Structure of PDB 8fkx Chain SU Binding Site BS01

Receptor Information
>8fkx Chain SU (length=552) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IEEHLIERKKKLQEKKMHIAALASAILSDPENNIKKLKELRSMLMEQDPD
VAVTVRKLVIVSLMELFKDITPSYKIRKETQKLREFEEGLVSQYKFYLEN
LEQMVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNN
IIVLIVPLMNDMSKLISEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKG
RNYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKLERELREAEASESTEK
KLKLHTETLNIVFVTYFRILKKAQRSPLLPAVLEGLAKFAHLINVEFFDD
LLVVLHTLIESGDLSYQESLHCVQTAFHILSGQGDVLNIDPLKFYTHLYK
TLFKLHAGATNEGVEIVLQCLDVMLTKRRKQVSQQRALAFIKRLCTLALH
VLPNSSIGILATTRILMHTFPKTDLLLDSESQGSGVFLPELDEPEYCNAQ
NTALWELHALRRHYHPIVQRFAAHLIAGAPSEGSGALKPELSRRSATELF
EAYSMAEMTFNPPVESSNPKIKGKFLQGDSFLNEDLNQLIKRYSSEVATE
SP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8fkx Chain SU Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8fkx Principles of human pre-60 S biogenesis.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		L661 D664
Binding residue
(residue number reindexed from 1)		L425 D428
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0003723 RNA binding
Biological Process
GO:0006270 DNA replication initiation
GO:0045444 fat cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0016607 nuclear speck

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fkx, PDBe:8fkx, PDBj:8fkx
PDBsum8fkx
PubMed37410842
UniProtQ8WTT2|NOC3L_HUMAN Nucleolar complex protein 3 homolog (Gene Name=NOC3L)

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