Structure of PDB 7cpu Chain SY Binding Site BS01

Receptor Information
>7cpu Chain SY (length=110) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGG
KTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKV
RGTAKANVGA
Ligand information
>7cpu Chain S2 (length=1656) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucacuuggauaacugugguaauu
cuagagcuaauacaugccgacgggcgcauuuaucaguggugacucuagau
aaccgccgaucgcacgcccuggcggcgacgacccauucgaacgucugccc
uaucaacuuucgaugguagucgccgugccuaccauggugaccacggguga
cggggaaucaggguucgauuccggagagggagccugagaaacggcuacca
cauccaaggaaggcagcaggcgcgcaaauuacccacucccgacccgggga
gguagugacgaaaaauaacaauacaggacucuuucgaggcccuguaauug
gaaugaguccacuuuaaauccuuuaacgaggauccauuggagggcaaguc
uggugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguu
gcugcaguuaaaaagcucguaguuggaucuucucgaagcguuuacuuuga
aaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcagcua
ggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaacuga
ggccaugauuaagagggacggccgggggcauucguauugcgccgcuagag
gugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugcca
agaauguuuucauuaaucaagaacgaaagucggagguucgaagacgauca
gauaccgucguaguuccgaccauaaacgaugccgacuggcgaugcggcgg
cguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugg
guuccggggggaguaugguugcaaagcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacggga
aaccucacccggcccggacacggacaggauugacagauugauagcucuuu
cucgauuccgugggugguggugcauggccguucuuaguugguggagcgau
uugucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguu
acgcgacccccgagcggucggcguaacuucuuagagggacaaguggcguu
cagccacccgagauugagcaauaacaggucugugaugcccuuagaugucc
ggggcugcacgcgcgcuacacugacuggcucagcgugugccuacccugcg
ccggcaggcgcggguaacccguugaaccccauucgugauggggaucgggg
auugcaauuauuccccaugaacgaggaauucccaguaagugcgggucaua
agcuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuac
uaccgauuggaugguuuagugaggcccucggaucggccccgccggggucg
gcccacggcccuggcggagcgcugagaagacggucgaacuugacuaucua
gaggaaguaaaagucguaacaagguuuccguaggugaaccugcggaagga
ucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<..<
.....<<<......<<....<<<.........<<.....<<.<<......
.>>.>>......>>...........<<..<<<<<...<......>..>>>
>>..>>...<<<<.<<<<..>>>>>>>>....>>>...>>....>>>.<<
<....<<<....<<<<<<<.........>>>>>>>>>>......>>>...
<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.>>.
<.<<....>>.>...>>>>>>.........<<<....<<<<...>>>>..
>>>..>...>>.>.....<<.<<<<<<............>>.>>>.>.>>
......<<..<...........>..>>.........<<<<<((......<
<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>.>>>.....
....<.<((.....<.<<...<<<.<<...<.....>....<<<<<<.<.
......<<...<.......>..<<<.......>>>....>>......>.>
>>..>>>........<.<<.<<.........................>>.
>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>>..>>.......<<....>>...>>>>.
.>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<
.<<<<......>>>>>>>>>>.>..>>>...<<..))>>...>>.....>
>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<
<<<<<<..<<..<<<<<..<<<.<<<<........<<........>>...
.......<<<<<.<....<<<<<<.......<<.<<<........>>>.>
>.....>>>>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>
>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<
<<<<<<<<.......>>>>.>>>>>>>>..>>>>..>.....<<<<<...
..>>>>>........>>>....>>>.>>>...>.>>>>>>>.....>.>>
>>>......>>>>.>>>.....<<.<<<........<.......<<<<<<
<<....>>>>>>>>....>.........>>>.>>......<.....<<<<
<..........>>>>>.....>.....>>>>>.....<<<<<<<<.....
..>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<
<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.............
....................>>>>>...>>.>>>>..>>>.>>>>>>>>.
..>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>...
......
Receptor-Ligand Complex Structure
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PDB7cpu A male germ-cell-specific ribosome controls male fertility.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		A33 T34 V35 P36 K37 Y48 K49 G59 F60 R61 T62 H63 F64 G65 G66 H89 R93 R104 K105 K108 E109 K111 N112 K115 K116 G119 N124
Binding residue
(residue number reindexed from 1)		A16 T17 V18 P19 K20 Y31 K32 G42 F43 R44 T45 H46 F47 G48 G49 H72 R76 R87 K88 K91 E92 K94 N95 K98 K99 G102 N107
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
GO:0140236 translation at presynapse
GO:0140242 translation at postsynapse
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0044391 ribosomal subunit
GO:0045202 synapse
GO:0098793 presynapse
GO:0098794 postsynapse
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7cpu, PDBe:7cpu, PDBj:7cpu
PDBsum7cpu
PubMed36517592
UniProtP62849|RS24_MOUSE Small ribosomal subunit protein eS24 (Gene Name=Rps24)

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