Structure of PDB 6lqp Chain SY Binding Site BS01

Receptor Information
>6lqp Chain SY (length=103) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDG
CLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKE
KPR
Ligand information
>6lqp Chain SA (length=1325) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcagaagcucguagu
ugaacuggcccgguuggccgguccggauuuccaacggggccuugguucuc
uaggacugauuaauagggacggucgggggcaucaguauucaauugucaga
ggugaaauucuuggauuuauugaagacuaacuacugcgaaagcauuugcc
aaggacguuuucauuaaucaagaacgaccauaaacuaugccgacuaggga
ucgggugguguuuuuuuaaugacccacucggcaccuuacgagaacugggg
ggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacca
ccaggaguggagccugcggcucaacacggggaaacucaccagguccagac
acaauaaggauugacauucuugauuuugugggugguggugcauugaugcc
cuuguucugggccacgcgcgcuacacugacggagccagcgagucuaaccu
uggccgagaggucuugguaaucuugugaaacuccgucgugcuggggauau
ucaacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuu
agugaggccucaggaucugcuuagagaagggggcaacuccaucucagagc
ggagaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaa
gguuuccguaggugaaccugcggaa
............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<....<.<<...<<
<.<<..<<<<<.<<<<<..<.......>..>>>>>.>>>>>....<....
.>.......>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<
<......>>>......>.>>>>>>..>>.......<<....>>...>>>>
...>>>>>.>>>...>>>...>>.>...............<<...<<<..
<<<<<<<<.<<<........>>>>>>>>>>>..>>>..>>......>...
.................<<.........>>.....<<<<<<<<<<<<..<
<.<<<<<<..<<<.<<<<.......................<<.<....<
<<<<........<.....>......>>>>>......<<<........>>>
...>.>>.......>>>>.>>>.....<<<<<<<............<<<.
.<<<<....>>>>..>>>............>>>>>>>.............
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>..<<<<.<<.....<<<<<<<.
<<<..<.<<......<<<<<<<...<<.<<<......>>>.>>...>>>>
>>>......>>.>..>>>.>>>>>>>....>>.>>>>.............
...<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqp Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		S47 K62 Q63 P64 N65 A105 G106 K110 K123 K126 S131 K139
Binding residue
(residue number reindexed from 1)		S6 K21 Q22 P23 N24 A64 G65 K69 K82 K85 S90 K98
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
GO:0006450 regulation of translational fidelity
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqp, PDBe:6lqp, PDBj:6lqp
PDBsum6lqp
PubMed32943522
UniProtP0CX29|RS23A_YEAST Small ribosomal subunit protein uS12A (Gene Name=RPS23A)

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