<..<...........>.
.>>.........<<<<<<.......<<<....>>>............>>>
>>>..>>>>>>.>>......<.<((.....<.<<...<<<.<<<<<.<<<
.<<<<<<<<<<<<<......>>>>>>>>>..>>>>>>>.<<<...<<<<.
<<..>>>>>>.>>>.<<<<<<.<.......<<..<<.......>>.<<<.
..>>>....>>......>.>>>..>>>.>><<.<<.<<<<<<<.>>>>>>
>.>>>>...>>>....<<<<<<..<...<<<<..<<..<<<<<<<<...<
<<......>>>......>>>>>>>>..>>.......<<....>>...>>>
>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<..
.......>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<
<<.<<<........>>>>>>>>>.>..>>>...<<..))>>...>>....
.>>>.>.>......................................<<<<
<<<<<<<<..<<..<<<<<..<<<.<<<<<<.<<<<<......<<<<<<.
......<<.<<<........>>>.>>.....>>>>>>....<<<.<<<<<
<<<<<.<<<.<<.<<....>>.<<......>>....>>.>>>....<<<.
..<...<..>..>.....<<<<<.....>>>>>........>>>....>>
>.>>.>>>>>..>>>...>>>>>>>.>>>>.>>>.....<<.<<<.....
........<<<<....>>>>......>>>.>>......<.....<<<<<.
<>.>>>>>.....>.....>>>>>.....<<<<<<<.........>>>>>
>>......>>...>>>>>>>.........>>>>>..<<<<.<<..<.<<<
<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<<<<<<.....>>>>>>
>>>>>>...>>>>>...>>.>>>>..>>>.>>>>>>>>.>.>>.>>>>..
..<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7mqa Nucleolar maturation of the human small subunit processome.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		M1 A3 A4 K7 K10 R12 Q13 R14 E15 H16 R17 R19 K33 Y37 K38 Y44 R45
Binding residue
(residue number reindexed from 1)		M1 A3 A4 K7 K10 R12 Q13 R14 E15 H16 R17 R19 K33 Y37 K38 Y44 R45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0007399 nervous system development
GO:0042274 ribosomal small subunit biogenesis
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0032040 small-subunit processome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtQ9Y3A2|UTP11_HUMAN Probable U3 small nucleolar RNA-associated protein 11 (Gene Name=UTP11)

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