Structure of PDB 8a3w Chain SW Binding Site BS01

Receptor Information
>8a3w Chain SW (length=111) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFTYRGLEIDPLLALSEEEFKALVHARARRNMNRHADRRPPVLLKRLREA
KKHVKPKAVKTHLRDVVITPEMVGSVVAIYNGHQFNAVEIKGEMIGHYLG
EFSMSYRPVLH
Ligand information
>8a3w Chain S1 (length=1663) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaau
cagacguaaucugccgcaaaaaucuugcggcaaaauuggauaacuuggcg
aaacgccaagcuaauacaugaaccaaccgggugucuccgagacgcccagc
gaaugaaugacaaaaccaaugccgcaguaacacccagcaguguugacuca
auucauuccgugcgaaagccggcuuccggcgucuuuugacgaacaacugc
ccuaucagcuggugauggccguguaguggacugccauggcguugacggga
gcgggggauuaggguucgauuccggagagggagccugagaaauagcuacc
acuucuacggagggcagcaggcgcgcaaauugcccaaugucaaaacaaaa
cgaugaggcagcgaaaagaaauagaguuauuucaaugggggauauuuaaa
cccaucccgagacaauuggaggacaagucuggugccagcacccgcgguaa
uuccagcuccaaaagcguauauuaaugcuguugcuguuaaaggguucgua
guugaacugugggcugcagcccgugaaagaaaaacacgggaggggugcau
gucaugcaugccguccgugauuuuuuacugugacuaaagaagcgugacua
aagcagucaugacuugaauuagaaagcaugggauaacaaaggagcuuuuu
aaagguuggagauuauggagcugugcgacaaaugggaaugaaggagggua
guucgggggagaacguacuggggcgucagaggugaaauucuuagaccgca
ccaagacgaacuacagcgaaggcauucuucaaggauaccuuccucaauca
agaaccaaaguguggagaucgaagaugauuagaaaccauuguaguccaca
cugcaaacgaugacacccaugaauuggggauaucuucacguuuucuguuu
uacgcgaaagcuuugagguuacagucucaggggggaguacguucgcaaga
gugaaacuuaaagaaauugacggaauggcaccacaagacguggagcgugc
gguuuaauuugacucaacacggggaacuuuaccagauccggacagggauu
gacagauugaguguucuuucucgauucccugaaugguggugcauggccgc
uuauggucgguggagugauuuguuugguugauuccgucaacggacgagau
ccaagcugcccaguagaauucagaauuauucggaauucuucucugcggga
uuccuuuguagcacaaggugaaauuuugggcaacagcaggucugugaugc
uccucaauguucugggcgacacgcgcacuacaaugucagugagaacaaga
acuacuugaucaaaagaguggggaaaccccggaaucacauagacccacuu
gggaccgaggauugcaauuauuggucgcgcaacgaggaaugucucguagg
cgcagcucaucaaacugugccgauuacgucccugccauuuguacacaccg
cccgucguuguuuccgaugauggugcaauacaggugaucggacgaaaguu
caccgauauuucuucaauagaggaagcaagucguaacaagguagcuguag
gaccugcagcugg
...<<<<<.{.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<..<....
<<<..<<..<<...<<.<<.....<<<<.>>>>...<<.....<<<<<<.
....>>>>>>......>>..........<<<<<<<<<.>>>>>>>>>.<<
<<<<<<<<.....((.{..{<<.>>.........................
>>>>>>>>...>>....<<<<<...>>>>>...>>.>>..>>>>..>>>.
<<<....<<<....<<<<<.<<.......>>.>>>>>>>>......>>>.
.<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.>>
.<<<<....>>>>...>>>>>>.........<<<....<<<.........
.>>>..>>>..>....>>>....<<<....>>>.....<<<<........
....>>>>.......<<<<<((....<.<<<<.....<<..))>>.....
..>>>>>>>>>>..>>>>>>>>>>.........<<<[[.....<<<<...
<<<..<....<........>...........<..............<<<<
.......>>>>.........>...<<<<<<<<.......<<...<.....
..>..<<<..>>>.....>>......>>>>>..>>>..........<<.<
<.<<...}..}.))......>>.>>.>>..........>......<<<<<
..<<...<<<<<<<<..<<<<.<<<...<<<......>>>......>>>.
>>>.>.>>.......<<....>>.>>>>>>...>>>>>.>>....>>>..
.>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>
>>.........<<<.<<...<<<<.<<<<<<.<....>.>>>>>>.>>>>
...<<..]]>>.....>>.....>>>.>>>.<<<......<<<<....>>
>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<.<<<<
<<<......<<........>>..........<<<<<.<....<<<<....
<<.<<<........>>>.>>.......>>>>...<<.<<<..<<.<<<<<
<....<<<.<<<<......>>...<<<......>>>...>>.>>>....<
<<<<.<<<<.....<<<<<<<.<<<<.>>>>.>>>>>>>.....>>>>..
..<<<<........>>>>.......>>>>>....>>>.>>>.....>>>>
>>>.....>.>>>>>...>>.>>>>>.>>.....<<<.<<<.......<.
..<.<.<..........>.>.>....>........>>>...>>>......
<....<<<..<..........>..>>>.....>.....>>>>>>....<<
<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>.....
..<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.<........>.>
>>>>..>>>>.>.>>>.>>..>>>>>>>>>.>>.........<<<<<<<<
<.>>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)		R25 H45 A46 R47 R49 R50 R54 R59 P60 H86 R88 D89 Y104 G106 H107 Y122 E125 S129 Y130 V133 H135
Binding residue
(residue number reindexed from 1)		R5 H25 A26 R27 R29 R30 R34 R39 P40 H62 R64 D65 Y80 G82 H83 Y98 E101 S105 Y106 V109 H111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4QBV0

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