Structure of PDB 8a3w Chain SU Binding Site BS01

Receptor Information

>8a3w Chain SU (length=154) Species: 347515 (Leishmania major strain Friedlin)

YYHAHAVDATIQHEKAYQRQTAVNENMHRPSRKHVNKSGHIRYSKKIGLG
FKTPAKALNGKYIDRKCPFTSNVVIRGRILRGVVHSTKMHRTIIIRRNYL
HFIKKYQRYQKRHKSLAVHCSPAFDPKQGDEVVIGQCRPLSKTIRYNVLE
VVSK

Ligand information

>8a3w Chain S1 (length=1663)

gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaau
cagacguaaucugccgcaaaaaucuugcggcaaaauuggauaacuuggcg
aaacgccaagcuaauacaugaaccaaccgggugucuccgagacgcccagc
gaaugaaugacaaaaccaaugccgcaguaacacccagcaguguugacuca
auucauuccgugcgaaagccggcuuccggcgucuuuugacgaacaacugc
ccuaucagcuggugauggccguguaguggacugccauggcguugacggga
gcgggggauuaggguucgauuccggagagggagccugagaaauagcuacc
acuucuacggagggcagcaggcgcgcaaauugcccaaugucaaaacaaaa
cgaugaggcagcgaaaagaaauagaguuauuucaaugggggauauuuaaa
cccaucccgagacaauuggaggacaagucuggugccagcacccgcgguaa
uuccagcuccaaaagcguauauuaaugcuguugcuguuaaaggguucgua
guugaacugugggcugcagcccgugaaagaaaaacacgggaggggugcau
gucaugcaugccguccgugauuuuuuacugugacuaaagaagcgugacua
aagcagucaugacuugaauuagaaagcaugggauaacaaaggagcuuuuu
aaagguuggagauuauggagcugugcgacaaaugggaaugaaggagggua
guucgggggagaacguacuggggcgucagaggugaaauucuuagaccgca
ccaagacgaacuacagcgaaggcauucuucaaggauaccuuccucaauca
agaaccaaaguguggagaucgaagaugauuagaaaccauuguaguccaca
cugcaaacgaugacacccaugaauuggggauaucuucacguuuucuguuu
uacgcgaaagcuuugagguuacagucucaggggggaguacguucgcaaga
gugaaacuuaaagaaauugacggaauggcaccacaagacguggagcgugc
gguuuaauuugacucaacacggggaacuuuaccagauccggacagggauu
gacagauugaguguucuuucucgauucccugaaugguggugcauggccgc
uuauggucgguggagugauuuguuugguugauuccgucaacggacgagau
ccaagcugcccaguagaauucagaauuauucggaauucuucucugcggga
uuccuuuguagcacaaggugaaauuuugggcaacagcaggucugugaugc
uccucaauguucugggcgacacgcgcacuacaaugucagugagaacaaga
acuacuugaucaaaagaguggggaaaccccggaaucacauagacccacuu
gggaccgaggauugcaauuauuggucgcgcaacgaggaaugucucguagg
cgcagcucaucaaacugugccgauuacgucccugccauuuguacacaccg
cccgucguuguuuccgaugauggugcaauacaggugaucggacgaaaguu
caccgauauuucuucaauagaggaagcaagucguaacaagguagcuguag
gaccugcagcugg

...<<<<<.{.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<..<....
<<<..<<..<<...<<.<<.....<<<<.>>>>...<<.....<<<<<<.
....>>>>>>......>>..........<<<<<<<<<.>>>>>>>>>.<<
<<<<<<<<.....((.{..{<<.>>.........................
>>>>>>>>...>>....<<<<<...>>>>>...>>.>>..>>>>..>>>.
<<<....<<<....<<<<<.<<.......>>.>>>>>>>>......>>>.
.<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.>>
.<<<<....>>>>...>>>>>>.........<<<....<<<.........
.>>>..>>>..>....>>>....<<<....>>>.....<<<<........
....>>>>.......<<<<<((....<.<<<<.....<<..))>>.....
..>>>>>>>>>>..>>>>>>>>>>.........<<<[[.....<<<<...
<<<..<....<........>...........<..............<<<<
.......>>>>.........>...<<<<<<<<.......<<...<.....
..>..<<<..>>>.....>>......>>>>>..>>>..........<<.<
<.<<...}..}.))......>>.>>.>>..........>......<<<<<
..<<...<<<<<<<<..<<<<.<<<...<<<......>>>......>>>.
>>>.>.>>.......<<....>>.>>>>>>...>>>>>.>>....>>>..
.>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>
>>.........<<<.<<...<<<<.<<<<<<.<....>.>>>>>>.>>>>
...<<..]]>>.....>>.....>>>.>>>.<<<......<<<<....>>
>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<.<<<<
<<<......<<........>>..........<<<<<.<....<<<<....
<<.<<<........>>>.>>.......>>>>...<<.<<<..<<.<<<<<
<....<<<.<<<<......>>...<<<......>>>...>>.>>>....<
<<<<.<<<<.....<<<<<<<.<<<<.>>>>.>>>>>>>.....>>>>..
..<<<<........>>>>.......>>>>>....>>>.>>>.....>>>>
>>>.....>.>>>>>...>>.>>>>>.>>.....<<<.<<<.......<.
..<.<.<..........>.>.>....>........>>>...>>>......
<....<<<..<..........>..>>>.....>.....>>>>>>....<<
<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>.....
..<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.<........>.>
>>>>..>>>>.>.>>>.>>..>>>>>>>>>.>>.........<<<<<<<<
<.>>>>>>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
• Resolution: 2.89 Å
• Binding residue (original residue number in PDB): E20 A28 N30 M33 K39 Y49 K52 G54 L55 R71 K72 S77 I81 R82 R84 M95 Y105 K111 K117 R118 H119 K120 R144 P145 S147 K148 T149 R151 Y152
• Binding residue (residue number reindexed from 1): E14 A22 N24 M27 K33 Y43 K46 G48 L49 R65 K66 S71 I75 R76 R78 M89 Y99 K105 K111 R112 H113 K114 R138 P139 S141 K142 T143 R145 Y146

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 16 01:50:10 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '8a3w', asym_id = 'SU', bs = 'BS01', title = 'CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='8a3w', asym_id='SU', bs='BS01', title='CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412', uniprot = '', pdbid = '8a3w', asym_id = 'SU'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412', uniprot='', pdbid='8a3w', asym_id='SU')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>