Structure of PDB 7ug7 Chain SS Binding Site BS01

Receptor Information
>7ug7 Chain SS (length=84) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAV
HNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAA
Ligand information
>7ug7 Chain 16 (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacagguuugcugacgaguggcggacgggu
gaguaaugucugggaaacugccugauggagggggauaacuacuggaaacg
guagcuaauaccgcauaacgucgcaagaccaaagagggggaccuucgggc
cucuugccaucggaugugcccagaugggauuagcuaguaggugggguaac
ggcucaccuaggcgacgaucccuagcuggucugagaggaugaccagccac
acuggaacugagacacgguccagacuccuacgggaggcagcaguggggaa
uauugcacaaugggcgcaagccugaugcagccaugccgcguguaugaaga
aggccuucggguuguaaaguacuuucagcggggaggaagggaguaaaguu
aauaccuuugcucauugacguuacccgcagaagaagcaccggcuaacucc
gugccagcagccgcgguaauacggagggugcaagcguuaaucggaauuac
ugggcguaaagcgcacgcaggcgguuuguuaagucagaugugaaaucccc
gggcucaaccugggaacugcaucugauacuggcaagcuugagucucguag
agggggguagaauuccagguguagcggugaaaugcguagagaucuggagg
aauaccgguggcgaaggcggcccccuggacgaagacugacgcucaggugc
gaaagcguggggagcaaacaggauuagauacccugguaguccacgccgua
aacgaugucgacuuggagguugugccggcguggcuuccggagcuaacgcg
uuaagucgaccgccuggggaguacggccgcaagguuaaaacucaaaugaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaugcaa
cgcgaagaaccuuaccuggucuugacauccacggaaguuuucagagauga
gaaugugccuucgggaaccgugagacaggugcugcauggcugucgucagc
ucguguugugaaauguuggguuaagucccgcaacgagcgcaacccuuauc
cuuuguugccagcgguccggccgggaacucaaaggagacugccagugaua
aacuggaggaagguggggaugacgucaagucaucauggcccuuacgacca
gggcuacacacgugcuacaauggcgcauacaaagagaagcgaccucgcga
gagcaagcggaccucauaaagugcgucguaguccggauuggagucugcaa
cucgacuccaugaagucggaaucgcuaguaaucguggaucagaaugccac
ggugaauacguucccgggccuuguacacaccgcccgucacaccaugggag
uggguugcaaaagaaguagguagcuuaaccuucgggagggcgcuuaccac
uuugugauucaugacuggggugaagucguaacaagguaaccguaggggaa
ccugcgguuggauc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<..<<<.....>>>>>..>>>>>......<<
.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<......>
>>>>......>>.>.....<<<....>>>....<<<<<<..<<....>>>
>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<......
...>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>
.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>.....
....<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<<.....
.<<<<....>>>>.....>>>>...<.<<<<<......<.<<<<<<<<..
.....>>>>>>>>.>........>>>>>....>..<<<<<(((...<<<<
<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>........
..<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<
<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<..
.<<<<<<<....<<<<<<<<...<<<......>>>......>>>>>>>>.
..........<<....>>.>>>>>>>..>>>>.>>>>...>>>...>>>>
....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>....
......<<<<<<.<<<<<<<<<<<<..>>>>>>>>>>>>..<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<.<<<<<..<<<<<<<....>>>
>>>>...<<....>>..>>>>>.>...<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<...<<..<<<.....>>>>>....>>>>>>>.....<<<<<....
.>>>>>........>>>>.........>>>...>>>>>>>>....>>>>>
>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<...<<<....
>>>...>>....>>>.....>>>>>>>......<....<<<<<<<.....
...>>>>>>>....>.....>>>>>>....<<<<<<<.........>>>>
>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<
<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>>>>>>>>>>...
>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....
>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ug7 The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Resolution2.58 Å
Binding residue
(original residue number in PDB)		P2 R3 S4 L5 K6 K7 F10 H14 K17 K18 K21 W34 R36 R37 H52 G54 R55 K70 G72 E73 T77 R78 T79 Y80 R81 H83
Binding residue
(residue number reindexed from 1)		P1 R2 S3 L4 K5 K6 F9 H13 K16 K17 K20 W33 R35 R36 H51 G53 R54 K69 G71 E72 T76 R77 T78 Y79 R80 H82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ug7, PDBe:7ug7, PDBj:7ug7
PDBsum7ug7
PubMed35500116
UniProtP0A7U3|RS19_ECOLI Small ribosomal subunit protein uS19 (Gene Name=rpsS)

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